(28 nodes) Cohesin Loading onto Chromatin, and Smc5-Smc6 complex network (Gasterosteus aculeatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3NBB0_GASAC	Uncharacterized protein. (307 aa)
	G3NBB3_GASAC	SCD domain-containing protein. (245 aa)
	G3NDU9_GASAC	Cell division cycle associated 5. (257 aa)
	RAD21	RAD21 cohesin complex component. (641 aa)
	G3NK86_GASAC	Acetyltransf_13 domain-containing protein. (171 aa)
	G3NMV9_GASAC	Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (356 aa)
	G3NS82_GASAC	NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (235 aa)
	G3NSJ5_GASAC	RAD21 cohesin complex component a. (636 aa)
	G3NV44_GASAC	Establishment of sister chromatid cohesion N-acetyltransferase 2. (610 aa)
	G3NY23_GASAC	Nipped-B protein. (2557 aa)
	G3NZW1_GASAC	Structural maintenance of chromosomes 5. (1063 aa)
	G3P2C0_GASAC	Structural maintenance of chromosomes protein. (1231 aa)
	G3P5B9_GASAC	Structural maintenance of chromosomes protein. (1238 aa)
	G3P7Q8_GASAC	WAPL cohesin release factor a. (1185 aa)
	G3P9S2_GASAC	Stromal antigen 1a. (1264 aa)
	G3PC36_GASAC	Si:dkey-119f1.1. (1147 aa)
	G3PCW0_GASAC	Uncharacterized protein. (555 aa)
	G3PCW3_GASAC	Structural maintenance of chromosomes 6. (1039 aa)
	G3PI44_GASAC	MAU2 sister chromatid cohesion factor. (621 aa)
	G3PUS4_GASAC	PDS5 cohesin associated factor A. (1343 aa)
	G3PXA1_GASAC	Nipped-B protein. (2608 aa)
	G3Q3N2_GASAC	Stromal antigen 2b. (1273 aa)
	G3Q473_GASAC	NSE1 homolog, SMC5-SMC6 complex component. (239 aa)
	G3Q478_GASAC	Calcyon neuron-specific vesicular protein. (201 aa)
	G3Q4C7_GASAC	Structural maintenance of chromosomes protein. (1220 aa)
	G3Q7S4_GASAC	Uncharacterized protein. (111 aa)
	G3QAK2_GASAC	Stromal antigen 2a. (1275 aa)
	G3QBA7_GASAC	PDS5 cohesin associated factor B. (1405 aa)

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G3NBB0_GASAC	G3NBB3_GASAC	ENSGACP00000002606	ENSGACP00000002609	Uncharacterized protein.	SCD domain-containing protein.	0.936
G3NBB0_GASAC	G3NDU9_GASAC	ENSGACP00000002606	ENSGACP00000003500	Uncharacterized protein.	Cell division cycle associated 5.	0.811
G3NBB0_GASAC	G3NK86_GASAC	ENSGACP00000002606	ENSGACP00000005748	Uncharacterized protein.	Acetyltransf_13 domain-containing protein.	0.772
G3NBB0_GASAC	G3NS82_GASAC	ENSGACP00000002606	ENSGACP00000008199	Uncharacterized protein.	NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase.	0.683
G3NBB0_GASAC	G3NSJ5_GASAC	ENSGACP00000002606	ENSGACP00000008313	Uncharacterized protein.	RAD21 cohesin complex component a.	0.947
G3NBB0_GASAC	G3NV44_GASAC	ENSGACP00000002606	ENSGACP00000009213	Uncharacterized protein.	Establishment of sister chromatid cohesion N-acetyltransferase 2.	0.772
G3NBB0_GASAC	G3NY23_GASAC	ENSGACP00000002606	ENSGACP00000010243	Uncharacterized protein.	Nipped-B protein.	0.921
G3NBB0_GASAC	G3NZW1_GASAC	ENSGACP00000002606	ENSGACP00000010884	Uncharacterized protein.	Structural maintenance of chromosomes 5.	0.891
G3NBB0_GASAC	G3P2C0_GASAC	ENSGACP00000002606	ENSGACP00000011743	Uncharacterized protein.	Structural maintenance of chromosomes protein.	0.975
G3NBB0_GASAC	G3P5B9_GASAC	ENSGACP00000002606	ENSGACP00000012792	Uncharacterized protein.	Structural maintenance of chromosomes protein.	0.975
G3NBB0_GASAC	G3P7Q8_GASAC	ENSGACP00000002606	ENSGACP00000013632	Uncharacterized protein.	WAPL cohesin release factor a.	0.843
G3NBB0_GASAC	G3P9S2_GASAC	ENSGACP00000002606	ENSGACP00000014346	Uncharacterized protein.	Stromal antigen 1a.	0.622
G3NBB0_GASAC	G3PC36_GASAC	ENSGACP00000002606	ENSGACP00000015160	Uncharacterized protein.	Si:dkey-119f1.1.	0.868
G3NBB0_GASAC	G3PCW0_GASAC	ENSGACP00000002606	ENSGACP00000015434	Uncharacterized protein.	Uncharacterized protein.	0.898
G3NBB0_GASAC	G3PCW3_GASAC	ENSGACP00000002606	ENSGACP00000015437	Uncharacterized protein.	Structural maintenance of chromosomes 6.	0.872
G3NBB0_GASAC	G3PI44_GASAC	ENSGACP00000002606	ENSGACP00000017271	Uncharacterized protein.	MAU2 sister chromatid cohesion factor.	0.742
G3NBB0_GASAC	G3PUS4_GASAC	ENSGACP00000002606	ENSGACP00000021361	Uncharacterized protein.	PDS5 cohesin associated factor A.	0.930
G3NBB0_GASAC	G3PXA1_GASAC	ENSGACP00000002606	ENSGACP00000022240	Uncharacterized protein.	Nipped-B protein.	0.921
G3NBB0_GASAC	G3Q3N2_GASAC	ENSGACP00000002606	ENSGACP00000024484	Uncharacterized protein.	Stromal antigen 2b.	0.625
G3NBB0_GASAC	G3Q4C7_GASAC	ENSGACP00000002606	ENSGACP00000024731	Uncharacterized protein.	Structural maintenance of chromosomes protein.	0.982