node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A0A1L9WLZ9 | A0A1L9WT07 | A0A1L9WLZ9 | A0A1L9WT07 | zf-C2HE domain-containing protein. | Uncharacterized protein. | 0.525 |
A0A1L9WLZ9 | FEN1 | A0A1L9WLZ9 | A0A1L9WXQ0 | zf-C2HE domain-containing protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.523 |
A0A1L9WNM3 | A0A1L9WT07 | A0A1L9WNM3 | A0A1L9WT07 | Sm domain-containing protein. | Uncharacterized protein. | 0.642 |
A0A1L9WNM3 | A0A1L9WUE0 | A0A1L9WNM3 | A0A1L9WUE0 | Sm domain-containing protein. | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | 0.804 |
A0A1L9WNM3 | A0A1L9X8F6 | A0A1L9WNM3 | A0A1L9X8F6 | Sm domain-containing protein. | Uncharacterized protein. | 0.450 |
A0A1L9WNM3 | FEN1 | A0A1L9WNM3 | A0A1L9WXQ0 | Sm domain-containing protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.509 |
A0A1L9WT07 | A0A1L9WLZ9 | A0A1L9WT07 | A0A1L9WLZ9 | Uncharacterized protein. | zf-C2HE domain-containing protein. | 0.525 |
A0A1L9WT07 | A0A1L9WNM3 | A0A1L9WT07 | A0A1L9WNM3 | Uncharacterized protein. | Sm domain-containing protein. | 0.642 |
A0A1L9WT07 | A0A1L9WXT4 | A0A1L9WT07 | A0A1L9WXT4 | Uncharacterized protein. | DRMBL domain-containing protein. | 0.588 |
A0A1L9WT07 | FEN1 | A0A1L9WT07 | A0A1L9WXQ0 | Uncharacterized protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.902 |
A0A1L9WUE0 | A0A1L9WNM3 | A0A1L9WUE0 | A0A1L9WNM3 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | Sm domain-containing protein. | 0.804 |
A0A1L9WUE0 | A0A1L9WXT4 | A0A1L9WUE0 | A0A1L9WXT4 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | DRMBL domain-containing protein. | 0.663 |
A0A1L9WUE0 | A0A1L9X8F6 | A0A1L9WUE0 | A0A1L9X8F6 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | Uncharacterized protein. | 0.500 |
A0A1L9WXT4 | A0A1L9WT07 | A0A1L9WXT4 | A0A1L9WT07 | DRMBL domain-containing protein. | Uncharacterized protein. | 0.588 |
A0A1L9WXT4 | A0A1L9WUE0 | A0A1L9WXT4 | A0A1L9WUE0 | DRMBL domain-containing protein. | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | 0.663 |
A0A1L9WXT4 | FEN1 | A0A1L9WXT4 | A0A1L9WXQ0 | DRMBL domain-containing protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.482 |
A0A1L9X8F6 | A0A1L9WNM3 | A0A1L9X8F6 | A0A1L9WNM3 | Uncharacterized protein. | Sm domain-containing protein. | 0.450 |
A0A1L9X8F6 | A0A1L9WUE0 | A0A1L9X8F6 | A0A1L9WUE0 | Uncharacterized protein. | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | 0.500 |
FEN1 | A0A1L9WLZ9 | A0A1L9WXQ0 | A0A1L9WLZ9 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | zf-C2HE domain-containing protein. | 0.523 |
FEN1 | A0A1L9WNM3 | A0A1L9WXQ0 | A0A1L9WNM3 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Sm domain-containing protein. | 0.509 |