(36 nodes) Protein localization to endoplasmic reticulum network (Sphaerulina musiva)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	M3B7Y7_SPHMS	Uncharacterized protein. (587 aa)
	M3C5S5_SPHMS	Translocation protein. (444 aa)
	M3C6Y7_SPHMS	ER lumen protein-retaining receptor. (215 aa)
	N1QL28_SPHMS	Transmembrane emp24 domain-containing protein 2. (202 aa)
	N1QKS6_SPHMS	Hsp70 chaperone BiP/Kar2; Belongs to the heat shock protein 70 family. (684 aa)
	N1QKQ6_SPHMS	Uncharacterized protein. (223 aa)
	N1QKI0_SPHMS	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (519 aa)
	N1QJI7_SPHMS	DUF410-domain-containing protein. (337 aa)
	N1QIN1_SPHMS	TPR_REGION domain-containing protein. (353 aa)
	N1QIL7_SPHMS	Uncharacterized protein. (205 aa)
	M3CJM4_SPHMS	B-cell receptor-associated 31-like protein. (207 aa)
	N1QI83_SPHMS	P-loop containing nucleoside triphosphate hydrolase protein. (297 aa)
	N1QGZ0_SPHMS	WSC domain-containing protein. (443 aa)
	N1QGM9_SPHMS	Protein transport protein SEC61 subunit alpha. (476 aa)
	N1QGM6_SPHMS	Signal peptidase subunit 3. (255 aa)
	N1QFG2_SPHMS	SPC12-domain-containing protein. (107 aa)
	N1QFD4_SPHMS	Inorganic phosphate transport PHO88. (178 aa)
	N1QE23_SPHMS	Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family. (650 aa)
	M3DAF1_SPHMS	J domain-containing protein. (707 aa)
	GET3	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (334 aa)
	M3D8V4_SPHMS	ER_lumen_recept-domain-containing protein. (374 aa)
	M3D5V5_SPHMS	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (111 aa)
	M3D3L9_SPHMS	Signal recognition particle, SRP9/SRP14 subunit. (138 aa)
	M3D215_SPHMS	Signal peptidase complex catalytic subunit SEC11. (174 aa)
	M3D1D5_SPHMS	Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment. (189 aa)
	N1QLK5_SPHMS	DUF747-domain-containing protein. (865 aa)
	M3CP32_SPHMS	SRP9-21 domain-containing protein. (167 aa)
	M3CXB7_SPHMS	ICE2-domain-containing protein. (438 aa)
	N1QM93_SPHMS	P-loop containing nucleoside triphosphate hydrolase protein. (696 aa)
	M3C0F6_SPHMS	Uncharacterized protein. (274 aa)
	M3B7S0_SPHMS	Uncharacterized protein. (181 aa)
	M3B5P4_SPHMS	Signal recognition particle, SRP19 subunit. (206 aa)
	M3B5B9_SPHMS	Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family. (634 aa)
	M3AUU9_SPHMS	EXS-domain-containing protein. (369 aa)
	M3AT02_SPHMS	L domain-like protein. (246 aa)
	M3ARB9_SPHMS	Protein translocase SEC6. (69 aa)

Your Current Organism:

Sphaerulina musiva

NCBI taxonomy Id: 692275
Other names: Mycosphaerella populorum SO2202, S. musiva SO2202, Septoria musiva SO2202, Sphaerulina musiva SO2202

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GET3	M3ARB9_SPHMS	M3D935	M3ARB9	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	Protein translocase SEC6.	0.457
GET3	M3D5V5_SPHMS	M3D935	M3D5V5	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.845
GET3	N1QGM9_SPHMS	M3D935	N1QGM9	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	Protein transport protein SEC61 subunit alpha.	0.670
GET3	N1QIN1_SPHMS	M3D935	N1QIN1	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	TPR_REGION domain-containing protein.	0.913
GET3	N1QJI7_SPHMS	M3D935	N1QJI7	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	DUF410-domain-containing protein.	0.992
GET3	N1QKI0_SPHMS	M3D935	N1QKI0	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.	0.513
M3ARB9_SPHMS	GET3	M3ARB9	M3D935	Protein translocase SEC6.	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	0.457
M3ARB9_SPHMS	M3AT02_SPHMS	M3ARB9	M3AT02	Protein translocase SEC6.	L domain-like protein.	0.937
M3ARB9_SPHMS	M3C0F6_SPHMS	M3ARB9	M3C0F6	Protein translocase SEC6.	Uncharacterized protein.	0.982
M3ARB9_SPHMS	M3C5S5_SPHMS	M3ARB9	M3C5S5	Protein translocase SEC6.	Translocation protein.	0.983
M3ARB9_SPHMS	M3CP32_SPHMS	M3ARB9	M3CP32	Protein translocase SEC6.	SRP9-21 domain-containing protein.	0.742
M3ARB9_SPHMS	M3D3L9_SPHMS	M3ARB9	M3D3L9	Protein translocase SEC6.	Signal recognition particle, SRP9/SRP14 subunit.	0.698
M3ARB9_SPHMS	M3D5V5_SPHMS	M3ARB9	M3D5V5	Protein translocase SEC6.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.998
M3ARB9_SPHMS	M3DAF1_SPHMS	M3ARB9	M3DAF1	Protein translocase SEC6.	J domain-containing protein.	0.960
M3ARB9_SPHMS	N1QFG2_SPHMS	M3ARB9	N1QFG2	Protein translocase SEC6.	SPC12-domain-containing protein.	0.645
M3ARB9_SPHMS	N1QGM6_SPHMS	M3ARB9	N1QGM6	Protein translocase SEC6.	Signal peptidase subunit 3.	0.513
M3ARB9_SPHMS	N1QGM9_SPHMS	M3ARB9	N1QGM9	Protein translocase SEC6.	Protein transport protein SEC61 subunit alpha.	0.997
M3ARB9_SPHMS	N1QI83_SPHMS	M3ARB9	N1QI83	Protein translocase SEC6.	P-loop containing nucleoside triphosphate hydrolase protein.	0.512
M3ARB9_SPHMS	N1QIL7_SPHMS	M3ARB9	N1QIL7	Protein translocase SEC6.	Uncharacterized protein.	0.983
M3ARB9_SPHMS	N1QKI0_SPHMS	M3ARB9	N1QKI0	Protein translocase SEC6.	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.	0.507