(18 nodes) U2 snRNP, and U1 snRNA binding network (Gasterosteus aculeatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3N4K0_GASAC	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46. (1012 aa)
	G3NDR5_GASAC	Splicing factor 3b, subunit 3. (1218 aa)
	G3NG36_GASAC	Small nuclear ribonucleoprotein-associated protein. (238 aa)
	G3NI77_GASAC	Splicing factor 3b, subunit 4. (395 aa)
	G3NLV0_GASAC	PHD finger protein 5A. (111 aa)
	G3NLZ7_GASAC	Splicing factor 3b, subunit 6. (125 aa)
	SNRPC	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (149 aa)
	SNRPD1	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (119 aa)
	G3NU46_GASAC	Small nuclear ribonucleoprotein Sm D2. (118 aa)
	G3NYT4_GASAC	Splicing factor 3a, subunit 3. (501 aa)
	G3P253_GASAC	Splicing factor 3b, subunit 1. (1312 aa)
	G3P5Y3_GASAC	Small nuclear ribonucleoprotein polypeptide A. (277 aa)
	G3P7W6_GASAC	Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
	G3PDS4_GASAC	Splicing factor 3a, subunit 1. (785 aa)
	G3PLX6_GASAC	Small nuclear ribonucleoprotein polypeptide A. (294 aa)
	G3PR91_GASAC	Splicing factor 3a, subunit 2. (292 aa)
	G3PZX4_GASAC	Small nuclear ribonucleoprotein Sm D3. (128 aa)
	G3Q5I4_GASAC	Splicing factor 3b, subunit 2. (655 aa)

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G3N4K0_GASAC	G3NDR5_GASAC	ENSGACP00000000220	ENSGACP00000003465	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46.	Splicing factor 3b, subunit 3.	0.997
G3N4K0_GASAC	G3NG36_GASAC	ENSGACP00000000220	ENSGACP00000004291	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46.	Small nuclear ribonucleoprotein-associated protein.	0.947
G3N4K0_GASAC	G3NI77_GASAC	ENSGACP00000000220	ENSGACP00000005037	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46.	Splicing factor 3b, subunit 4.	0.987
G3N4K0_GASAC	G3NLV0_GASAC	ENSGACP00000000220	ENSGACP00000006313	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46.	PHD finger protein 5A.	0.997
G3N4K0_GASAC	G3NLZ7_GASAC	ENSGACP00000000220	ENSGACP00000006360	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46.	Splicing factor 3b, subunit 6.	0.945
G3N4K0_GASAC	G3NU46_GASAC	ENSGACP00000000220	ENSGACP00000008864	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46.	Small nuclear ribonucleoprotein Sm D2.	0.982
G3N4K0_GASAC	G3NYT4_GASAC	ENSGACP00000000220	ENSGACP00000010505	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46.	Splicing factor 3a, subunit 3.	0.998
G3N4K0_GASAC	G3P253_GASAC	ENSGACP00000000220	ENSGACP00000011676	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46.	Splicing factor 3b, subunit 1.	0.998
G3N4K0_GASAC	G3P5Y3_GASAC	ENSGACP00000000220	ENSGACP00000013006	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46.	Small nuclear ribonucleoprotein polypeptide A.	0.962
G3N4K0_GASAC	G3P7W6_GASAC	ENSGACP00000000220	ENSGACP00000013690	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46.	Splicing factor 3B subunit 5; Belongs to the SF3B5 family.	0.998
G3N4K0_GASAC	G3PDS4_GASAC	ENSGACP00000000220	ENSGACP00000015748	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46.	Splicing factor 3a, subunit 1.	0.998
G3N4K0_GASAC	G3PLX6_GASAC	ENSGACP00000000220	ENSGACP00000018607	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46.	Small nuclear ribonucleoprotein polypeptide A.	0.996
G3N4K0_GASAC	G3PR91_GASAC	ENSGACP00000000220	ENSGACP00000020126	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46.	Splicing factor 3a, subunit 2.	0.998
G3N4K0_GASAC	G3PZX4_GASAC	ENSGACP00000000220	ENSGACP00000023164	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46.	Small nuclear ribonucleoprotein Sm D3.	0.977
G3N4K0_GASAC	G3Q5I4_GASAC	ENSGACP00000000220	ENSGACP00000025140	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46.	Splicing factor 3b, subunit 2.	0.992
G3N4K0_GASAC	SNRPC	ENSGACP00000000220	ENSGACP00000006468	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46.	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...]	0.937
G3N4K0_GASAC	SNRPD1	ENSGACP00000000220	ENSGACP00000006899	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46.	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	0.996
G3NDR5_GASAC	G3N4K0_GASAC	ENSGACP00000003465	ENSGACP00000000220	Splicing factor 3b, subunit 3.	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46.	0.997
G3NDR5_GASAC	G3NG36_GASAC	ENSGACP00000003465	ENSGACP00000004291	Splicing factor 3b, subunit 3.	Small nuclear ribonucleoprotein-associated protein.	0.976
G3NDR5_GASAC	G3NI77_GASAC	ENSGACP00000003465	ENSGACP00000005037	Splicing factor 3b, subunit 3.	Splicing factor 3b, subunit 4.	0.999