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Desaf_0481 Desaf_0481 fcl fcl gmd gmd Desaf_0875 Desaf_0875 Desaf_1013 Desaf_1013 Desaf_1014 Desaf_1014 Desaf_1015 Desaf_1015 Desaf_1024 Desaf_1024 Desaf_1146 Desaf_1146 Desaf_1280 Desaf_1280 Desaf_1351 Desaf_1351 Desaf_1382 Desaf_1382 glmU glmU Desaf_2131 Desaf_2131 Desaf_2132 Desaf_2132 Desaf_2305 Desaf_2305 Desaf_2415 Desaf_2415 Desaf_2725 Desaf_2725 Desaf_3280 Desaf_3280
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Desaf_0481dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (181 aa)
fclGDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (316 aa)
gmdGDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (386 aa)
Desaf_0875KEGG: dba:Dbac_1508 UTP--glucose-1-phosphate uridylyltransferase; PFAM: UTP--glucose-1-phosphate uridylyltransferase. (487 aa)
Desaf_1013TIGRFAM: dTDP-glucose 4,6-dehydratase; KEGG: bph:Bphy_2319 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (358 aa)
Desaf_1014Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (301 aa)
Desaf_1015dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (177 aa)
Desaf_1024TIGRFAM: Nucleotide sugar dehydrogenase; KEGG: cvi:CV_4129 udpglucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase, C-terminal; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (435 aa)
Desaf_1146PFAM: NAD-dependent epimerase/dehydratase; KEGG: tye:THEYE_A0474 CDP-tyvelose epimerase. (358 aa)
Desaf_1280Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (302 aa)
Desaf_1351KEGG: rce:RC1_0527 CDP-paratose 2-epimerase; PFAM: NAD-dependent epimerase/dehydratase. (367 aa)
Desaf_1382TIGRFAM: Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: gem:GM21_2590 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type II, C-terminal; Nucleotidyl transferase. (534 aa)
glmUBifunctional protein glmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (458 aa)
Desaf_2131dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (293 aa)
Desaf_2132TIGRFAM: dTDP-glucose 4,6-dehydratase; KEGG: dvm:DvMF_0141 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (340 aa)
Desaf_2305TIGRFAM: UDP-glucose 4-epimerase; KEGG: cyc:PCC7424_4242 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (326 aa)
Desaf_2415UDP-glucuronate 5'-epimerase; KEGG: dde:Dde_0033 NAD-dependent epimerase/dehydratase family protein; PFAM: NAD-dependent epimerase/dehydratase. (335 aa)
Desaf_2725TIGRFAM: Nucleotide sugar dehydrogenase; KEGG: dba:Dbac_1843 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase, C-terminal. (447 aa)
Desaf_3280UTP--glucose-1-phosphate uridylyltransferase; KEGG: dsa:Desal_1798 nucleotidyl transferase; PFAM: Nucleotidyl transferase. (289 aa)
Your Current Organism:
Desulfocurvibacter africanus
NCBI taxonomy Id: 690850
Other names: D. africanus subsp. africanus str. Walvis Bay, Desulfocurvibacter africanus str. Walvis Bay, Desulfocurvibacter africanus subsp. africanus str. Walvis Bay, Desulfovibrio africanus ATCC 19997, Desulfovibrio africanus str. Walvis Bay, Desulfovibrio africanus strain Walvis Bay
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