(33 nodes) Preribosome, large subunit precursor network (Aspergillus aculeatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L9WH75	Uncharacterized protein. (290 aa)
	TIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (247 aa)
	A0A1L9WLJ6	Uncharacterized protein. (246 aa)
	A0A1L9WM65	Protein MAK16; Belongs to the MAK16 family. (333 aa)
	A0A1L9WMT7	Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (692 aa)
	A0A1L9WMX9	60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (185 aa)
	A0A1L9X905	Uncharacterized protein. (368 aa)
	A0A1L9WPG5	C2H2-type domain-containing protein. (112 aa)
	SPB1	AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (812 aa)
	A0A1L9WSC9	Uncharacterized protein. (377 aa)
	A0A1L9WTX8	Uncharacterized protein. (261 aa)
	A0A1L9WV35	Uncharacterized protein. (344 aa)
	A0A1L9WVR5	Uncharacterized protein. (340 aa)
	A0A1L9WW37	PUM-HD domain-containing protein. (710 aa)
	A0A1L9WWS6	CP-type G domain-containing protein. (542 aa)
	A0A1L9XA64	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (218 aa)
	A0A1L9X967	RNA helicase. (647 aa)
	A0A1L9WY59	Uncharacterized protein. (364 aa)
	A0A1L9WYF9	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (655 aa)
	A0A1L9WYM7	Brix domain-containing protein. (358 aa)
	A0A1L9WZI5	Uncharacterized protein. (409 aa)
	A0A1L9X0M0	Uncharacterized protein. (389 aa)
	A0A1L9X370	Brix domain-containing protein. (459 aa)
	A0A1L9X387	Uncharacterized protein. (745 aa)
	ERB1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (782 aa)
	YTM1	Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (486 aa)
	NOP7	Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (673 aa)
	A0A1L9X6J4	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (561 aa)
	A0A1L9X704	Uncharacterized protein. (248 aa)
	A0A1L9X804	Uncharacterized protein. (818 aa)
	A0A1L9X893	Uncharacterized protein. (799 aa)
	A0A1L9WEP4	Uncharacterized protein; Belongs to the DEAD box helicase family. (498 aa)
	A0A1L9WKQ9	Brix domain-containing protein. (443 aa)

Your Current Organism:

Aspergillus aculeatus

NCBI taxonomy Id: 690307
Other names: A. aculeatus ATCC 16872, Aspergillus aculeatus ATCC 16872

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L9WEP4	A0A1L9WH75	A0A1L9WEP4	A0A1L9WH75	Uncharacterized protein; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.631
A0A1L9WEP4	A0A1L9WKQ9	A0A1L9WEP4	A0A1L9WKQ9	Uncharacterized protein; Belongs to the DEAD box helicase family.	Brix domain-containing protein.	0.653
A0A1L9WEP4	A0A1L9WLJ6	A0A1L9WEP4	A0A1L9WLJ6	Uncharacterized protein; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.874
A0A1L9WEP4	A0A1L9WM65	A0A1L9WEP4	A0A1L9WM65	Uncharacterized protein; Belongs to the DEAD box helicase family.	Protein MAK16; Belongs to the MAK16 family.	0.829
A0A1L9WEP4	A0A1L9WMT7	A0A1L9WEP4	A0A1L9WMT7	Uncharacterized protein; Belongs to the DEAD box helicase family.	Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family.	0.772
A0A1L9WEP4	A0A1L9WMX9	A0A1L9WEP4	A0A1L9WMX9	Uncharacterized protein; Belongs to the DEAD box helicase family.	60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family.	0.791
A0A1L9WEP4	A0A1L9WPG5	A0A1L9WEP4	A0A1L9WPG5	Uncharacterized protein; Belongs to the DEAD box helicase family.	C2H2-type domain-containing protein.	0.678
A0A1L9WEP4	A0A1L9WSC9	A0A1L9WEP4	A0A1L9WSC9	Uncharacterized protein; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.946
A0A1L9WEP4	A0A1L9WTX8	A0A1L9WEP4	A0A1L9WTX8	Uncharacterized protein; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.834
A0A1L9WEP4	A0A1L9WVR5	A0A1L9WEP4	A0A1L9WVR5	Uncharacterized protein; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.667
A0A1L9WEP4	A0A1L9WW37	A0A1L9WEP4	A0A1L9WW37	Uncharacterized protein; Belongs to the DEAD box helicase family.	PUM-HD domain-containing protein.	0.838
A0A1L9WEP4	A0A1L9WWS6	A0A1L9WEP4	A0A1L9WWS6	Uncharacterized protein; Belongs to the DEAD box helicase family.	CP-type G domain-containing protein.	0.964
A0A1L9WEP4	A0A1L9WY59	A0A1L9WEP4	A0A1L9WY59	Uncharacterized protein; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.754
A0A1L9WEP4	A0A1L9WYF9	A0A1L9WEP4	A0A1L9WYF9	Uncharacterized protein; Belongs to the DEAD box helicase family.	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.	0.916
A0A1L9WEP4	A0A1L9WYM7	A0A1L9WEP4	A0A1L9WYM7	Uncharacterized protein; Belongs to the DEAD box helicase family.	Brix domain-containing protein.	0.754
A0A1L9WEP4	A0A1L9X370	A0A1L9WEP4	A0A1L9X370	Uncharacterized protein; Belongs to the DEAD box helicase family.	Brix domain-containing protein.	0.758
A0A1L9WEP4	A0A1L9X387	A0A1L9WEP4	A0A1L9X387	Uncharacterized protein; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.534
A0A1L9WEP4	A0A1L9X6J4	A0A1L9WEP4	A0A1L9X6J4	Uncharacterized protein; Belongs to the DEAD box helicase family.	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	0.943
A0A1L9WEP4	A0A1L9X804	A0A1L9WEP4	A0A1L9X804	Uncharacterized protein; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.731
A0A1L9WEP4	A0A1L9X893	A0A1L9WEP4	A0A1L9X893	Uncharacterized protein; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.842