(29 nodes) TP53 Regulates Metabolic Genes network (Fonticula alba)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

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co-expression

protein homology

Your Input:
	H696_09004	Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (541 aa)
	H696_05900	SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family. (117 aa)
	H696_03848	WD_REPEATS_REGION domain-containing protein. (1932 aa)
	H696_01443	Uncharacterized protein. (369 aa)
	H696_00453	Uncharacterized protein. (512 aa)
	H696_00218	DUF862 domain-containing protein. (324 aa)
	H696_01467	Uncharacterized protein. (472 aa)
	H696_00684	Uncharacterized protein. (606 aa)
	H696_00369	Uncharacterized protein. (808 aa)
	H696_09003	Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (240 aa)
	H696_01795	Uncharacterized protein. (471 aa)
	H696_01710	Rap-GAP domain-containing protein. (2656 aa)
	H696_01181	Uncharacterized protein. (302 aa)
	H696_01530	Glucose-6-phosphate isomerase; Belongs to the GPI family. (612 aa)
	H696_02281	WD_REPEATS_REGION domain-containing protein. (367 aa)
	H696_02212	Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (107 aa)
	H696_01859	Cytochrome c oxidase subunit IV. (151 aa)
	H696_03442	DNA damage checkpoint protein rad24; Belongs to the 14-3-3 family. (255 aa)
	H696_02971	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2771 aa)
	H696_02895	Uncharacterized protein. (493 aa)
	H696_04829	Cytochrome c oxidase subunit; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. (81 aa)
	H696_03483	Uncharacterized protein. (345 aa)
	H696_05520	Ras like enriched. (206 aa)
	H696_05253	Aa_trans domain-containing protein. (804 aa)
	H696_04754	Uncharacterized protein. (253 aa)
	H696_04858	Uncharacterized protein. (296 aa)
	H696_04546	Thioredoxin; Belongs to the thioredoxin family. (105 aa)
	H696_09005	Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex. (268 aa)
	H696_05974	Uncharacterized protein. (426 aa)

Your Current Organism:

Fonticula alba

NCBI taxonomy Id: 691883
Other names: F. alba

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H696_00369	H696_01530	A0A058ZEF8	A0A058ZCL6	Uncharacterized protein.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.425
H696_00369	H696_01710	A0A058ZEF8	A0A058ZD52	Uncharacterized protein.	Rap-GAP domain-containing protein.	0.789
H696_00369	H696_02895	A0A058ZEF8	A0A058Z8D4	Uncharacterized protein.	Uncharacterized protein.	0.619
H696_00369	H696_02971	A0A058ZEF8	A0A058Z8J3	Uncharacterized protein.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.813
H696_00369	H696_03483	A0A058ZEF8	A0A058Z7F4	Uncharacterized protein.	Uncharacterized protein.	0.630
H696_00369	H696_03848	A0A058ZEF8	A0A058Z7C1	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.793
H696_00369	H696_05253	A0A058ZEF8	A0A058Z2H0	Uncharacterized protein.	Aa_trans domain-containing protein.	0.611
H696_00369	H696_05520	A0A058ZEF8	A0A058Z1D4	Uncharacterized protein.	Ras like enriched.	0.746
H696_00369	H696_05974	A0A058ZEF8	A0A058Z0C7	Uncharacterized protein.	Uncharacterized protein.	0.598
H696_00453	H696_05974	A0A058ZHC5	A0A058Z0C7	Uncharacterized protein.	Uncharacterized protein.	0.435
H696_00684	H696_05974	A0A058ZGP2	A0A058Z0C7	Uncharacterized protein.	Uncharacterized protein.	0.435
H696_01181	H696_01443	A0A058ZCV5	A0A058ZEY8	Uncharacterized protein.	Uncharacterized protein.	0.585
H696_01181	H696_02212	A0A058ZCV5	A0A058ZAD9	Uncharacterized protein.	Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.496
H696_01181	H696_05974	A0A058ZCV5	A0A058Z0C7	Uncharacterized protein.	Uncharacterized protein.	0.834
H696_01181	H696_09003	A0A058ZCV5	A0A058YZ79	Uncharacterized protein.	Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.	0.535
H696_01443	H696_01181	A0A058ZEY8	A0A058ZCV5	Uncharacterized protein.	Uncharacterized protein.	0.585
H696_01443	H696_01795	A0A058ZEY8	A0A058ZDB2	Uncharacterized protein.	Uncharacterized protein.	0.438
H696_01443	H696_02212	A0A058ZEY8	A0A058ZAD9	Uncharacterized protein.	Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.817
H696_01443	H696_04546	A0A058ZEY8	A0A058Z4S5	Uncharacterized protein.	Thioredoxin; Belongs to the thioredoxin family.	0.585
H696_01443	H696_04754	A0A058ZEY8	A0A058Z2K7	Uncharacterized protein.	Uncharacterized protein.	0.861