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Desaf_0014 Desaf_0014 Desaf_0314 Desaf_0314 Desaf_0337 Desaf_0337 Desaf_0345 Desaf_0345 Desaf_0390 Desaf_0390 Desaf_0419 Desaf_0419 Desaf_0420 Desaf_0420 Desaf_0450 Desaf_0450 Desaf_0535 Desaf_0535 Desaf_0536 Desaf_0536 Desaf_0580 Desaf_0580 Desaf_0581 Desaf_0581 Desaf_0584 Desaf_0584 Desaf_0585 Desaf_0585 Desaf_0653 Desaf_0653 Desaf_0904 Desaf_0904 Desaf_0946 Desaf_0946 Desaf_1287 Desaf_1287 Desaf_1384 Desaf_1384 Desaf_1387 Desaf_1387 Desaf_1388 Desaf_1388 Desaf_1468 Desaf_1468 Desaf_1469 Desaf_1469 Desaf_1480 Desaf_1480 Desaf_1481 Desaf_1481 Desaf_1487 Desaf_1487 Desaf_1488 Desaf_1488 Desaf_1489 Desaf_1489 Desaf_1519 Desaf_1519 Desaf_1604 Desaf_1604 Desaf_1614 Desaf_1614 nuoN nuoN Desaf_1616 Desaf_1616 Desaf_1617 Desaf_1617 Desaf_1619 Desaf_1619 nuoK nuoK Desaf_1622 Desaf_1622 nuoH nuoH Desaf_1628 Desaf_1628 Desaf_1686 Desaf_1686 Desaf_1688 Desaf_1688 rnfB rnfB glcB glcB Desaf_1748 Desaf_1748 ubiE ubiE Desaf_1770 Desaf_1770 Desaf_1800 Desaf_1800 Desaf_1801 Desaf_1801 Desaf_1863 Desaf_1863 Desaf_1866 Desaf_1866 Desaf_2139 Desaf_2139 Desaf_2182 Desaf_2182 Desaf_2316 Desaf_2316 Desaf_2383 Desaf_2383 Desaf_2499 Desaf_2499 Desaf_2509 Desaf_2509 Desaf_2750 Desaf_2750 Desaf_2830 Desaf_2830 Desaf_2881 Desaf_2881 Desaf_3077 Desaf_3077 Desaf_3127 Desaf_3127 Desaf_3128 Desaf_3128 Desaf_3130 Desaf_3130 Desaf_3131 Desaf_3131 sucD sucD Desaf_3550 Desaf_3550 Desaf_3633 Desaf_3633 Desaf_3634 Desaf_3634 Desaf_3637 Desaf_3637 Desaf_3699 Desaf_3699 Desaf_3700 Desaf_3700 Desaf_3701 Desaf_3701
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Desaf_0014Nitrate reductase; KEGG: dvl:Dvul_1523 molybdopterin oxidoreductase; PFAM: Molybdopterin oxidoreductase; Molybdopterin oxidoreductase Fe4S4 region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (640 aa)
Desaf_0314PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: dde:Dde_2944 iron-sulfur cluster-binding protein. (150 aa)
Desaf_0337PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; KEGG: dma:DMR_05410 quinone-interacting membrane-bound oxidoreductase complex subunit A. (413 aa)
Desaf_0345KEGG: dma:DMR_39020 aconitate hydratase; TIGRFAM: Aconitase, putative; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel. (641 aa)
Desaf_0390KEGG: dde:Dde_3211 split soret cytochrome c. (267 aa)
Desaf_0419Fe-S-cluster-containing hydrogenase component protein; KEGG: dsa:Desal_2658 FdhB2. (246 aa)
Desaf_0420Formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase; Molybdopterin oxidoreductase Fe4S4 region; Molydopterin dinucleotide-binding region; manually curated; Contains selenocysteine; KEGG: dsa:Desal_2659 formate dehydrogenase, alpha subunit; TIGRFAM: Formate dehydrogenase, alpha subunit, anaerobic; Twin-arginine translocation pathway, signal sequence. (1021 aa)
Desaf_0450PFAM: Cytochrome c, class III; KEGG: dba:Dbac_0567 cytochrome c class III. (127 aa)
Desaf_0535PFAM: Cytochrome bd ubiquinol oxidase, subunit I; KEGG: drt:Dret_0136 cytochrome bd ubiquinol oxidase subunit I. (435 aa)
Desaf_0536KEGG: cytochrome d ubiquinol oxidase subunit II; TIGRFAM: Cytochrome bd ubiquinol oxidase, subunit II; PFAM: Cytochrome bd ubiquinol oxidase, subunit II. (342 aa)
Desaf_0580PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: hypothetical protein. (140 aa)
Desaf_0581NADH dehydrogenase (quinone); KEGG: dsa:Desal_3237 NADH-ubiquinone oxidoreductase chain 49kDa; PFAM: NADH-quinone oxidoreductase, subunit D; Nickel-dependent hydrogenase, large subunit. (358 aa)
Desaf_0584PFAM: NADH:ubiquinone oxidoreductase, subunit 1; KEGG: dsa:Desal_3234 respiratory-chain NADH dehydrogenase subunit 1. (284 aa)
Desaf_0585NADH dehydrogenase (quinone); KEGG: dsa:Desal_3233 NADH/ubiquinone/plastoquinone (complex I); PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; NADH:ubiquinone oxidoreductase, chain 5/L, N-terminal. (636 aa)
Desaf_0653PFAM: Cytochrome c, class III; KEGG: dsa:Desal_2447 cytochrome c class III. (163 aa)
Desaf_0904Nitrate reductase; KEGG: dma:DMR_20480 molybdopterin oxidoreductase; PFAM: Molybdopterin oxidoreductase; Molybdopterin oxidoreductase Fe4S4 region; Molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (650 aa)
Desaf_0946KEGG: sse:Ssed_3758 hypothetical protein. (444 aa)
Desaf_1287KEGG: dvl:Dvul_0758 hypothetical protein. (384 aa)
Desaf_1384Hydrogen dehydrogenase; Contains selenocysteine; manually curated; KEGG: dly:Dehly_0726 nickel-dependent hydrogenase large subunit; PFAM: Nickel-dependent hydrogenase, large subunit. (488 aa)
Desaf_1387PFAM: FAD dependent oxidoreductase; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: dal:Dalk_4966 4Fe-4S ferredoxin iron-sulfur binding domain protein. (937 aa)
Desaf_1388PFAM: FAD dependent oxidoreductase; KEGG: dal:Dalk_5065 4Fe-4S ferredoxin, iron-sulfur binding domain protein. (57 aa)
Desaf_1468PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Twin-arginine translocation pathway, signal sequence, subgroup; KEGG: dol:Dole_0453 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein. (267 aa)
Desaf_1469PFAM: Polysulphide reductase, NrfD; KEGG: dsa:Desal_0182 polysulphide reductase NrfD. (385 aa)
Desaf_1480KEGG: drt:Dret_0165 iron-sulfur cluster-binding protein. (161 aa)
Desaf_1481KEGG: drt:Dret_0164 hypothetical protein. (335 aa)
Desaf_1487KEGG: cytochrome b/b6 domain-containing protein. (243 aa)
Desaf_1488PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: dsa:Desal_0372 4Fe-4S ferredoxin iron-sulfur binding domain protein. (263 aa)
Desaf_1489Nitrate reductase; KEGG: dde:Dde_0682 hypothetical protein; PFAM: Molybdopterin oxidoreductase; Molybdopterin oxidoreductase Fe4S4 region; Molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (730 aa)
Desaf_1519PFAM: Protein of unknown function DUF116; KEGG: drt:Dret_0017 protein of unknown function DUF116. (321 aa)
Desaf_1604PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Cysteine-rich region, CCG; KEGG: dma:DMR_07460 iron-sulfur binding protein. (397 aa)
Desaf_1614PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: dma:DMR_08240 iron-sulfur binding protein. (166 aa)
nuoNNAD(P)H-quinone oxidoreductase subunit 2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (490 aa)
Desaf_1616TIGRFAM: NADH-quinone oxidoreductase, chain M; KEGG: proton-translocating NADH-quinone oxidoreductase subunit M; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase. (523 aa)
Desaf_1617NADH dehydrogenase (quinone); KEGG: dsa:Desal_1499 putative monovalent cation/H+ antiporter subunit D; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase. (612 aa)
Desaf_1619NADH dehydrogenase (quinone); KEGG: dsa:Desal_1497 putative monovalent cation/H+ antiporter subunit D; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase. (493 aa)
nuoKNAD(P)H-quinone oxidoreductase subunit 4L; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (115 aa)
Desaf_1622PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: dsa:Desal_1494 4Fe-4S ferredoxin iron-sulfur binding domain protein. (224 aa)
nuoHNAD(P)H-quinone oxidoreductase subunit 1; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (328 aa)
Desaf_1628Nitrate reductase; KEGG: dba:Dbac_2860 molybdopterin oxidoreductase; PFAM: Molybdopterin oxidoreductase; Molybdopterin oxidoreductase Fe4S4 region; Molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (692 aa)
Desaf_1686PFAM: Fumarate reductase respiratory complex; KEGG: dsa:Desal_0720 fumarate reductase respiratory complex transmembrane subunit. (220 aa)
Desaf_1688KEGG: dsa:Desal_0722 fumarate reductase iron-sulfur subunit; TIGRFAM: Succinate dehydrogenase/fumarate reductase iron-sulphur protein. (244 aa)
rnfBElectron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. (698 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (723 aa)
Desaf_1748KEGG: dba:Dbac_0217 hydroxylamine oxidase. (526 aa)
ubiEUbiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (251 aa)
Desaf_1770PFAM: Cytochrome c, class III; KEGG: dsa:Desal_0756 cytochrome c class III. (140 aa)
Desaf_1800Formate dehydrogenase, alpha subunit; Contains selenocysteine; PFAM: Molybdopterin oxidoreductase; Molybdopterin oxidoreductase Fe4S4 region; Molydopterin dinucleotide-binding region; manually curated; Prodigal; KEGG: dba:Dbac_0971 formate dehydrogenase, alpha subunit; TIGRFAM: Formate dehydrogenase, alpha subunit, anaerobic; Twin-arginine translocation pathway, signal sequence; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1010 aa)
Desaf_1801KEGG: formate dehydrogenase subunit beta, FdhB2. (239 aa)
Desaf_1863Response regulator receiver protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Signal transduction response regulator, receiver region; KEGG: response regulator receiver. (1143 aa)
Desaf_1866PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: drt:Dret_0421 4Fe-4S ferredoxin iron-sulfur binding domain protein. (691 aa)
Desaf_2139PFAM: Nickel-dependent hydrogenase, large subunit; KEGG: hut:Huta_2605 nickel-dependent hydrogenase large subunit. (460 aa)
Desaf_2182Protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: Cysteine-rich region, CCG; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: hypothetical protein. (428 aa)
Desaf_2316KEGG: dba:Dbac_2336 formate dehydrogenase gamma subunit. (235 aa)
Desaf_2383PFAM: Metallophosphoesterase; KEGG: mes:Meso_2768 metallophosphoesterase. (234 aa)
Desaf_2499PFAM: Methyltransferase type 11; KEGG: nml:Namu_0972 ubiquinone/menaquinone biosynthesis methyltransferase. (227 aa)
Desaf_2509KEGG: dma:DMR_28220 isocitrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase. (384 aa)
Desaf_2750PFAM: Metallophosphoesterase; KEGG: dma:DMR_23200 hypothetical protein. (221 aa)
Desaf_2830PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: 4Fe-4S ferredoxin iron-sulfur-binding domain-containing protein. (280 aa)
Desaf_2881PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; FAD dependent oxidoreductase; KEGG: dde:Dde_3526 heterodisulfide reductase subunit A. (659 aa)
Desaf_3077PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: 4Fe-4S ferredoxin iron-sulfur-binding domain-containing protein. (146 aa)
Desaf_3127KEGG: dvl:Dvul_1245 nickel-dependent hydrogenase, large subunit; PFAM: Nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (569 aa)
Desaf_3128TIGRFAM: [Ni-Fe]-hydrogenase, small subunit; Twin-arginine translocation pathway, signal sequence; KEGG: drt:Dret_0265 hydrogenase (NiFe) small subunit HydA; PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; Twin-arginine translocation pathway, signal sequence, subgroup. (317 aa)
Desaf_3130KEGG: dsa:Desal_2049 nickel-dependent hydrogenase large subunit; PFAM: Nickel-dependent hydrogenase, large subunit. (477 aa)
Desaf_3131TIGRFAM: [Ni-Fe]-hydrogenase, small subunit; Twin-arginine translocation pathway, signal sequence; KEGG: dsa:Desal_2050 hydrogenase (NiFe) small subunit HydA; PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit. (307 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (721 aa)
Desaf_3550Nitrate reductase; KEGG: dba:Dbac_0171 molybdopterin oxidoreductase; PFAM: Molydopterin dinucleotide-binding region; Molybdopterin oxidoreductase; Molybdopterin oxidoreductase Fe4S4 region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (711 aa)
Desaf_3633NADH dehydrogenase (quinone); KEGG: NADH/ubiquinone/plastoquinone (complex I); PFAM: NADH:ubiquinone/plastoquinone oxidoreductase. (497 aa)
Desaf_3634NADH dehydrogenase (quinone); KEGG: NADH/ubiquinone/plastoquinone (complex I); PFAM: NADH:ubiquinone/plastoquinone oxidoreductase. (493 aa)
Desaf_3637NADH dehydrogenase (quinone); KEGG: dal:Dalk_4926 putative monovalent cation/H+ antiporter subunit D; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase. (599 aa)
Desaf_3699PFAM: Polysulphide reductase, NrfD; KEGG: dsa:Desal_1045 polysulphide reductase NrfD. (414 aa)
Desaf_3700PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: dba:Dbac_3392 4Fe-4S ferredoxin iron-sulfur binding domain protein. (263 aa)
Desaf_3701PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding region; KEGG: dma:DMR_18020 molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (714 aa)
Your Current Organism:
Desulfocurvibacter africanus
NCBI taxonomy Id: 690850
Other names: D. africanus subsp. africanus str. Walvis Bay, Desulfocurvibacter africanus str. Walvis Bay, Desulfocurvibacter africanus subsp. africanus str. Walvis Bay, Desulfovibrio africanus ATCC 19997, Desulfovibrio africanus str. Walvis Bay, Desulfovibrio africanus strain Walvis Bay
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