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Desaf_0310 Desaf_0310 Desaf_0346 Desaf_0346 Desaf_0481 Desaf_0481 Desaf_0487 Desaf_0487 gmhA gmhA Desaf_0636 Desaf_0636 fcl fcl Desaf_0924 Desaf_0924 Desaf_1012 Desaf_1012 Desaf_1015 Desaf_1015 truA truA queA queA Desaf_1100 Desaf_1100 pgi pgi gyrB gyrB gyrA gyrA Desaf_1200 Desaf_1200 dapF dapF topA topA Desaf_1363 Desaf_1363 Desaf_1382 Desaf_1382 hldD hldD trpF trpF Desaf_1512 Desaf_1512 glmS glmS Desaf_1653 Desaf_1653 hemL hemL Desaf_1824 Desaf_1824 trpF-2 trpF-2 Desaf_1879 Desaf_1879 Desaf_1996 Desaf_1996 Desaf_2092 Desaf_2092 Desaf_2305 Desaf_2305 Desaf_2414 Desaf_2414 Desaf_2456 Desaf_2456 Desaf_2640 Desaf_2640 nnrE nnrE Desaf_2729 Desaf_2729 Desaf_2730 Desaf_2730 Desaf_2781 Desaf_2781 tig tig Desaf_2794 Desaf_2794 Desaf_2828 Desaf_2828 mtnA mtnA Desaf_2930 Desaf_2930 Desaf_2975 Desaf_2975 Desaf_3019 Desaf_3019 Desaf_3055 Desaf_3055 tpiA tpiA Desaf_3114 Desaf_3114 Desaf_3196 Desaf_3196 coaE coaE hisA hisA glmM glmM gpmI gpmI murI murI Desaf_3723 Desaf_3723 truB truB groL groL Desaf_0110 Desaf_0110 Desaf_0178 Desaf_0178 Desaf_0189 Desaf_0189 gpmA gpmA purE purE tal tal rpiA rpiA
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Desaf_0310KEGG: met:M446_5045 putative DNA topoisomerase I; manually curated. (369 aa)
Desaf_0346PFAM: Peptidyl-prolyl cis-trans isomerase, PpiC-type; KEGG: drt:Dret_1772 PpiC-type peptidyl-prolyl cis-trans isomerase. (631 aa)
Desaf_0481dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (181 aa)
Desaf_0487KEGG: tra:Trad_0749 phosphoglucomutase, alpha-D-glucose phosphate-specific; TIGRFAM: Phosphoglucomutase, alpha-D-glucose specific; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, C-terminal. (550 aa)
gmhAPhosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (205 aa)
Desaf_0636PFAM: DSBA oxidoreductase; KEGG: bba:Bd0789 disulfide interchange protein. (264 aa)
fclGDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (316 aa)
Desaf_0924PFAM: Protein of unknown function DUF1565; KEGG: npu:Npun_F1899 hypothetical protein. (546 aa)
Desaf_1012PFAM: NAD-dependent epimerase/dehydratase; KEGG: dba:Dbac_0489 UDP-glucose 4-epimerase. (78 aa)
Desaf_1015dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (177 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (266 aa)
queAS-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (363 aa)
Desaf_1100Fructose-2,6-bisphosphate 2-phosphatase; KEGG: dde:Dde_0511 6-phosphofructo-2-kinase; PFAM: Phosphoglycerate mutase; 6-phosphofructo-2-kinase. (405 aa)
pgiHAMAP: Phosphoglucose isomerase (PGI); KEGG: tgr:Tgr7_0871 glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase (PGI); Belongs to the GPI family. (547 aa)
gyrBDNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (807 aa)
gyrADNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (827 aa)
Desaf_1200KEGG: RluA family pseudouridine synthase; TIGRFAM: Pseudouridine synthase, RluC/RluD; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; Belongs to the pseudouridine synthase RluA family. (297 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (282 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (766 aa)
Desaf_1363PFAM: Myo-inositol-1-phosphate synthase; Myo-inositol-1-phosphate synthase, GAPDH-like; KEGG: mem:Memar_0974 myo-inositol-1-phosphate synthase. (367 aa)
Desaf_1382TIGRFAM: Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: gem:GM21_2590 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type II, C-terminal; Nucleotidyl transferase. (534 aa)
hldDADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (328 aa)
trpFKEGG: drt:Dret_0255 N-(5'phosphoribosyl)anthranilate isomerase (PRAI); PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); Belongs to the TrpF family. (246 aa)
Desaf_1512KEGG: afw:Anae109_3098 4-oxalocrotonate tautomerase; TIGRFAM: 4-oxalocrotonate tautomerase, subgroup; PFAM: 4-oxalocrotonate tautomerase. (67 aa)
glmSGlucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (608 aa)
Desaf_1653PFAM: Peptidyl-prolyl cis-trans isomerase, FKBP-type; KEGG: mem:Memar_1765 peptidylprolyl isomerase, FKBP-type. (144 aa)
hemLGlutamate-1-semialdehyde 2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; HAMAP: Glutamate-1-semialdehyde 2,1-aminomutase; KEGG: dba:Dbac_3003 glutamate-1-semialdehyde-2,1-aminomutase. (423 aa)
Desaf_1824Hypothetical protein; KEGG: dinitrogenase iron-molybdenum cofactor biosynthesis protein. (147 aa)
trpF-2PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: dma:DMR_05270 N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (207 aa)
Desaf_1879Chorismate mutase; KEGG: dvm:DvMF_1749 prephenate dehydratase; TIGRFAM: Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain; PFAM: Prephenate dehydratase; Chorismate mutase, type II; Amino acid-binding ACT. (429 aa)
Desaf_1996KEGG: dma:DMR_04970 hypothetical protein. (186 aa)
Desaf_2092Sugar-phosphate isomerase, RpiB/LacA/LacB family; TIGRFAM: Ribose/galactose isomerase; Ribose 5-phosphate isomerase B; KEGG: dma:DMR_21090 ribose-5-phosphate isomerase B; PFAM: Ribose/galactose isomerase. (152 aa)
Desaf_2305TIGRFAM: UDP-glucose 4-epimerase; KEGG: cyc:PCC7424_4242 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (326 aa)
Desaf_2414PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, C-terminal; KEGG: dma:DMR_27100 phosphohexose mutase. (464 aa)
Desaf_2456PFAM: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: dma:DMR_21140 thioredoxin-related domain protein. (157 aa)
Desaf_2640TIGRFAM: Ribulose-phosphate 3-epimerase; KEGG: dsa:Desal_1238 ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (240 aa)
nnrEYjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] (520 aa)
Desaf_2729KEGG: hypothetical protein. (374 aa)
Desaf_2730SurA domain-containing protein; PFAM: SurA N-terminal; Peptidyl-prolyl cis-trans isomerase, PpiC-type; KEGG: drt:Dret_1690 SurA domain protein. (334 aa)
Desaf_2781Sugar kinase; KEGG: sfu:Sfum_3171 sugar kinase. (285 aa)
tigTrigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (439 aa)
Desaf_2794Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (196 aa)
Desaf_2828TIGRFAM: Homoserine kinase, putative; Cofactor-independent phosphoglycerate mutase, archaeal; KEGG: proposed homoserine kinase; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Metalloenzyme. (399 aa)
mtnAMethylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (347 aa)
Desaf_2930Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (379 aa)
Desaf_2975Trehalose synthase; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region; TIGRFAM: Trehalose synthase/alpha-amylase, N-terminal; Trehalose synthase/probable maltokinase, C-terminal; KEGG: cag:Cagg_2090 trehalose synthase; PFAM: Glycosyl hydrolase, family 13, catalytic region; Aminoglycoside phosphotransferase. (1102 aa)
Desaf_3019TIGRFAM: Pseudouridine synthase, RsuA and RluB/E/F; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; KEGG: dde:Dde_1958 pseudouridine synthase, Rsu; SMART: RNA-binding S4; Belongs to the pseudouridine synthase RsuA family. (254 aa)
Desaf_3055PFAM: Phosphoglycerate mutase; KEGG: dde:Dde_0736 phosphoglycerate mutase-like protein. (205 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
Desaf_3114Thioredoxin; KEGG: drt:Dret_1908 thioredoxin; TIGRFAM: Thioredoxin; PFAM: Thioredoxin domain; Belongs to the thioredoxin family. (107 aa)
Desaf_3196PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; KEGG: pseudouridine synthase; Belongs to the pseudouridine synthase RluA family. (278 aa)
coaEDephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (556 aa)
hisAPFAM: Histidine biosynthesis; TIGRFAM: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; HAMAP: 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; KEGG: dsa:Desal_1557 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (242 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (450 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (525 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (282 aa)
Desaf_3723Precorrin-8X methylmutase CbiC/CobH; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; KEGG: precorrin-8X methylmutase. (243 aa)
truBtRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (308 aa)
groL60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (549 aa)
Desaf_0110KpsF/GutQ family protein; SMART: Cystathionine beta-synthase, core; TIGRFAM: KpsF/GutQ; KEGG: drt:Dret_0322 KpsF/GutQ family protein; PFAM: Sugar isomerase (SIS); Cystathionine beta-synthase, core; Belongs to the SIS family. GutQ/KpsF subfamily. (330 aa)
Desaf_0178Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (169 aa)
Desaf_0189TIGRFAM: Hopene cyclase; Squalene cyclase; KEGG: gme:Gmet_0419 terpene synthase:squalene cyclase; PFAM: Prenyltransferase/squalene oxidase. (687 aa)
gpmA2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (247 aa)
purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (164 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (367 aa)
rpiARibose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (246 aa)
Your Current Organism:
Desulfocurvibacter africanus
NCBI taxonomy Id: 690850
Other names: D. africanus subsp. africanus str. Walvis Bay, Desulfocurvibacter africanus str. Walvis Bay, Desulfocurvibacter africanus subsp. africanus str. Walvis Bay, Desulfovibrio africanus ATCC 19997, Desulfovibrio africanus str. Walvis Bay, Desulfovibrio africanus strain Walvis Bay
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