STRINGSTRING
pdxA pdxA murB murB mdh mdh AEG50532.1 AEG50532.1 AEG51481.1 AEG51481.1 AEG51430.1 AEG51430.1 AEG48673.1 AEG48673.1 AEG51422.1 AEG51422.1 AEG48582.1 AEG48582.1 AEG48380.1 AEG48380.1 AEG48377.1 AEG48377.1 AEG51414.1 AEG51414.1 AEG51379.1 AEG51379.1 AEG51232.1 AEG51232.1 AEG51230.1 AEG51230.1 AEG51077.1 AEG51077.1 AEG51058.1 AEG51058.1 AEG48337.1 AEG48337.1 AEG48297.1 AEG48297.1 ilvC ilvC AEG48090.1 AEG48090.1 AEG48088.1 AEG48088.1 leuB leuB AEG47881.1 AEG47881.1 AEG47803.1 AEG47803.1 AEG50986.1 AEG50986.1 leuB-2 leuB-2 AEG50561.1 AEG50561.1 AEG50514.1 AEG50514.1 AEG50334.1 AEG50334.1 hisD hisD AEG50032.1 AEG50032.1 AEG50009.1 AEG50009.1 gpsA gpsA AEG49926.1 AEG49926.1 aroE aroE AEG49866.1 AEG49866.1 AEG49784.1 AEG49784.1 AEG49722.1 AEG49722.1 AEG49643.1 AEG49643.1 guaB guaB AEG49031.1 AEG49031.1 dxr dxr AEG48909.1 AEG48909.1 AEG48840.1 AEG48840.1 zwf zwf AEG48771.1 AEG48771.1 AEG48764.1 AEG48764.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
Predicted Interactions
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pdxA4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (331 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (311 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa)
AEG50532.1KEGG: sjp:SJA_C1-07510 hypothetical protein. (61 aa)
AEG51481.1Oxidoreductase domain protein; PFAM: Oxidoreductase, N-terminal; KEGG: nar:Saro_2811 oxidoreductase-like. (313 aa)
AEG51430.1KEGG: nar:Saro_2504 alcohol dehydrogenase, zinc-containing; PFAM: Alcohol dehydrogenase, zinc-binding; Alcohol dehydrogenase GroES-like. (370 aa)
AEG48673.1TIGRFAM: Nucleotide sugar dehydrogenase; KEGG: sjp:SJA_C1-19330 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase, C-terminal. (447 aa)
AEG51422.1PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, zinc-binding; KEGG: pzu:PHZ_c0845 alcohol dehydrogenase class III. (366 aa)
AEG48582.1KEGG: nar:Saro_3463 alcohol dehydrogenase; TIGRFAM: Alcohol dehydrogenase, zinc-binding type 2; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, zinc-binding. (335 aa)
AEG48380.12-dehydropantoate 2-reductase; TIGRFAM: Ketopantoate reductase ApbA/PanE; KEGG: sjp:SJA_C2-03560 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE, C-terminal; Ketopantoate reductase ApbA/PanE, N-terminal. (328 aa)
AEG48377.1KEGG: sjp:SJA_C2-03590 2-hydroxy-3-oxopropionate reductase; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding. (297 aa)
AEG51414.13-alpha,7-alpha, 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoAhydratase; KEGG: pzu:PHZ_c2527 acyl dehydratase; PFAM: MaoC-like dehydratase. (308 aa)
AEG51379.1KEGG: sjp:SJA_C2-04960 putative aryl-alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, zinc-binding; Alcohol dehydrogenase GroES-like. (366 aa)
AEG51232.13-hydroxybutyryl-CoA epimerase; KEGG: swi:Swit_0322 3-hydroxyacyl-CoA dehydrogenase. (703 aa)
AEG51230.1KEGG: swi:Swit_0320 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; 3-hydroxyacyl-CoA dehydrogenase, C-terminal. (320 aa)
AEG51077.1KEGG: rpt:Rpal_2166 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; TIGRFAM: Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase; PFAM: Alcohol dehydrogenase, zinc-binding; Alcohol dehydrogenase GroES-like; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (370 aa)
AEG51058.1KEGG: sjp:SJA_C2-05100 putative alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, zinc-binding. (377 aa)
AEG48337.1PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; KEGG: sjp:SJA_C1-21620 malate dehydrogenase. (755 aa)
AEG48297.13-hydroxybutyryl-CoA epimerase; KEGG: cse:Cseg_0771 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; Crotonase, core; 3-hydroxyacyl-CoA dehydrogenase, C-terminal; Belongs to the enoyl-CoA hydratase/isomerase family. (690 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa)
AEG48090.1TIGRFAM: Nucleotide sugar dehydrogenase; KEGG: sjp:SJA_C1-22180 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase, C-terminal; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (431 aa)
AEG48088.1TIGRFAM: Nucleotide sugar dehydrogenase; KEGG: sjp:SJA_C1-22200 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase, C-terminal. (439 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (348 aa)
AEG47881.13-hydroxybutyryl-CoA epimerase; KEGG: cak:Caul_0125 3-hydroxyacyl-CoA dehydrogenase NAD-binding; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; Crotonase, core; 3-hydroxyacyl-CoA dehydrogenase, C-terminal. (713 aa)
AEG47803.13-hydroxybutyryl-CoA epimerase; KEGG: sal:Sala_3068 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; Crotonase, core; 3-hydroxyacyl-CoA dehydrogenase, C-terminal; Belongs to the enoyl-CoA hydratase/isomerase family. (680 aa)
AEG50986.13-hydroxybutyryl-CoA epimerase; KEGG: sjp:SJA_C1-03820 3-hydroxyacyl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; Crotonase, core; 3-hydroxyacyl-CoA dehydrogenase, C-terminal; Belongs to the enoyl-CoA hydratase/isomerase family. (685 aa)
leuB-23-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (373 aa)
AEG50561.1KEGG: bpt:Bpet2258 putative beta-hydroxyacid dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding. (293 aa)
AEG50514.1PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; KEGG: sjp:SJA_C1-07280 homoserine dehydrogenase. (434 aa)
AEG50334.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (285 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (429 aa)
AEG50032.1TIGRFAM: Riboflavin biosynthesis protein RibD; KEGG: sjp:SJA_C1-02910 5-amino-6-(5-phosphoribosylamino)uracil reductase; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal; CMP/dCMP deaminase, zinc-binding. (317 aa)
AEG50009.1Glyoxylate reductase; KEGG: sjp:SJA_C1-01220 putative dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region. (322 aa)
gpsAKEGG: sjp:SJA_C1-03140 glycerol-3-phosphate dehydrogenase (NAD(P)+); HAMAP: Glycerol-3-phosphate dehydrogenase [NAD(P)+]; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal; NAD-dependent glycerol-3-phosphate dehydrogenase, C-terminal; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (328 aa)
AEG49926.1Glyoxylate reductase; KEGG: sjp:SJA_C1-00190 putative dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region. (310 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (273 aa)
AEG49866.1PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; KEGG: sjp:SJA_C1-35000 malate dehydrogenase. (753 aa)
AEG49784.13-hydroxybutyryl-CoA epimerase; KEGG: hoh:Hoch_2339 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; Crotonase, core; 3-hydroxyacyl-CoA dehydrogenase, C-terminal; Belongs to the enoyl-CoA hydratase/isomerase family. (687 aa)
AEG49722.1KEGG: sjp:SJA_C1-34150 3-hydroxybutyryl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; 3-hydroxyacyl-CoA dehydrogenase, C-terminal. (292 aa)
AEG49643.1TIGRFAM: D-3-phosphoglycerate dehydrogenase; KEGG: sjp:SJA_C1-01840 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; Amino acid-binding ACT. (526 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (485 aa)
AEG49031.1Isocitrate dehydrogenase, NADP-dependent; KEGG: sjp:SJA_C1-24210 isocitrate dehydrogenase; TIGRFAM: Isocitrate dehydrogenase NADP-dependent, eukaryotic; PFAM: Isocitrate/isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (406 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (385 aa)
AEG48909.1KEGG: sjp:SJA_C1-15190 3-hydroxyisobutyrate dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding. (289 aa)
AEG48840.1KEGG: sjp:SJA_C1-23240 glyoxylate reductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region. (332 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (486 aa)
AEG48771.13-hydroxybutyryl-CoA epimerase; KEGG: sjp:SJA_C1-20800 3-hydroxyacyl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; Crotonase, core; 3-hydroxyacyl-CoA dehydrogenase, C-terminal. (725 aa)
AEG48764.1TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; KEGG: sjp:SJA_C1-20720 3-hydroxyisobutyrate dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; Belongs to the HIBADH-related family. (294 aa)
Your Current Organism:
Sphingobium chlorophenolicum
NCBI taxonomy Id: 690566
Other names: FLAVOBACTERIUM SP. (STRAIN ATCC 39723), Flavobacterium sp. (ATCC 39723), Flavobacterium sp. ATCC 39723, S. chlorophenolicum L-1, Sphingobium chlorophenolicum ATCC 39723, Sphingobium chlorophenolicum L-1, Sphingobium chlorophenolicum str. L-1, Sphingobium chlorophenolicum strain L-1
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