STRINGSTRING
A0A1L9X505 A0A1L9X505 A0A1L9X3Y9 A0A1L9X3Y9 A0A1L9X3W7 A0A1L9X3W7 A0A1L9X3V8 A0A1L9X3V8 A0A1L9X199 A0A1L9X199 A0A1L9WZN4 A0A1L9WZN4 A0A1L9WY17 A0A1L9WY17 A0A1L9WXU0 A0A1L9WXU0 A0A1L9WXT4 A0A1L9WXT4 KAE1 KAE1 A0A1L9WM34 A0A1L9WM34 A0A1L9WLS2 A0A1L9WLS2 A0A1L9WL08 A0A1L9WL08 A0A1L9WKV2 A0A1L9WKV2 A0A1L9WK55 A0A1L9WK55 A0A1L9WI19 A0A1L9WI19 A0A1L9WH52 A0A1L9WH52 A0A1L9WGG1 A0A1L9WGG1 A0A1L9WEP1 A0A1L9WEP1 A0A1L9X9L3 A0A1L9X9L3 A0A1L9X8D3 A0A1L9X8D3 A0A1L9X659 A0A1L9X659 A0A1L9XA15 A0A1L9XA15 A0A1L9WXC1 A0A1L9WXC1 A0A1L9WUP2 A0A1L9WUP2 A0A1L9WTW5 A0A1L9WTW5 A0A1L9WRX3 A0A1L9WRX3 A0A1L9WRM1 A0A1L9WRM1 A0A1L9WNY0 A0A1L9WNY0 A0A1L9WNM3 A0A1L9WNM3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A1L9X505Threonylcarbamoyl-AMP synthase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (434 aa)
A0A1L9X3Y9DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (623 aa)
A0A1L9X3W7ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. (723 aa)
A0A1L9X3V8Uncharacterized protein. (367 aa)
A0A1L9X199Uncharacterized protein. (1541 aa)
A0A1L9WZN4Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2897 aa)
A0A1L9WY17Stn1 domain-containing protein. (303 aa)
A0A1L9WXU0Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (324 aa)
A0A1L9WXT4DRMBL domain-containing protein. (483 aa)
KAE1tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] (359 aa)
A0A1L9WM34Checkpoint protein; Belongs to the HUS1 family. (381 aa)
A0A1L9WLS2Telo_bind domain-containing protein. (621 aa)
A0A1L9WL08Uncharacterized protein. (370 aa)
A0A1L9WKV2Uncharacterized protein. (1702 aa)
A0A1L9WK55Telomere_reg-2 domain-containing protein. (1001 aa)
A0A1L9WI19Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2462 aa)
A0A1L9WH52HD domain-containing protein. (240 aa)
A0A1L9WGG1SAP domain-containing protein. (654 aa)
A0A1L9WEP1Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (605 aa)
A0A1L9X9L3CUE domain-containing protein. (907 aa)
A0A1L9X8D3Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (821 aa)
A0A1L9X659Rif1_N domain-containing protein. (1800 aa)
A0A1L9XA15HABP4_PAI-RBP1 domain-containing protein. (304 aa)
A0A1L9WXC1J domain-containing protein. (324 aa)
A0A1L9WUP2Uncharacterized protein. (1066 aa)
A0A1L9WTW5EthD domain-containing protein. (162 aa)
A0A1L9WRX3HTH myb-type domain-containing protein. (881 aa)
A0A1L9WRM1HTH APSES-type domain-containing protein. (463 aa)
A0A1L9WNY0AAA_23 domain-containing protein. (1301 aa)
A0A1L9WNM3Sm domain-containing protein. (2388 aa)
Your Current Organism:
Aspergillus aculeatus
NCBI taxonomy Id: 690307
Other names: A. aculeatus ATCC 16872, Aspergillus aculeatus ATCC 16872
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