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| | Desaf_0028 | PFAM: Aminotransferase, class IV; KEGG: class IV aminotransferase. (313 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (341 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (419 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (307 aa) |
| | Desaf_0088 | 6-phosphogluconate dehydrogenase, decarboxylating; TIGRFAM: 6-phosphogluconate dehydrogenase related protein; KEGG: drt:Dret_2486 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; 6-phosphogluconate dehydrogenase, C-terminal. (302 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (523 aa) |
| | Desaf_0090 | Transketolase; KEGG: tye:THEYE_A0954 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal. (614 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (234 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (468 aa) |
| | Desaf_0114 | Arginase; TIGRFAM: Arginase, subgroup; KEGG: bts:Btus_0192 arginase; PFAM: Ureohydrolase; Belongs to the arginase family. (330 aa) |
| | glgB | 1,4-alpha-glucan-branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (644 aa) |
| | glgA | Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (494 aa) |
| | argD | PFAM: Aminotransferase class-III; TIGRFAM: Acetylornithine/succinylornithine aminotransferase; HAMAP: Acetylornithine/succinyldiaminopimelate aminotransferase; KEGG: dma:DMR_45620 acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (399 aa) |
| | Desaf_0159 | TIGRFAM: Alpha-glucan phosphorylase; KEGG: dma:DMR_45660 putative glycogen phosphorylase; PFAM: Glycosyl transferase, family 35. (857 aa) |
| | Desaf_0176 | Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (238 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (282 aa) |
| | Desaf_0187 | TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: dma:DMR_28790 glyceraldehyde-3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (340 aa) |
| | Desaf_0189 | TIGRFAM: Hopene cyclase; Squalene cyclase; KEGG: gme:Gmet_0419 terpene synthase:squalene cyclase; PFAM: Prenyltransferase/squalene oxidase. (687 aa) |
| | gpmA | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (247 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (164 aa) |
| | purD | Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; TIGRFAM: Phosphoribosylglycinamide synthetase; HAMAP: Phosphoribosylglycinamide synthetase; KEGG: dsa:Desal_3434 phosphoribosylamine/glycine ligase; Belongs to the GARS family. (425 aa) |
| | Desaf_0269 | TIGRFAM: Flavoprotein WrbA; HAMAP: Flavoprotein wrbA; KEGG: sfu:Sfum_3387 TrpR binding protein WrbA; PFAM: Flavodoxin/nitric oxide synthase. (203 aa) |
| | Desaf_0287 | PFAM: 6-phosphogluconate dehydrogenase, NAD-binding protein; KEGG: dae:Dtox_1550 6-phosphogluconate dehydrogenase NAD-binding. (236 aa) |
| | Desaf_0304 | Transketolase; KEGG: tye:THEYE_A0954 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal. (621 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (367 aa) |
| | rpiA | Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (246 aa) |
| | acsA | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (663 aa) |
| | Desaf_0342 | TIGRFAM: Sulphate adenylyltransferase; KEGG: dba:Dbac_3196 sulfate adenylyltransferase; PFAM: Sulphate adenylyltransferase. (426 aa) |
| | Desaf_0345 | KEGG: dma:DMR_39020 aconitate hydratase; TIGRFAM: Aconitase, putative; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel. (641 aa) |
| | argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (397 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (351 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (448 aa) |
| | Desaf_0481 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (181 aa) |
| | Desaf_0487 | KEGG: tra:Trad_0749 phosphoglucomutase, alpha-D-glucose phosphate-specific; TIGRFAM: Phosphoglucomutase, alpha-D-glucose specific; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, C-terminal. (550 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (284 aa) |
| | Desaf_0530 | Trehalose-phosphatase; KEGG: nhl:Nhal_3182 beta-phosphoglucomutase family hydrolase; TIGRFAM: Trehalose-phosphatase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Glycoside hydrolase family 65, central catalytic; Trehalose-phosphatase; Glycoside hydrolase family 65, N-terminal. (1095 aa) |
| | Desaf_0547 | PFAM: Saccharopine dehydrogenase; KEGG: dba:Dbac_2320 saccharopine dehydrogenase. (398 aa) |
| | ilvD | PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; TIGRFAM: Dihydroxy-acid dehydratase; HAMAP: Dihydroxy-acid dehydratase; KEGG: dde:Dde_0116 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (556 aa) |
| | Desaf_0563 | KEGG: dvm:DvMF_0572 threonine aldolase; PFAM: Aromatic amino acid beta-eliminating lyase/threonine aldolase. (341 aa) |
| | ldh | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (328 aa) |
| | Desaf_0614 | KEGG: iron-containing alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, iron-type. (389 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (316 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (177 aa) |
| | Desaf_0721 | KEGG: sfu:Sfum_0630 pyruvate, water dikinase; PFAM: Pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region. (858 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (150 aa) |
| | Desaf_0812 | TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: dma:DMR_28790 glyceraldehyde-3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (338 aa) |
| | Desaf_0832 | Putative cache sensor protein; PFAM: Pyruvate carboxyltransferase; Cache; KEGG: dvl:Dvul_2536 pyruvate carboxyltransferase. (608 aa) |
| | Desaf_0850 | 6-phosphofructokinase; KEGG: dde:Dde_1589 diphosphate--fructose-6-phosphate 1-phosphotransferase; PFAM: Phosphofructokinase. (448 aa) |
| | Desaf_0860 | PFAM: SNARE associated Golgi protein; Phospholipase D/Transphosphatidylase; KEGG: nhl:Nhal_1635 phospholipase D. (731 aa) |
| | Desaf_0875 | KEGG: dba:Dbac_1508 UTP--glucose-1-phosphate uridylyltransferase; PFAM: UTP--glucose-1-phosphate uridylyltransferase. (487 aa) |
| | Desaf_0913 | KEGG: dsa:Desal_3779 HAD-superfamily hydrolase, subfamily IA, variant 1; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase-like hydrolase. (234 aa) |
| | Desaf_0926 | 4-alpha-glucanotransferase; TIGRFAM: Glycoside hydrolase, family 77; KEGG: sfu:Sfum_3452 4-alpha-glucanotransferase; PFAM: Glycoside hydrolase, family 77. (499 aa) |
| | Desaf_0970 | PFAM: Methyltransferase type 11; KEGG: dvl:Dvul_1711 methyltransferase type 11. (216 aa) |
| | Desaf_0973 | Aspartate transaminase; KEGG: dvm:DvMF_2204 aminotransferase class I and II; PFAM: Aminotransferase, class I/II. (391 aa) |
| | Desaf_0980 | TIGRFAM: Anaerobic glycerol-3-phosphate dehydrogenase, subunit B; KEGG: dvu:DVU1939 anaerobic glycerol-3-phosphate dehydrogenase subunit B; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal. (441 aa) |
| | Desaf_0981 | Glycerol-3-phosphate dehydrogenase; KEGG: dba:Dbac_1438 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase. (532 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (226 aa) |
| | Desaf_1011 | TIGRFAM: Uroporphyrin-III C-methyltransferase, C-terminal; KEGG: dsa:Desal_0251 uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole methylase; Tetrapyrrole biosynthesis, uroporphyrinogen III synthase. (507 aa) |
| | Desaf_1013 | TIGRFAM: dTDP-glucose 4,6-dehydratase; KEGG: bph:Bphy_2319 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (358 aa) |
| | Desaf_1014 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (301 aa) |
| | Desaf_1015 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (177 aa) |
| | Desaf_1033 | PFAM: Methyltransferase type 12; KEGG: msl:Msil_2729 methyltransferase type 11. (313 aa) |
| | panC | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (285 aa) |
| | Desaf_1085 | PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: dsa:Desal_3826 4Fe-4S ferredoxin iron-sulfur binding domain protein. (82 aa) |
| | Desaf_1086 | 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin); KEGG: dsa:Desal_3825 2-ketoisovalerate ferredoxin reductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal. (358 aa) |
| | Desaf_1087 | 2-oxoglutarate synthase; KEGG: drt:Dret_0090 thiamine pyrophosphate protein domain protein TPP-binding; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding protein. (255 aa) |
| | Desaf_1088 | PFAM: Pyruvate/ketoisovalerate oxidoreductase; KEGG: dvl:Dvul_0047 pyruvate ferredoxin/flavodoxin oxidoreductase. (180 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (351 aa) |
| | Desaf_1096 | KEGG: dsa:Desal_3030 STE24 endopeptidase; PFAM: Peptidase M48, Ste24p. (419 aa) |
| | pgi | HAMAP: Phosphoglucose isomerase (PGI); KEGG: tgr:Tgr7_0871 glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase (PGI); Belongs to the GPI family. (547 aa) |
| | Desaf_1132 | Anthranilate synthase; KEGG: glutamine amidotransferase; PFAM: Glutamine amidotransferase class-I, C-terminal. (182 aa) |
| | metK | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (493 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (297 aa) |
| | hisI | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (123 aa) |
| | Desaf_1160 | 6-phosphofructokinase; KEGG: dba:Dbac_0531 diphosphate--fructose-6-phosphate 1-phosphotransferase; PFAM: Phosphofructokinase. (443 aa) |
| | aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (305 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (282 aa) |
| | gluQ | Glutamyl-Q tRNA(Asp) synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (323 aa) |
| | Desaf_1251 | Butyrate--CoA ligase; KEGG: dma:DMR_19670 putative acetyl-coenzyme A synthetase; PFAM: AMP-dependent synthetase/ligase. (549 aa) |
| | Desaf_1258 | PFAM: Phosphopantetheine-binding protein; KEGG: dak:DaAHT2_1140 acyl carrier protein. (87 aa) |
| | gpt | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (164 aa) |
| | Desaf_1265 | PFAM: Aldehyde dehydrogenase; KEGG: ava:Ava_3615 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (466 aa) |
| | Desaf_1273 | KEGG: dma:DMR_17130 serine acetyltransferase; PFAM: Bacterial transferase hexapeptide repeat. (301 aa) |
| | Desaf_1274 | TIGRFAM: Cysteine synthase K/M; Cysteine synthase A; KEGG: dma:DMR_17120 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. (311 aa) |
| | Desaf_1280 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (302 aa) |
| | Desaf_1283 | PFAM: Carboxylyase-related; KEGG: UbiD family decarboxylase; Belongs to the UbiD family. (618 aa) |
| | Desaf_1288 | TIGRFAM: Glycerate kinase; KEGG: bts:Btus_3261 glycerate kinase; PFAM: Glycerate kinase; Belongs to the glycerate kinase type-1 family. (388 aa) |
| | Desaf_1308 | TIGRFAM: Riboflavin kinase/FAD synthetase; KEGG: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; Belongs to the ribF family. (315 aa) |
| | aroK-2 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (207 aa) |
| | Desaf_1350 | KEGG: rce:RC1_0526 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase. (371 aa) |
| | Desaf_1352 | KEGG: rce:RC1_0528 oxidoreductase with radical SAM domain, putative; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB. (424 aa) |
| | Desaf_1363 | PFAM: Myo-inositol-1-phosphate synthase; Myo-inositol-1-phosphate synthase, GAPDH-like; KEGG: mem:Memar_0974 myo-inositol-1-phosphate synthase. (367 aa) |
| | Desaf_1382 | TIGRFAM: Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: gem:GM21_2590 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type II, C-terminal; Nucleotidyl transferase. (534 aa) |
| | Desaf_1391 | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (639 aa) |
| | Desaf_1392 | TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; KEGG: tgr:Tgr7_2387 asparagine synthase (glutamine-hydrolyzing); PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. (655 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (259 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (213 aa) |
| | Desaf_1496 | PFAM: 6-phosphogluconate dehydrogenase, NAD-binding protein; KEGG: tro:trd_1142 6-phosphogluconate dehydrogenase-like protein. (238 aa) |
| | trpF | KEGG: drt:Dret_0255 N-(5'phosphoribosyl)anthranilate isomerase (PRAI); PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); Belongs to the TrpF family. (246 aa) |
| | Desaf_1509 | KEGG: glucokinase; PFAM: Glucokinase; Belongs to the bacterial glucokinase family. (316 aa) |
| | Desaf_1525 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. (1003 aa) |
| | Desaf_1530 | TIGRFAM: Phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB, PSPase-like; KEGG: dma:DMR_33050 phosphoserine phosphatase; PFAM: Haloacid dehalogenase-like hydrolase; Amino acid-binding ACT. (404 aa) |
| | Desaf_1541 | TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; KEGG: pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase. (564 aa) |
| | Desaf_1542 | TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate; KEGG: dde:Dde_1793 2-oxoacid:acceptor oxidoreductase subunit beta, pyruvate/2-ketoisovalerate; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding protein. (295 aa) |
| | Desaf_1596 | KEGG: dba:Dbac_3374 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase related; PFAM: UbiA prenyltransferase; Belongs to the UbiA prenyltransferase family. (295 aa) |
| | Desaf_1603 | D-lactate dehydrogenase (cytochrome); KEGG: dvu:DVU0827 glycolate oxidase, subunit GlcD, putative; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal. (456 aa) |
| | Desaf_1604 | PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Cysteine-rich region, CCG; KEGG: dma:DMR_07460 iron-sulfur binding protein. (397 aa) |
| | Desaf_1650 | Glyoxylate reductase; KEGG: geo:Geob_1052 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region. (320 aa) |
| | Desaf_1686 | PFAM: Fumarate reductase respiratory complex; KEGG: dsa:Desal_0720 fumarate reductase respiratory complex transmembrane subunit. (220 aa) |
| | Desaf_1687 | TIGRFAM: Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; KEGG: dba:Dbac_3065 fumarate reductase flavoprotein subunit; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal. (631 aa) |
| | Desaf_1688 | KEGG: dsa:Desal_0722 fumarate reductase iron-sulfur subunit; TIGRFAM: Succinate dehydrogenase/fumarate reductase iron-sulphur protein. (244 aa) |
| | Desaf_1689 | Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; TIGRFAM: Fe-S type hydro-lyases tartrate/fumarate alpha region; KEGG: dba:Dbac_3063 fumarate hydratase; PFAM: Fe-S type hydro-lyases tartrate/fumarate alpha region. (279 aa) |
| | Desaf_1690 | TIGRFAM: Fe-S type hydro-lyases tartrate/fumarate beta region; KEGG: dba:Dbac_3062 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyases tartrate/fumarate beta region. (185 aa) |
| | glcB | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (723 aa) |
| | mqnA | Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (286 aa) |
| | mqnC | Menaquinone biosynthesis protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (369 aa) |
| | mqnE | Putative menaquinone biosynthesis protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (384 aa) |
| | mqnD | Hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (279 aa) |
| | Desaf_1752 | Aspartate transaminase; KEGG: class I/II aminotransferase; PFAM: Aminotransferase, class I/II. (394 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (995 aa) |
| | Desaf_1764 | KEGG: dvl:Dvul_0208 trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (334 aa) |
| | mqnB | Futalosine nucleosidase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). (244 aa) |
| | ubiE | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (251 aa) |
| | hemL | Glutamate-1-semialdehyde 2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; HAMAP: Glutamate-1-semialdehyde 2,1-aminomutase; KEGG: dba:Dbac_3003 glutamate-1-semialdehyde-2,1-aminomutase. (423 aa) |
| | gpsA | KEGG: dma:DMR_11830 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; HAMAP: Glycerol-3-phosphate dehydrogenase [NAD(P)+]; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase, C-terminal; NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (331 aa) |
| | Desaf_1805 | TIGRFAM: Glutamate synthase (NADPH), homotetrameric; KEGG: dvl:Dvul_0766 putative oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (482 aa) |
| | plsY | Glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (201 aa) |
| | Desaf_1854 | PFAM: AICARFT/IMPCHase bienzyme, formylation region; KEGG: phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme, formylation region. (424 aa) |
| | trpA | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (258 aa) |
| | trpB | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (393 aa) |
| | trpF-2 | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: dma:DMR_05270 N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (207 aa) |
| | Desaf_1873 | KEGG: dma:DMR_05280 indole-3-glycerol phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (263 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (336 aa) |
| | Desaf_1875 | TIGRFAM: Glutamine amidotransferase of anthranilate synthase; KEGG: glutamine amidotransferase of anthranilate synthase; PFAM: Glutamine amidotransferase class-I, C-terminal. (193 aa) |
| | Desaf_1876 | KEGG: dma:DMR_05320 anthranilate synthase component I; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal. (471 aa) |
| | Desaf_1877 | PFAM: Prephenate dehydrogenase; KEGG: dba:Dbac_2811 prephenate dehydrogenase. (258 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (443 aa) |
| | Desaf_1879 | Chorismate mutase; KEGG: dvm:DvMF_1749 prephenate dehydratase; TIGRFAM: Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain; PFAM: Prephenate dehydratase; Chorismate mutase, type II; Amino acid-binding ACT. (429 aa) |
| | Desaf_1880 | PFAM: 3-dehydroquinate synthase, prokaryotic-type; KEGG: dvm:DvMF_1750 3-dehydroquinate synthase. (327 aa) |
| | aroA-2 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (275 aa) |
| | hisC | PFAM: Aminotransferase, class I/II; TIGRFAM: Histidinol-phosphate aminotransferase; HAMAP: Histidinol-phosphate aminotransferase; KEGG: dba:Dbac_0507 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (370 aa) |
| | Desaf_1982 | NAD(P)H dehydrogenase (quinone); PFAM: Flavodoxin-like fold; KEGG: dbr:Deba_0532 NAD(P)H dehydrogenase (quinone). (198 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (340 aa) |
| | hisC-2 | PFAM: Aminotransferase, class I/II; TIGRFAM: Histidinol-phosphate aminotransferase; HAMAP: Histidinol-phosphate aminotransferase; KEGG: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (370 aa) |
| | Desaf_2091 | Fructose-1,6-bisphosphatase, class II; TIGRFAM: GlpX; KEGG: fructose-1,6-bisphosphatase; PFAM: GlpX. (327 aa) |
| | Desaf_2092 | Sugar-phosphate isomerase, RpiB/LacA/LacB family; TIGRFAM: Ribose/galactose isomerase; Ribose 5-phosphate isomerase B; KEGG: dma:DMR_21090 ribose-5-phosphate isomerase B; PFAM: Ribose/galactose isomerase. (152 aa) |
| | Desaf_2098 | Methionine synthase; KEGG: homocysteine S-methyltransferase; PFAM: Homocysteine S-methyltransferase; Dihydropteroate synthase, DHPS; Methionine synthase, cobalamin (vitamin B12)-binding module, cap; Cobalamin (vitamin B12)-binding protein. (802 aa) |
| | Desaf_2100 | PFAM: GCN5-related N-acetyltransferase; KEGG: dba:Dbac_1857 acetyltransferase. (158 aa) |
| | Desaf_2101 | TIGRFAM: Hypoxanthine phosphoribosyl transferase; KEGG: dba:Dbac_1856 hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (181 aa) |
| | Desaf_2131 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (293 aa) |
| | Desaf_2132 | TIGRFAM: dTDP-glucose 4,6-dehydratase; KEGG: dvm:DvMF_0141 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (340 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (266 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa) |
| | Desaf_2182 | Protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: Cysteine-rich region, CCG; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: hypothetical protein. (428 aa) |
| | Desaf_2183 | D-lactate dehydrogenase (cytochrome); KEGG: FAD linked oxidase domain-containing protein; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal. (462 aa) |
| | Desaf_2186 | TIGRFAM: Pyruvate-flavodoxin oxidoreductase; KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding protein. (1232 aa) |
| | Desaf_2266 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (274 aa) |
| | Desaf_2270 | KEGG: dvm:DvMF_0817 biotin carboxylase; PFAM: Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, ATP-binding; Biotin carboxylase, C-terminal. (471 aa) |
| | Desaf_2271 | KEGG: drt:Dret_1121 acetyl-CoA carboxylase; PFAM: Acetyl-CoA carboxylase, alpha subunit, conserved region. (750 aa) |
| | Desaf_2280 | Pyruvate, water dikinase; KEGG: pyruvate phosphate dikinase pEp/pyruvate-binding protein; PFAM: Pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region. (865 aa) |
| | Desaf_2308 | TIGRFAM: Phosphoribosyl pyrophosphokinase; KEGG: aeh:Mlg_1731 ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyltransferase. (325 aa) |
| | ribH | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (156 aa) |
| | ribBA | GTP cyclohydrolase-2; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (413 aa) |
| | Desaf_2343 | Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; KEGG: dba:Dbac_0061 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. (220 aa) |
| | Desaf_2344 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (380 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (412 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (76 aa) |
| | Desaf_2349 | 3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (247 aa) |
| | plsX | Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (350 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (462 aa) |
| | Desaf_2373 | Putative transcriptional regulator, GntR family; KEGG: dma:DMR_38090 aminotransferase; PFAM: Aminotransferase, class I/II. (394 aa) |
| | surE | Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (252 aa) |
| | Desaf_2391 | TIGRFAM: Fructose-1,6-bisphosphate aldolase, class II; Ketose-bisphosphate aldolase, class-II; KEGG: dvl:Dvul_1089 fructose-1,6-bisphosphate aldolase, class II; PFAM: Ketose-bisphosphate aldolase, class-II. (309 aa) |
| | Desaf_2392 | TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: dba:Dbac_0093 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (330 aa) |
| | Desaf_2414 | PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, C-terminal; KEGG: dma:DMR_27100 phosphohexose mutase. (464 aa) |
| | Desaf_2420 | KEGG: dvm:DvMF_1468 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (435 aa) |
| | Desaf_2454 | KEGG: dvl:Dvul_1521 putative glutamate synthase subunit beta; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (380 aa) |
| | Desaf_2455 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (668 aa) |
| | ispDF | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). (410 aa) |
| | Desaf_2499 | PFAM: Methyltransferase type 11; KEGG: nml:Namu_0972 ubiquinone/menaquinone biosynthesis methyltransferase. (227 aa) |
| | Desaf_2509 | KEGG: dma:DMR_28220 isocitrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase. (384 aa) |
| | Desaf_2530 | PFAM: 6-phosphogluconate dehydrogenase, NAD-binding protein; KEGG: tra:Trad_1969 6-phosphogluconate dehydrogenase. (233 aa) |
| | aroA-3 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (265 aa) |
| | Desaf_2640 | TIGRFAM: Ribulose-phosphate 3-epimerase; KEGG: dsa:Desal_1238 ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (240 aa) |
| | Desaf_2642 | KEGG: dsa:Desal_1240 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB. (406 aa) |
| | Desaf_2643 | KEGG: dsa:Desal_1241 porphobilinogen synthase; PFAM: Tetrapyrrole biosynthesis, porphobilinogen synthase; Belongs to the ALAD family. (323 aa) |
| | Desaf_2646 | KEGG: dvl:Dvul_2126 radical SAM domain-containing protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB. (413 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (423 aa) |
| | Desaf_2659 | PFAM: Phosphatidate cytidylyltransferase; KEGG: drt:Dret_1946 phosphatidate cytidylyltransferase; Belongs to the CDS family. (267 aa) |
| | Desaf_2664 | PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; KEGG: dsa:Desal_2440 homoserine dehydrogenase. (429 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (307 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (316 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (291 aa) |
| | Desaf_2718 | TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase related; KEGG: dsa:Desal_1998 putative alpha-isopropylmalate/homocitrate synthase family transferase; PFAM: 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; Pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (542 aa) |
| | Desaf_2719 | KEGG: dma:DMR_17890 aspartate kinase; TIGRFAM: Aspartate kinase region; Aspartate kinase, monofunctional class; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Belongs to the aspartokinase family. (410 aa) |
| | Desaf_2740 | (Acyl-carrier-protein) S-malonyltransferase; KEGG: dba:Dbac_1606 acyl transferase; PFAM: Acyl transferase. (310 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (223 aa) |
| | Desaf_2797 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (325 aa) |
| | argG | PFAM: Argininosuccinate synthase; TIGRFAM: Argininosuccinate synthase; HAMAP: Argininosuccinate synthase; KEGG: drt:Dret_1729 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (398 aa) |
| | argH | PFAM: Fumarate lyase; TIGRFAM: Argininosuccinate lyase; HAMAP: Argininosuccinate lyase; KEGG: argininosuccinate lyase. (464 aa) |
| | Desaf_2806 | TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: Phospholipid/glycerol acyltransferase; KEGG: dma:DMR_37970 acyltransferase; SMART: Phospholipid/glycerol acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (239 aa) |
| | Desaf_2828 | TIGRFAM: Homoserine kinase, putative; Cofactor-independent phosphoglycerate mutase, archaeal; KEGG: proposed homoserine kinase; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Metalloenzyme. (399 aa) |
| | aroA-4 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (267 aa) |
| | Desaf_2884 | Alcohol dehydrogenase; KEGG: dba:Dbac_3326 iron-containing alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, iron-type. (393 aa) |
| | Desaf_2887 | Alcohol dehydrogenase; KEGG: dvm:DvMF_0330 iron-containing alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, iron-type. (380 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (261 aa) |
| | dapB-2 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (261 aa) |
| | Desaf_2946 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (800 aa) |
| | Desaf_2951 | TIGRFAM: Siroheme synthase, N-terminal; KEGG: siroheme synthase. (239 aa) |
| | hemA | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (450 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (364 aa) |
| | Desaf_2969 | Farnesyltranstransferase; KEGG: dvl:Dvul_1719 polyprenyl synthetase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (298 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (666 aa) |
| | Desaf_2972 | TIGRFAM: Adenylylsulphate kinase, C-terminal; KEGG: drt:Dret_2034 bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; PFAM: Sulphate adenylyltransferase; Adenylylsulphate kinase, C-terminal. (570 aa) |
| | Desaf_2973 | Malto-oligosyltrehalose trehalohydrolase; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region; TIGRFAM: Malto-oligosyltrehalose trehalohydrolase; KEGG: sfu:Sfum_2349 malto-oligosyltrehalose trehalohydrolase; PFAM: Glycosyl hydrolase, family 13, catalytic region; Glycoside hydrolase, family 13, N-terminal. (650 aa) |
| | glgB-2 | 1,4-alpha-glucan-branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (664 aa) |
| | Desaf_2975 | Trehalose synthase; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region; TIGRFAM: Trehalose synthase/alpha-amylase, N-terminal; Trehalose synthase/probable maltokinase, C-terminal; KEGG: cag:Cagg_2090 trehalose synthase; PFAM: Glycosyl hydrolase, family 13, catalytic region; Aminoglycoside phosphotransferase. (1102 aa) |
| | miaA | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (311 aa) |
| | Desaf_3002 | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: dsa:Desal_2398 acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, central region; Thiamine pyrophosphate enzyme, C-terminal TPP-binding protein. (565 aa) |
| | Desaf_3003 | KEGG: dma:DMR_21840 acetolactate synthase 3 regulatory subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. (159 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (329 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (156 aa) |
| | ubiX | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (192 aa) |
| | dapL | LL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. (388 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (420 aa) |
| | Desaf_3067 | KEGG: dba:Dbac_1640 glutamate synthase (ferredoxin); PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal. (1532 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa) |
| | pgk | HAMAP: Phosphoglycerate kinase; KEGG: dba:Dbac_0879 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (397 aa) |
| | Desaf_3087 | PFAM: NUDIX hydrolase domain; KEGG: dma:DMR_18290 isopentenyl-diphosphate delta-isomerase family protein. (187 aa) |
| | Desaf_3088 | PFAM: Inositol monophosphatase; KEGG: inositol monophosphatase. (262 aa) |
| | Desaf_3092 | TIGRFAM: Glycine cleavage system T protein; KEGG: dde:Dde_1996 glycine cleavage system T protein; PFAM: Glycine cleavage T-protein, N-terminal; Glycine cleavage T-protein, C-terminal barrel. (361 aa) |
| | Desaf_3108 | KEGG: alpha,alpha-trehalose-phosphate synthase; PFAM: Glycosyl transferase, family 20. (489 aa) |
| | fbp | HAMAP: Fructose-1,6-bisphosphatase; KEGG: dvm:DvMF_0404 fructose-1,6-bisphosphatase; PFAM: Fructose-1,6-bisphosphatase; Belongs to the FBPase class 1 family. (340 aa) |
| | Desaf_3133 | Pyruvate, water dikinase., Phosphoenolpyruvate--protein phosphotransferase; KEGG: dvm:DvMF_0416 pyruvate phosphate dikinase PEP/pyruvate-binding; PFAM: Pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region; PEP-utilising enzyme. (1198 aa) |
| | Desaf_3137 | S-adenosylhomocysteine deaminase; KEGG: dvu:DVU2900 amidohydrolase family protein; PFAM: Amidohydrolase 1. (385 aa) |
| | Desaf_3175 | KEGG: phosphoribosylformylglycinamidine synthase. (269 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (439 aa) |
| | purC | PFAM: SAICAR synthetase; TIGRFAM: SAICAR synthetase; HAMAP: Phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: dma:DMR_22050 phosphoribosylaminoimidazole-succinocarboxamide synthase. (298 aa) |
| | Desaf_3205 | Enoyl-(acyl-carrier-protein) reductase, NADH; KEGG: dvl:Dvul_2180 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR. (254 aa) |
| | Desaf_3212 | KEGG: threonine synthase; TIGRFAM: Threonine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit. (483 aa) |
| | Desaf_3217 | PFAM: Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: pmr:PMI1592 fructose-bisphosphate aldolase. (349 aa) |
| | hisA | PFAM: Histidine biosynthesis; TIGRFAM: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; HAMAP: 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; KEGG: dsa:Desal_1557 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (242 aa) |
| | hisB | HAMAP: Imidazoleglycerol-phosphate dehydratase; KEGG: imidazoleglycerol-phosphate dehydratase; PFAM: Imidazoleglycerol-phosphate dehydratase. (197 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (485 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (361 aa) |
| | leuD | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (167 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (419 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (512 aa) |
| | Desaf_3264 | KEGG: dsa:Desal_1581 CDP-diacylglycerol/serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (255 aa) |
| | psd | Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (214 aa) |
| | Desaf_3280 | UTP--glucose-1-phosphate uridylyltransferase; KEGG: dsa:Desal_1798 nucleotidyl transferase; PFAM: Nucleotidyl transferase. (289 aa) |
| | gpmI | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (525 aa) |
| | Desaf_3325 | PFAM: Amino acid-binding ACT; KEGG: spe:Spro_0733 acetolactate synthase 1 regulatory subunit. (127 aa) |
| | Desaf_3326 | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: dvl:Dvul_2624 acetolactate synthase catalytic subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, central region; Thiamine pyrophosphate enzyme, C-terminal TPP-binding protein. (571 aa) |
| | Desaf_3337 | KEGG: sfu:Sfum_0649 pyruvate, water dikinase; PFAM: Pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region. (869 aa) |
| | Desaf_3371 | PFAM: Asparaginase/glutaminase; KEGG: drt:Dret_0438 asparaginase/glutaminase. (169 aa) |
| | sucD | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (721 aa) |
| | Desaf_3379 | L-serine dehydratase 1; TIGRFAM: Iron-sulphur-dependent L-serine dehydratase single chain form; KEGG: dvm:DvMF_0011 serine dehydratase alpha chain; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. (454 aa) |
| | Desaf_3393 | Malto-oligosyltrehalose trehalohydrolase; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region; TIGRFAM: Malto-oligosyltrehalose trehalohydrolase; KEGG: cyb:CYB_2529 malto-oligosyltrehalose trehalohydrolase; PFAM: Glycosyl hydrolase, family 13, catalytic region; Glycoside hydrolase, family 13, N-terminal. (619 aa) |
| | Desaf_3395 | TIGRFAM: Malto-oligosyltrehalose synthase; PFAM: Glycosyl hydrolase, family 13, catalytic region; KEGG: npu:Npun_F5706 malto-oligosyltrehalose synthase; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region. (931 aa) |
| | ribB | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (222 aa) |
| | Desaf_3425 | PFAM: GCN5-related N-acetyltransferase; KEGG: pjd:Pjdr2_2169 GCN5-related N-acetyltransferase. (250 aa) |
| | purM | TIGRFAM: Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: dsa:Desal_3132 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase related protein, C-terminal; AIR synthase related protein. (353 aa) |
| | katG | Catalase-peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (737 aa) |
| | eno-2 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) |
| | Desaf_3657 | D-lactate dehydrogenase (cytochrome); KEGG: dvu:DVU0390 glycolate oxidase, subunit GlcD, putative; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal. (462 aa) |
| | Desaf_3662 | KEGG: short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR. (242 aa) |
| | acpP-2 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (85 aa) |
| | Desaf_3667 | KEGG: phospholipid/glycerol acyltransferase; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase. (264 aa) |
| | Desaf_3680 | Radical SAM domain protein; KEGG: cobalamin B12-binding domain-containing protein; PFAM: Radical SAM; Cobalamin (vitamin B12)-binding protein; SMART: Elongator protein 3/MiaB/NifB. (490 aa) |
| | Desaf_3683 | PFAM: Phosphopantetheine-binding protein; KEGG: phosphopantetheine-binding protein. (84 aa) |
| | Desaf_3687 | TIGRFAM: Pyruvate kinase; KEGG: dba:Dbac_3014 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; Belongs to the pyruvate kinase family. (473 aa) |
| | Desaf_3712 | TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; KEGG: dba:Dbac_0125 asparagine synthase (glutamine-hydrolyzing); PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. (574 aa) |
| | Desaf_3714 | 2-oxoglutarate synthase; KEGG: dsa:Desal_1529 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: Pyruvate/ketoisovalerate oxidoreductase. (209 aa) |
| | Desaf_3715 | KEGG: dma:DMR_18780 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding protein. (279 aa) |
| | Desaf_3716 | 2-oxoglutarate synthase; KEGG: pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal. (383 aa) |
| | Desaf_3717 | PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: dvm:DvMF_0602 4Fe-4S ferredoxin iron-sulfur binding domain protein. (108 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (124 aa) |
| | gcvPA | Glycine dehydrogenase (decarboxylating) subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (443 aa) |
| | Desaf_3763 | KEGG: dsa:Desal_2996 glycine dehydrogenase subunit 2. (483 aa) |
| | Desaf_3764 | Dihydrolipoyl dehydrogenase; KEGG: FAD-dependent pyridine nucleotide-disulfide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation. (452 aa) |
