STRINGSTRING
MCM7 MCM7 A0A1L9WZD4 A0A1L9WZD4 A0A1L9WWY9 A0A1L9WWY9 A0A1L9WLS2 A0A1L9WLS2 A0A1L9WK66 A0A1L9WK66 A0A1L9WH42 A0A1L9WH42 A0A1L9WH14 A0A1L9WH14 A0A1L9WGR4 A0A1L9WGR4 A0A1L9WGL2 A0A1L9WGL2 A0A1L9WEP1 A0A1L9WEP1 A0A1L9WXC1 A0A1L9WXC1 A0A1L9XAD4 A0A1L9XAD4 A0A1L9X9V7 A0A1L9X9V7 A0A1L9X8V5 A0A1L9X8V5 A0A1L9X8F3 A0A1L9X8F3 A0A1L9X8E5 A0A1L9X8E5 A0A1L9X891 A0A1L9X891 A0A1L9X7S0 A0A1L9X7S0 A0A1L9X7R9 A0A1L9X7R9 A0A1L9X7A3 A0A1L9X7A3 A0A1L9X6Z7 A0A1L9X6Z7 A0A1L9X5W9 A0A1L9X5W9 A0A1L9X5K8 A0A1L9X5K8 A0A1L9WXW8 A0A1L9WXW8 A0A1L9WXZ5 A0A1L9WXZ5 A0A1L9WY17 A0A1L9WY17 A0A1L9WY36 A0A1L9WY36 A0A1L9WY58 A0A1L9WY58 A0A1L9WWW9 A0A1L9WWW9 A0A1L9WZM6 A0A1L9WZM6 A0A1L9X026 A0A1L9X026 A0A1L9X1Y7 A0A1L9X1Y7 A0A1L9X208 A0A1L9X208 A0A1L9X2Q7 A0A1L9X2Q7 A0A1L9X513 A0A1L9X513 A0A1L9WLZ3 A0A1L9WLZ3 A0A1L9WM09 A0A1L9WM09 A0A1L9WME8 A0A1L9WME8 A0A1L9WNW4 A0A1L9WNW4 A0A1L9WRF8 A0A1L9WRF8 A0A1L9WRI3 A0A1L9WRI3 A0A1L9WT69 A0A1L9WT69 A0A1L9WTD3 A0A1L9WTD3 A0A1L9WW07 A0A1L9WW07 A0A1L9WW34 A0A1L9WW34 A0A1L9WWJ1 A0A1L9WWJ1 A0A1L9WWL5 A0A1L9WWL5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (805 aa)
A0A1L9WZD4Uncharacterized protein. (855 aa)
A0A1L9WWY9H15 domain-containing protein. (219 aa)
A0A1L9WLS2Telo_bind domain-containing protein. (621 aa)
A0A1L9WK66Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
A0A1L9WH42Uncharacterized protein. (821 aa)
A0A1L9WH14DNA helicase; Belongs to the MCM family. (897 aa)
A0A1L9WGR4Uncharacterized protein. (163 aa)
A0A1L9WGL2Uncharacterized protein. (577 aa)
A0A1L9WEP1Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (605 aa)
A0A1L9WXC1J domain-containing protein. (324 aa)
A0A1L9XAD4Cell division control protein; Belongs to the CDC6/cdc18 family. (641 aa)
A0A1L9X9V7TFIIB-type domain-containing protein. (345 aa)
A0A1L9X8V5Histone H2A; Belongs to the histone H2A family. (138 aa)
A0A1L9X8F3Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
A0A1L9X8E5Histone H3; Belongs to the histone H3 family. (136 aa)
A0A1L9X891RPA_C domain-containing protein. (268 aa)
A0A1L9X7S0Uncharacterized protein. (476 aa)
A0A1L9X7R9Uncharacterized protein. (871 aa)
A0A1L9X7A3Cnn_1N domain-containing protein. (962 aa)
A0A1L9X6Z7Sld5 domain-containing protein. (178 aa)
A0A1L9X5W9Uncharacterized protein. (542 aa)
A0A1L9X5K8DNA polymerase. (1464 aa)
A0A1L9WXW8AAA_16 domain-containing protein. (565 aa)
A0A1L9WXZ5MPN domain-containing protein. (697 aa)
A0A1L9WY17Stn1 domain-containing protein. (303 aa)
A0A1L9WY36Uncharacterized protein. (368 aa)
A0A1L9WY58DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (500 aa)
A0A1L9WWW9CENP-T_C domain-containing protein. (428 aa)
A0A1L9WZM6DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (657 aa)
A0A1L9X026DNA helicase; Belongs to the MCM family. (961 aa)
A0A1L9X1Y7ENDO3c domain-containing protein. (402 aa)
A0A1L9X208AAA domain-containing protein. (755 aa)
A0A1L9X2Q7DNA helicase; Belongs to the MCM family. (883 aa)
A0A1L9X513DNA helicase; Belongs to the MCM family. (1026 aa)
A0A1L9WLZ3Uncharacterized protein. (430 aa)
A0A1L9WM09DNA polymerase. (1106 aa)
A0A1L9WME8Histone domain-containing protein. (195 aa)
A0A1L9WNW4Sld5 domain-containing protein. (226 aa)
A0A1L9WRF8Uncharacterized protein; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (96 aa)
A0A1L9WRI3Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (516 aa)
A0A1L9WT69DNA primase; Belongs to the eukaryotic-type primase small subunit family. (518 aa)
A0A1L9WTD3ORC_WH_C domain-containing protein. (698 aa)
A0A1L9WW07SLD3 domain-containing protein. (1014 aa)
A0A1L9WW34DNA helicase; Belongs to the MCM family. (720 aa)
A0A1L9WWJ1Histone H2A; Belongs to the histone H2A family. (134 aa)
A0A1L9WWL5Histone H2B; Belongs to the histone H2B family. (140 aa)
Your Current Organism:
Aspergillus aculeatus
NCBI taxonomy Id: 690307
Other names: A. aculeatus ATCC 16872, Aspergillus aculeatus ATCC 16872
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