(12 nodes) Mixed, incl. PI3K p85 subunit, N-terminal SH2 domain, and Insulin receptor substrate network (Gasterosteus aculeatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3NNF0_GASAC	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (473 aa)
	G3NS42_GASAC	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
	G3NWI2_GASAC	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa)
	G3NZT0_GASAC	Uncharacterized protein. (396 aa)
	G3PII8_GASAC	Tyrosine-protein kinase receptor. (1413 aa)
	G3PM25_GASAC	Insulin receptor substrate 2a. (1028 aa)
	G3PTE5_GASAC	Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (731 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	G3PUN2_GASAC	Uncharacterized protein. (467 aa)
	G3Q6P7_GASAC	Uncharacterized protein. (120 aa)
	G3Q6P9_GASAC	IRS-type PTB domain-containing protein. (239 aa)
	G3QAP8_GASAC	Si:ch211-284e13.4. (802 aa)

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G3NNF0_GASAC	G3NS42_GASAC	ENSGACP00000006864	ENSGACP00000008159	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.844
G3NNF0_GASAC	G3NWI2_GASAC	ENSGACP00000006864	ENSGACP00000009701	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.912
G3NNF0_GASAC	G3NZT0_GASAC	ENSGACP00000006864	ENSGACP00000010853	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	Uncharacterized protein.	0.785
G3NNF0_GASAC	G3PII8_GASAC	ENSGACP00000006864	ENSGACP00000017416	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	Tyrosine-protein kinase receptor.	0.829
G3NNF0_GASAC	G3PM25_GASAC	ENSGACP00000006864	ENSGACP00000018656	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	Insulin receptor substrate 2a.	0.903
G3NNF0_GASAC	G3PUN2_GASAC	ENSGACP00000006864	ENSGACP00000021319	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	Uncharacterized protein.	0.787
G3NNF0_GASAC	G3Q6P7_GASAC	ENSGACP00000006864	ENSGACP00000025557	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	Uncharacterized protein.	0.828
G3NNF0_GASAC	G3Q6P9_GASAC	ENSGACP00000006864	ENSGACP00000025559	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	IRS-type PTB domain-containing protein.	0.828
G3NNF0_GASAC	G3QAP8_GASAC	ENSGACP00000006864	ENSGACP00000026964	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	Si:ch211-284e13.4.	0.903
G3NNF0_GASAC	PIK3CA	ENSGACP00000006864	ENSGACP00000021206	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.912
G3NS42_GASAC	G3NNF0_GASAC	ENSGACP00000008159	ENSGACP00000006864	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	0.844
G3NS42_GASAC	G3NZT0_GASAC	ENSGACP00000008159	ENSGACP00000010853	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Uncharacterized protein.	0.935
G3NS42_GASAC	G3PII8_GASAC	ENSGACP00000008159	ENSGACP00000017416	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Tyrosine-protein kinase receptor.	0.808
G3NS42_GASAC	G3PM25_GASAC	ENSGACP00000008159	ENSGACP00000018656	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Insulin receptor substrate 2a.	0.916
G3NS42_GASAC	G3PTE5_GASAC	ENSGACP00000008159	ENSGACP00000020881	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).	0.844
G3NS42_GASAC	G3PUN2_GASAC	ENSGACP00000008159	ENSGACP00000021319	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Uncharacterized protein.	0.935
G3NS42_GASAC	G3Q6P7_GASAC	ENSGACP00000008159	ENSGACP00000025557	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Uncharacterized protein.	0.858
G3NS42_GASAC	G3Q6P9_GASAC	ENSGACP00000008159	ENSGACP00000025559	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	IRS-type PTB domain-containing protein.	0.858
G3NS42_GASAC	G3QAP8_GASAC	ENSGACP00000008159	ENSGACP00000026964	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Si:ch211-284e13.4.	0.910
G3NS42_GASAC	PIK3CA	ENSGACP00000008159	ENSGACP00000021206	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.840