108 items (Gasterosteus aculeatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3N5Q3_GASAC	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1263 aa)
	G3N6P1_GASAC	Protein kinase domain-containing protein. (1303 aa)
	G3N7A2_GASAC	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
	G3N7T7_GASAC	Uncharacterized protein. (728 aa)
	G3NB33_GASAC	Integrin, beta-like 1. (496 aa)
	VAV3	Vav guanine nucleotide exchange factor 3. (849 aa)
	G3ND77_GASAC	Tensin 1b. (1663 aa)
	G3NES9_GASAC	B cell linker. (559 aa)
	G3NGQ7_GASAC	Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (452 aa)
	G3NH62_GASAC	Insulin receptor substrate 2b. (1061 aa)
	G3NHN6_GASAC	Tyrosine-protein phosphatase non-receptor type. (388 aa)
	YES1	Tyrosine-protein kinase. (548 aa)
	G3NL63_GASAC	Spire-type actin nucleation factor 1b. (730 aa)
	G3NLI8_GASAC	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1281 aa)
	G3NM14_GASAC	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
	G3NNF0_GASAC	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (473 aa)
	CRK	CRK proto-oncogene, adaptor protein. (309 aa)
	SRC	Tyrosine-protein kinase. (542 aa)
	G3NQ48_GASAC	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	CD3D	Uncharacterized protein. (152 aa)
	G3NRZ9_GASAC	Ig_4 domain-containing protein. (175 aa)
	G3NS42_GASAC	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
	G3NT81_GASAC	Tyrosine-protein kinase. (529 aa)
	G3NTE9_GASAC	Receptor protein-tyrosine kinase. (1329 aa)
	G3NUY1_GASAC	Growth factor receptor-bound protein 2b. (217 aa)
	G3NVW5_GASAC	Receptor protein-tyrosine kinase. (1258 aa)
	G3NW58_GASAC	Tyrosine-protein kinase. (501 aa)
	G3NWI2_GASAC	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa)
	G3NXV3_GASAC	Tyrosine-protein kinase. (581 aa)
	G3NYJ1_GASAC	Protein tyrosine phosphatase receptor type C. (1287 aa)
	G3NZT0_GASAC	Uncharacterized protein. (396 aa)
	G3P1Z5_GASAC	Tyrosine-protein kinase receptor. (1173 aa)
	G3P2K2_GASAC	CD8a molecule. (224 aa)
	G3P2Y7_GASAC	Cbl proto-oncogene, E3 ubiquitin protein ligase. (921 aa)
	G3P3B4_GASAC	Erb-b2 receptor tyrosine kinase 3b. (1341 aa)
	G3P3G3_GASAC	MET proto-oncogene, receptor tyrosine kinase. (1429 aa)
	G3P3G6_GASAC	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (181 aa)
	G3P3H5_GASAC	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (163 aa)
	G3P5R0_GASAC	Tyrosine-protein kinase. (449 aa)
	G3P6Y8_GASAC	Protein tyrosine phosphatase non-receptor type 6. (582 aa)
	G3P7C5_GASAC	Tyrosine-protein kinase. (537 aa)
	G3P7M8_GASAC	Tyrosine-protein kinase. (376 aa)
	G3P7N7_GASAC	Tyrosine-protein kinase. (506 aa)
	G3P8C9_GASAC	Tyrosine-protein kinase receptor. (1366 aa)
	G3P8P8_GASAC	Macrophage stimulating 1 receptor a. (1373 aa)
	G3P984_GASAC	Tyrosine-protein kinase. (463 aa)
	G3P9M3_GASAC	Tyrosine-protein kinase. (487 aa)
	G3PAF6_GASAC	Tyrosine-protein phosphatase domain-containing protein. (125 aa)
	G3PAG2_GASAC	Uncharacterized protein. (239 aa)
	G3PAL9_GASAC	Uncharacterized protein. (1231 aa)
	G3PCE7_GASAC	SHC (Src homology 2 domain containing) transforming protein 2. (591 aa)
	G3PDD6_GASAC	Son of sevenless homolog 2 (Drosophila). (1338 aa)
	G3PDH2_GASAC	Tyrosine-protein phosphatase non-receptor type. (432 aa)
	G3PE85_GASAC	Macrophage stimulating 1 receptor b. (1374 aa)
	G3PEF8_GASAC	SHC (Src homology 2 domain containing) transforming protein 1. (617 aa)
	G3PEL7_GASAC	GRB2-associated binding protein 2. (687 aa)
	G3PGR6_GASAC	GRB2 related adaptor protein a. (215 aa)
	G3PII8_GASAC	Tyrosine-protein kinase receptor. (1413 aa)
	G3PM25_GASAC	Insulin receptor substrate 2a. (1028 aa)
	G3PML0_GASAC	Tensin 1. (1547 aa)
	G3PN00_GASAC	Tyrosine-protein kinase. (513 aa)
	G3PND1_GASAC	Uncharacterized protein. (201 aa)
	G3PND7_GASAC	Uncharacterized protein. (194 aa)
	G3PNI1_GASAC	GRB2 related adaptor protein 2a. (325 aa)
	CSK	Tyrosine-protein kinase. (450 aa)
	G3PPC1_GASAC	Receptor protein-tyrosine kinase. (1283 aa)
	G3PPC2_GASAC	Tyrosine-protein kinase receptor. (1394 aa)
	G3PPI6_GASAC	Tyrosine-protein kinase receptor. (783 aa)
	G3PQU9_GASAC	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1b. (1272 aa)
	G3PRM9_GASAC	Protein tyrosine phosphatase receptor type Sa. (1943 aa)
	G3PS36_GASAC	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (800 aa)
	G3PS87_GASAC	Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (720 aa)
	G3PTE5_GASAC	Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (731 aa)
	G3PTS5_GASAC	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (830 aa)
	G3PU60_GASAC	Rap guanine nucleotide exchange factor (GEF) 1b. (1216 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	G3PUN2_GASAC	Uncharacterized protein. (467 aa)
	G3PVY7_GASAC	Epidermal growth factor. (981 aa)
	SHC3	SHC adaptor protein 3. (580 aa)
	VAV1	Vav guanine nucleotide exchange factor 1. (845 aa)
	G3PWY1_GASAC	Uncharacterized protein. (254 aa)
	G3PX18_GASAC	Vav 3 guanine nucleotide exchange factor b. (849 aa)
	SHC4	SHC adaptor protein 4. (415 aa)
	G3PY71_GASAC	Tyrosine-protein kinase. (548 aa)
	G3PYU2_GASAC	GRB2-associated binding protein 1. (701 aa)
	G3PYZ7_GASAC	Receptor protein-tyrosine kinase. (1207 aa)
	G3PZQ8_GASAC	Tyrosine-protein kinase. (691 aa)
	CTNND1	Catenin delta 1. (921 aa)
	G3Q1Y8_GASAC	Receptor protein-tyrosine kinase. (1139 aa)
	G3Q2C0_GASAC	Vav 2 guanine nucleotide exchange factor. (736 aa)
	G3Q3F0_GASAC	Catenin (cadherin-associated protein), delta 1. (963 aa)
	G3Q3J0_GASAC	Tyrosine-protein kinase. (613 aa)
	G3Q3Q4_GASAC	SH2 domain containing 1A duplicate b. (149 aa)
	G3Q3W4_GASAC	Tyrosine-protein kinase. (636 aa)
	G3Q3W6_GASAC	Tyrosine-protein kinase. (519 aa)
	G3Q425_GASAC	Neuregulin 1. (530 aa)
	G3Q450_GASAC	Tyrosine-protein kinase. (611 aa)
	G3Q488_GASAC	Neuregulin 2b. (764 aa)
	G3Q4B6_GASAC	Insulin receptor substrate 4a. (1058 aa)
	G3Q6P7_GASAC	Uncharacterized protein. (120 aa)
	G3Q6P9_GASAC	IRS-type PTB domain-containing protein. (239 aa)
	G3Q7W3_GASAC	Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (750 aa)
	G3Q979_GASAC	Son of sevenless homolog 1 (Drosophila). (1295 aa)
	G3Q9I3_GASAC	Cbl proto-oncogene B, E3 ubiquitin protein ligase. (980 aa)
	G3QAP8_GASAC	Si:ch211-284e13.4. (802 aa)
	G3QBQ1_GASAC	Neuregulin 2a. (730 aa)
	G3QC36_GASAC	Uncharacterized protein. (885 aa)
	G3QCK8_GASAC	Lymphocyte cytosolic protein 2a. (507 aa)

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD3D	CSK	ENSGACP00000008114	ENSGACP00000019367	Uncharacterized protein.	Tyrosine-protein kinase.	0.704
CD3D	G3N5Q3_GASAC	ENSGACP00000008114	ENSGACP00000000627	Uncharacterized protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.561
CD3D	G3N6P1_GASAC	ENSGACP00000008114	ENSGACP00000000966	Uncharacterized protein.	Protein kinase domain-containing protein.	0.471
CD3D	G3NGQ7_GASAC	ENSGACP00000008114	ENSGACP00000004513	Uncharacterized protein.	Phosphoprotein membrane anchor with glycosphingolipid microdomains 1.	0.674
CD3D	G3NL63_GASAC	ENSGACP00000008114	ENSGACP00000006076	Uncharacterized protein.	Spire-type actin nucleation factor 1b.	0.739
CD3D	G3NLI8_GASAC	ENSGACP00000008114	ENSGACP00000006201	Uncharacterized protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.538
CD3D	G3NM14_GASAC	ENSGACP00000008114	ENSGACP00000006377	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.630
CD3D	G3NRZ9_GASAC	ENSGACP00000008114	ENSGACP00000008116	Uncharacterized protein.	Ig_4 domain-containing protein.	0.999
CD3D	G3NT81_GASAC	ENSGACP00000008114	ENSGACP00000008549	Uncharacterized protein.	Tyrosine-protein kinase.	0.656
CD3D	G3NTE9_GASAC	ENSGACP00000008114	ENSGACP00000008617	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.470
CD3D	G3NUY1_GASAC	ENSGACP00000008114	ENSGACP00000009150	Uncharacterized protein.	Growth factor receptor-bound protein 2b.	0.596
CD3D	G3NVW5_GASAC	ENSGACP00000008114	ENSGACP00000009484	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.470
CD3D	G3NW58_GASAC	ENSGACP00000008114	ENSGACP00000009577	Uncharacterized protein.	Tyrosine-protein kinase.	0.741
CD3D	G3NXV3_GASAC	ENSGACP00000008114	ENSGACP00000010173	Uncharacterized protein.	Tyrosine-protein kinase.	0.969
CD3D	G3NYJ1_GASAC	ENSGACP00000008114	ENSGACP00000010411	Uncharacterized protein.	Protein tyrosine phosphatase receptor type C.	0.842
CD3D	G3P2K2_GASAC	ENSGACP00000008114	ENSGACP00000011825	Uncharacterized protein.	CD8a molecule.	0.968
CD3D	G3P3B4_GASAC	ENSGACP00000008114	ENSGACP00000012087	Uncharacterized protein.	Erb-b2 receptor tyrosine kinase 3b.	0.470
CD3D	G3P5R0_GASAC	ENSGACP00000008114	ENSGACP00000012933	Uncharacterized protein.	Tyrosine-protein kinase.	0.734
CD3D	G3P6Y8_GASAC	ENSGACP00000008114	ENSGACP00000013362	Uncharacterized protein.	Protein tyrosine phosphatase non-receptor type 6.	0.659
CD3D	G3P7C5_GASAC	ENSGACP00000008114	ENSGACP00000013499	Uncharacterized protein.	Tyrosine-protein kinase.	0.656