(12 nodes) interleukin-1-mediated signaling pathway, and interleukin-1 receptor activity network (Gasterosteus aculeatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3N843_GASAC	Uncharacterized protein. (206 aa)
	G3N846_GASAC	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (498 aa)
	G3N8T7_GASAC	Ig-like domain-containing protein. (251 aa)
	G3N8T9_GASAC	Uncharacterized protein. (171 aa)
	G3N8U3_GASAC	Uncharacterized protein. (545 aa)
	G3N8U6_GASAC	Uncharacterized protein. (263 aa)
	G3NH35_GASAC	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (297 aa)
	G3NJ16_GASAC	Interleukin-1 receptor-associated kinase 4. (485 aa)
	G3NKE5_GASAC	Uncharacterized protein. (571 aa)
	G3NTJ8_GASAC	TIR domain-containing protein. (52 aa)
	il1b	Interleukin-1. (262 aa)
	G3Q6J0_GASAC	Interleukin-1 receptor-associated kinase 3. (527 aa)

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G3N843_GASAC	G3N846_GASAC	ENSGACP00000001477	ENSGACP00000001480	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.847
G3N843_GASAC	G3N8T7_GASAC	ENSGACP00000001477	ENSGACP00000001724	Uncharacterized protein.	Ig-like domain-containing protein.	0.835
G3N843_GASAC	G3N8T9_GASAC	ENSGACP00000001477	ENSGACP00000001726	Uncharacterized protein.	Uncharacterized protein.	0.835
G3N843_GASAC	G3N8U3_GASAC	ENSGACP00000001477	ENSGACP00000001730	Uncharacterized protein.	Uncharacterized protein.	0.835
G3N843_GASAC	G3N8U6_GASAC	ENSGACP00000001477	ENSGACP00000001733	Uncharacterized protein.	Uncharacterized protein.	0.714
G3N843_GASAC	G3NH35_GASAC	ENSGACP00000001477	ENSGACP00000004643	Uncharacterized protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.989
G3N843_GASAC	G3NJ16_GASAC	ENSGACP00000001477	ENSGACP00000005326	Uncharacterized protein.	Interleukin-1 receptor-associated kinase 4.	0.982
G3N843_GASAC	G3NKE5_GASAC	ENSGACP00000001477	ENSGACP00000005807	Uncharacterized protein.	Uncharacterized protein.	0.808
G3N843_GASAC	G3NTJ8_GASAC	ENSGACP00000001477	ENSGACP00000008666	Uncharacterized protein.	TIR domain-containing protein.	0.938
G3N843_GASAC	G3Q6J0_GASAC	ENSGACP00000001477	ENSGACP00000025500	Uncharacterized protein.	Interleukin-1 receptor-associated kinase 3.	0.956
G3N843_GASAC	il1b	ENSGACP00000001477	ENSGACP00000019287	Uncharacterized protein.	Interleukin-1.	0.745
G3N846_GASAC	G3N843_GASAC	ENSGACP00000001480	ENSGACP00000001477	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.847
G3N846_GASAC	G3N8T7_GASAC	ENSGACP00000001480	ENSGACP00000001724	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Ig-like domain-containing protein.	0.835
G3N846_GASAC	G3N8T9_GASAC	ENSGACP00000001480	ENSGACP00000001726	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.835
G3N846_GASAC	G3N8U3_GASAC	ENSGACP00000001480	ENSGACP00000001730	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.840
G3N846_GASAC	G3N8U6_GASAC	ENSGACP00000001480	ENSGACP00000001733	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.714
G3N846_GASAC	G3NH35_GASAC	ENSGACP00000001480	ENSGACP00000004643	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.989
G3N846_GASAC	G3NJ16_GASAC	ENSGACP00000001480	ENSGACP00000005326	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Interleukin-1 receptor-associated kinase 4.	0.984
G3N846_GASAC	G3NKE5_GASAC	ENSGACP00000001480	ENSGACP00000005807	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.808
G3N846_GASAC	G3NTJ8_GASAC	ENSGACP00000001480	ENSGACP00000008666	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	TIR domain-containing protein.	0.938