(50 nodes) Wnt signaling pathway, and Wnt protein secretion network (Gasterosteus aculeatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3N468_GASAC	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (182 aa)
	G3N682_GASAC	Low density lipoprotein receptor-related protein 1Aa. (4519 aa)
	G3N6B9_GASAC	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (317 aa)
	G3NAG3_GASAC	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. (239 aa)
	G3NBP6_GASAC	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (572 aa)
	G3NHP6_GASAC	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	G3NHR3_GASAC	Receptor like tyrosine kinase. (560 aa)
	G3NI00_GASAC	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (333 aa)
	G3NIT3_GASAC	Sizzled. (299 aa)
	G3NLK4_GASAC	Frizzled class receptor 3a; Belongs to the G-protein coupled receptor Fz/Smo family. (302 aa)
	G3NMF6_GASAC	Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (623 aa)
	G3NPL5_GASAC	Secreted frizzled-related protein 1a. (318 aa)
	G3NRX3_GASAC	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
	G3NV22_GASAC	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (532 aa)
	G3NVJ9_GASAC	Receptor tyrosine kinase-like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (901 aa)
	G3NXL2_GASAC	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (314 aa)
	G3NXM0_GASAC	Frizzled class receptor 9b; Belongs to the G-protein coupled receptor Fz/Smo family. (577 aa)
	G3NXV6_GASAC	Secreted frizzled-related protein 5. (387 aa)
	G3NYG6_GASAC	Uncharacterized protein. (303 aa)
	G3NZ94_GASAC	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (533 aa)
	G3NZQ3_GASAC	Frizzled related protein. (315 aa)
	G3P0U0_GASAC	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
	G3P0Z0_GASAC	Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (370 aa)
	G3P314_GASAC	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
	G3P352_GASAC	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
	G3P354_GASAC	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (429 aa)
	G3P3W9_GASAC	Low density lipoprotein receptor-related protein 1Ab. (4508 aa)
	WNT2B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (387 aa)
	G3P6V6_GASAC	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (327 aa)
	G3P730_GASAC	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (379 aa)
	G3PA01_GASAC	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
	WNT7A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
	G3PEV7_GASAC	Porcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (457 aa)
	G3PEZ2_GASAC	Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (449 aa)
	G3PH50_GASAC	Uncharacterized protein; Belongs to the membrane-bound acyltransferase family. (451 aa)
	G3PMA2_GASAC	Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (525 aa)
	G3PMA4_GASAC	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
	G3PRW0_GASAC	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (500 aa)
	G3PSM8_GASAC	Wnt ligand secretion mediator. (542 aa)
	FZD3	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (684 aa)
	G3PXA7_GASAC	Secreted frizzled-related protein 2. (295 aa)
	G3PZJ6_GASAC	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	G3Q0M2_GASAC	Uncharacterized protein. (85 aa)
	G3Q3H4_GASAC	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
	G3Q3I0_GASAC	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (412 aa)
	G3Q468_GASAC	Receptor tyrosine kinase-like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (892 aa)
	G3Q5B1_GASAC	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	G3Q764_GASAC	DAN domain family, member 5. (253 aa)
	G3Q7X1_GASAC	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (371 aa)
	G3Q9W2_GASAC	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FZD3	G3N468_GASAC	ENSGACP00000021441	ENSGACP00000000086	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.856
FZD3	G3N682_GASAC	ENSGACP00000021441	ENSGACP00000000806	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Low density lipoprotein receptor-related protein 1Aa.	0.629
FZD3	G3N6B9_GASAC	ENSGACP00000021441	ENSGACP00000000844	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.925
FZD3	G3NAG3_GASAC	ENSGACP00000021441	ENSGACP00000002308	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family.	0.604
FZD3	G3NBP6_GASAC	ENSGACP00000021441	ENSGACP00000002743	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family.	0.615
FZD3	G3NHP6_GASAC	ENSGACP00000021441	ENSGACP00000004855	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.917
FZD3	G3NHR3_GASAC	ENSGACP00000021441	ENSGACP00000004873	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Receptor like tyrosine kinase.	0.888
FZD3	G3NI00_GASAC	ENSGACP00000021441	ENSGACP00000004960	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.913
FZD3	G3NIT3_GASAC	ENSGACP00000021441	ENSGACP00000005243	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Sizzled.	0.691
FZD3	G3NPL5_GASAC	ENSGACP00000021441	ENSGACP00000007279	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 1a.	0.874
FZD3	G3NRX3_GASAC	ENSGACP00000021441	ENSGACP00000008090	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.911
FZD3	G3NV22_GASAC	ENSGACP00000021441	ENSGACP00000009191	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.580
FZD3	G3NVJ9_GASAC	ENSGACP00000021441	ENSGACP00000009368	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Receptor tyrosine kinase-like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.806
FZD3	G3NXL2_GASAC	ENSGACP00000021441	ENSGACP00000010081	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.920
FZD3	G3NXM0_GASAC	ENSGACP00000021441	ENSGACP00000010090	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 9b; Belongs to the G-protein coupled receptor Fz/Smo family.	0.601
FZD3	G3NXV6_GASAC	ENSGACP00000021441	ENSGACP00000010176	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 5.	0.874
FZD3	G3NYG6_GASAC	ENSGACP00000021441	ENSGACP00000010386	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.751
FZD3	G3NZ94_GASAC	ENSGACP00000021441	ENSGACP00000010666	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.677
FZD3	G3NZQ3_GASAC	ENSGACP00000021441	ENSGACP00000010826	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled related protein.	0.791
FZD3	G3P0U0_GASAC	ENSGACP00000021441	ENSGACP00000011213	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.908