(22 nodes) PDGF/VEGF domain, and Tyrosine-protein kinase, receptor class III, conserved site network (Gasterosteus aculeatus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Your Input:
	G3N8C7_GASAC	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (235 aa)
	G3NEH6_GASAC	Colony stimulating factor 1b (macrophage). (270 aa)
	G3NFC6_GASAC	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1136 aa)
	G3NWP9_GASAC	Angiopoietin 2b. (506 aa)
	G3NYI4_GASAC	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (150 aa)
	G3NZH9_GASAC	Platelet derived growth factor d. (337 aa)
	G3P069_GASAC	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (243 aa)
	G3PBV5_GASAC	Platelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family. (234 aa)
	G3PGI4_GASAC	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (712 aa)
	G3PJA4_GASAC	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (191 aa)
	G3PMK6_GASAC	Platelet-derived growth factor receptor, alpha polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1066 aa)
	G3PMN1_GASAC	Kinase insert domain receptor (a type III receptor tyrosine kinase). (1307 aa)
	G3PQQ8_GASAC	Pirin; Belongs to the pirin family. (294 aa)
	G3PQR2_GASAC	Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (309 aa)
	G3PUW0_GASAC	Tyrosine-protein kinase receptor. (804 aa)
	G3PVJ6_GASAC	Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family. (357 aa)
	G3PW69_GASAC	Platelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family. (305 aa)
	G3Q1P0_GASAC	Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1044 aa)
	G3Q1P6_GASAC	Colony stimulating factor 1 receptor, a; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (974 aa)
	G3Q2X3_GASAC	Fms-related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1378 aa)
	G3Q8D9_GASAC	Hepatocyte growth factor a; Belongs to the peptidase S1 family. Plasminogen subfamily. (705 aa)
	G3QCN7_GASAC	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (988 aa)

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G3N8C7_GASAC	G3NFC6_GASAC	ENSGACP00000001561	ENSGACP00000004028	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.923
G3N8C7_GASAC	G3NYI4_GASAC	ENSGACP00000001561	ENSGACP00000010404	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	0.865
G3N8C7_GASAC	G3NZH9_GASAC	ENSGACP00000001561	ENSGACP00000010752	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Platelet derived growth factor d.	0.903
G3N8C7_GASAC	G3PBV5_GASAC	ENSGACP00000001561	ENSGACP00000015079	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Platelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family.	0.933
G3N8C7_GASAC	G3PGI4_GASAC	ENSGACP00000001561	ENSGACP00000016708	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.792
G3N8C7_GASAC	G3PJA4_GASAC	ENSGACP00000001561	ENSGACP00000017683	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	0.862
G3N8C7_GASAC	G3PMK6_GASAC	ENSGACP00000001561	ENSGACP00000018837	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Platelet-derived growth factor receptor, alpha polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.936
G3N8C7_GASAC	G3PMN1_GASAC	ENSGACP00000001561	ENSGACP00000018862	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Kinase insert domain receptor (a type III receptor tyrosine kinase).	0.812
G3N8C7_GASAC	G3PQQ8_GASAC	ENSGACP00000001561	ENSGACP00000019943	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Pirin; Belongs to the pirin family.	0.737
G3N8C7_GASAC	G3PQR2_GASAC	ENSGACP00000001561	ENSGACP00000019947	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family.	0.852
G3N8C7_GASAC	G3PUW0_GASAC	ENSGACP00000001561	ENSGACP00000021397	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Tyrosine-protein kinase receptor.	0.717
G3N8C7_GASAC	G3PVJ6_GASAC	ENSGACP00000001561	ENSGACP00000021634	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family.	0.874
G3N8C7_GASAC	G3PW69_GASAC	ENSGACP00000001561	ENSGACP00000021858	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Platelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family.	0.909
G3N8C7_GASAC	G3Q1P0_GASAC	ENSGACP00000001561	ENSGACP00000023788	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.990
G3N8C7_GASAC	G3Q1P6_GASAC	ENSGACP00000001561	ENSGACP00000023794	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Colony stimulating factor 1 receptor, a; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.898
G3N8C7_GASAC	G3Q2X3_GASAC	ENSGACP00000001561	ENSGACP00000024222	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Fms-related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.812
G3N8C7_GASAC	G3Q8D9_GASAC	ENSGACP00000001561	ENSGACP00000026153	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Hepatocyte growth factor a; Belongs to the peptidase S1 family. Plasminogen subfamily.	0.640
G3N8C7_GASAC	G3QCN7_GASAC	ENSGACP00000001561	ENSGACP00000027653	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.898
G3NEH6_GASAC	G3NFC6_GASAC	ENSGACP00000003727	ENSGACP00000004028	Colony stimulating factor 1b (macrophage).	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.918
G3NEH6_GASAC	G3PMK6_GASAC	ENSGACP00000003727	ENSGACP00000018837	Colony stimulating factor 1b (macrophage).	Platelet-derived growth factor receptor, alpha polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.897