(14 nodes) Citrate cycle (TCA cycle), and Novobiocin biosynthesis network (Desulfocurvibacter africanus)

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Your Input:
	ldh	L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (328 aa)
	Desaf_0973	Aspartate transaminase; KEGG: dvm:DvMF_2204 aminotransferase class I and II; PFAM: Aminotransferase, class I/II. (391 aa)
	Desaf_1085	PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: dsa:Desal_3826 4Fe-4S ferredoxin iron-sulfur binding domain protein. (82 aa)
	Desaf_1086	3-methyl-2-oxobutanoate dehydrogenase (ferredoxin); KEGG: dsa:Desal_3825 2-ketoisovalerate ferredoxin reductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal. (358 aa)
	Desaf_1087	2-oxoglutarate synthase; KEGG: drt:Dret_0090 thiamine pyrophosphate protein domain protein TPP-binding; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding protein. (255 aa)
	Desaf_1088	PFAM: Pyruvate/ketoisovalerate oxidoreductase; KEGG: dvl:Dvul_0047 pyruvate ferredoxin/flavodoxin oxidoreductase. (180 aa)
	Desaf_1541	TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; KEGG: pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase. (564 aa)
	Desaf_1542	TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate; KEGG: dde:Dde_1793 2-oxoacid:acceptor oxidoreductase subunit beta, pyruvate/2-ketoisovalerate; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding protein. (295 aa)
	Desaf_1752	Aspartate transaminase; KEGG: class I/II aminotransferase; PFAM: Aminotransferase, class I/II. (394 aa)
	Desaf_2186	TIGRFAM: Pyruvate-flavodoxin oxidoreductase; KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding protein. (1232 aa)
	Desaf_3714	2-oxoglutarate synthase; KEGG: dsa:Desal_1529 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: Pyruvate/ketoisovalerate oxidoreductase. (209 aa)
	Desaf_3715	KEGG: dma:DMR_18780 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding protein. (279 aa)
	Desaf_3716	2-oxoglutarate synthase; KEGG: pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal. (383 aa)
	Desaf_3717	PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: dvm:DvMF_0602 4Fe-4S ferredoxin iron-sulfur binding domain protein. (108 aa)

Your Current Organism:

Desulfocurvibacter africanus

NCBI taxonomy Id: 690850
Other names: D. africanus subsp. africanus str. Walvis Bay, Desulfocurvibacter africanus str. Walvis Bay, Desulfocurvibacter africanus subsp. africanus str. Walvis Bay, Desulfovibrio africanus ATCC 19997, Desulfovibrio africanus str. Walvis Bay, Desulfovibrio africanus strain Walvis Bay

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Desaf_0973	Desaf_1085	Desaf_0973	Desaf_1085	Aspartate transaminase; KEGG: dvm:DvMF_2204 aminotransferase class I and II; PFAM: Aminotransferase, class I/II.	PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: dsa:Desal_3826 4Fe-4S ferredoxin iron-sulfur binding domain protein.	0.612
Desaf_0973	Desaf_1086	Desaf_0973	Desaf_1086	Aspartate transaminase; KEGG: dvm:DvMF_2204 aminotransferase class I and II; PFAM: Aminotransferase, class I/II.	3-methyl-2-oxobutanoate dehydrogenase (ferredoxin); KEGG: dsa:Desal_3825 2-ketoisovalerate ferredoxin reductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal.	0.809
Desaf_0973	Desaf_1087	Desaf_0973	Desaf_1087	Aspartate transaminase; KEGG: dvm:DvMF_2204 aminotransferase class I and II; PFAM: Aminotransferase, class I/II.	2-oxoglutarate synthase; KEGG: drt:Dret_0090 thiamine pyrophosphate protein domain protein TPP-binding; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding protein.	0.804
Desaf_0973	Desaf_1088	Desaf_0973	Desaf_1088	Aspartate transaminase; KEGG: dvm:DvMF_2204 aminotransferase class I and II; PFAM: Aminotransferase, class I/II.	PFAM: Pyruvate/ketoisovalerate oxidoreductase; KEGG: dvl:Dvul_0047 pyruvate ferredoxin/flavodoxin oxidoreductase.	0.608
Desaf_0973	Desaf_1541	Desaf_0973	Desaf_1541	Aspartate transaminase; KEGG: dvm:DvMF_2204 aminotransferase class I and II; PFAM: Aminotransferase, class I/II.	TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; KEGG: pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase.	0.830
Desaf_0973	Desaf_1542	Desaf_0973	Desaf_1542	Aspartate transaminase; KEGG: dvm:DvMF_2204 aminotransferase class I and II; PFAM: Aminotransferase, class I/II.	TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate; KEGG: dde:Dde_1793 2-oxoacid:acceptor oxidoreductase subunit beta, pyruvate/2-ketoisovalerate; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding protein.	0.804
Desaf_0973	Desaf_1752	Desaf_0973	Desaf_1752	Aspartate transaminase; KEGG: dvm:DvMF_2204 aminotransferase class I and II; PFAM: Aminotransferase, class I/II.	Aspartate transaminase; KEGG: class I/II aminotransferase; PFAM: Aminotransferase, class I/II.	0.919
Desaf_0973	Desaf_2186	Desaf_0973	Desaf_2186	Aspartate transaminase; KEGG: dvm:DvMF_2204 aminotransferase class I and II; PFAM: Aminotransferase, class I/II.	TIGRFAM: Pyruvate-flavodoxin oxidoreductase; KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding protein.	0.423
Desaf_0973	Desaf_3714	Desaf_0973	Desaf_3714	Aspartate transaminase; KEGG: dvm:DvMF_2204 aminotransferase class I and II; PFAM: Aminotransferase, class I/II.	2-oxoglutarate synthase; KEGG: dsa:Desal_1529 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: Pyruvate/ketoisovalerate oxidoreductase.	0.608
Desaf_0973	Desaf_3715	Desaf_0973	Desaf_3715	Aspartate transaminase; KEGG: dvm:DvMF_2204 aminotransferase class I and II; PFAM: Aminotransferase, class I/II.	KEGG: dma:DMR_18780 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding protein.	0.804
Desaf_0973	Desaf_3716	Desaf_0973	Desaf_3716	Aspartate transaminase; KEGG: dvm:DvMF_2204 aminotransferase class I and II; PFAM: Aminotransferase, class I/II.	2-oxoglutarate synthase; KEGG: pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal.	0.809
Desaf_0973	Desaf_3717	Desaf_0973	Desaf_3717	Aspartate transaminase; KEGG: dvm:DvMF_2204 aminotransferase class I and II; PFAM: Aminotransferase, class I/II.	PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: dvm:DvMF_0602 4Fe-4S ferredoxin iron-sulfur binding domain protein.	0.612
Desaf_0973	ldh	Desaf_0973	Desaf_0594	Aspartate transaminase; KEGG: dvm:DvMF_2204 aminotransferase class I and II; PFAM: Aminotransferase, class I/II.	L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.	0.921
Desaf_1085	Desaf_0973	Desaf_1085	Desaf_0973	PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: dsa:Desal_3826 4Fe-4S ferredoxin iron-sulfur binding domain protein.	Aspartate transaminase; KEGG: dvm:DvMF_2204 aminotransferase class I and II; PFAM: Aminotransferase, class I/II.	0.612
Desaf_1085	Desaf_1086	Desaf_1085	Desaf_1086	PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: dsa:Desal_3826 4Fe-4S ferredoxin iron-sulfur binding domain protein.	3-methyl-2-oxobutanoate dehydrogenase (ferredoxin); KEGG: dsa:Desal_3825 2-ketoisovalerate ferredoxin reductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal.	0.999
Desaf_1085	Desaf_1087	Desaf_1085	Desaf_1087	PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: dsa:Desal_3826 4Fe-4S ferredoxin iron-sulfur binding domain protein.	2-oxoglutarate synthase; KEGG: drt:Dret_0090 thiamine pyrophosphate protein domain protein TPP-binding; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding protein.	0.998
Desaf_1085	Desaf_1088	Desaf_1085	Desaf_1088	PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: dsa:Desal_3826 4Fe-4S ferredoxin iron-sulfur binding domain protein.	PFAM: Pyruvate/ketoisovalerate oxidoreductase; KEGG: dvl:Dvul_0047 pyruvate ferredoxin/flavodoxin oxidoreductase.	0.998
Desaf_1085	Desaf_1541	Desaf_1085	Desaf_1541	PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: dsa:Desal_3826 4Fe-4S ferredoxin iron-sulfur binding domain protein.	TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; KEGG: pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase.	0.976
Desaf_1085	Desaf_1542	Desaf_1085	Desaf_1542	PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: dsa:Desal_3826 4Fe-4S ferredoxin iron-sulfur binding domain protein.	TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate; KEGG: dde:Dde_1793 2-oxoacid:acceptor oxidoreductase subunit beta, pyruvate/2-ketoisovalerate; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding protein.	0.957
Desaf_1085	Desaf_1752	Desaf_1085	Desaf_1752	PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: dsa:Desal_3826 4Fe-4S ferredoxin iron-sulfur binding domain protein.	Aspartate transaminase; KEGG: class I/II aminotransferase; PFAM: Aminotransferase, class I/II.	0.612

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