28 items (Gasterosteus aculeatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	G3NJV2_GASAC	Serpin peptidase inhibitor, clade D (heparin cofactor), member 1; Belongs to the serpin family. (503 aa)
	G3NM02_GASAC	Uncharacterized protein. (245 aa)
	G3NMM5_GASAC	SERPIN domain-containing protein; Belongs to the serpin family. (415 aa)
	G3NQA7_GASAC	Uncharacterized protein. (321 aa)
	G3NQL5_GASAC	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (264 aa)
	G3NR28_GASAC	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (808 aa)
	G3NZC7_GASAC	Si:ch1073-416d2.3; Belongs to the serpin family. (408 aa)
	G3P3P6_GASAC	Coagulation factor V; Belongs to the multicopper oxidase family. (1449 aa)
	G3P9W0_GASAC	SERPIN domain-containing protein; Belongs to the serpin family. (478 aa)
	G3PCV6_GASAC	SERPIN domain-containing protein; Belongs to the serpin family. (426 aa)
	G3PD51_GASAC	SERPIN domain-containing protein; Belongs to the serpin family. (419 aa)
	G3PK17_GASAC	Serpin peptidase inhibitor, clade C (antithrombin), member 1; Belongs to the serpin family. (453 aa)
	G3PQW7_GASAC	Carboxypeptidase B2 (plasma). (419 aa)
	G3PRF1_GASAC	Protein S. (678 aa)
	G3PRZ3_GASAC	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (618 aa)
	G3PS25_GASAC	Coagulation factor VII. (440 aa)
	G3PS27_GASAC	Coagulation factor VIIi. (457 aa)
	G3PS47_GASAC	Coagulation factor X. (498 aa)
	G3PT67_GASAC	Uncharacterized protein. (435 aa)
	G3PUE6_GASAC	Alpha-2-HS-glycoprotein 2. (347 aa)
	G3PXC5_GASAC	Fibrinogen gamma chain. (428 aa)
	G3PZK5_GASAC	Alpha-1-microglobulin/bikunin precursor. (354 aa)
	APOH	Apolipoprotein H. (351 aa)
	APOH-2	Apolipoprotein H. (359 aa)
	G3Q4A0_GASAC	Fibrinogen beta chain. (499 aa)
	G3Q4A9_GASAC	Fibrinogen alpha chain. (622 aa)
	G3Q9U9_GASAC	Peptidase S1 domain-containing protein. (311 aa)
	G3QAX5_GASAC	Coagulation factor IXb. (547 aa)

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APOH	G3NJV2_GASAC	ENSGACP00000024478	ENSGACP00000005614	Apolipoprotein H.	Serpin peptidase inhibitor, clade D (heparin cofactor), member 1; Belongs to the serpin family.	0.688
APOH	G3NM02_GASAC	ENSGACP00000024478	ENSGACP00000006365	Apolipoprotein H.	Uncharacterized protein.	0.510
APOH	G3NMM5_GASAC	ENSGACP00000024478	ENSGACP00000006588	Apolipoprotein H.	SERPIN domain-containing protein; Belongs to the serpin family.	0.523
APOH	G3NQA7_GASAC	ENSGACP00000024478	ENSGACP00000007523	Apolipoprotein H.	Uncharacterized protein.	0.745
APOH	G3NR28_GASAC	ENSGACP00000024478	ENSGACP00000007794	Apolipoprotein H.	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.841
APOH	G3NZC7_GASAC	ENSGACP00000024478	ENSGACP00000010699	Apolipoprotein H.	Si:ch1073-416d2.3; Belongs to the serpin family.	0.573
APOH	G3P9W0_GASAC	ENSGACP00000024478	ENSGACP00000014384	Apolipoprotein H.	SERPIN domain-containing protein; Belongs to the serpin family.	0.633
APOH	G3PCV6_GASAC	ENSGACP00000024478	ENSGACP00000015430	Apolipoprotein H.	SERPIN domain-containing protein; Belongs to the serpin family.	0.518
APOH	G3PD51_GASAC	ENSGACP00000024478	ENSGACP00000015525	Apolipoprotein H.	SERPIN domain-containing protein; Belongs to the serpin family.	0.525
APOH	G3PK17_GASAC	ENSGACP00000024478	ENSGACP00000017947	Apolipoprotein H.	Serpin peptidase inhibitor, clade C (antithrombin), member 1; Belongs to the serpin family.	0.860
APOH	G3PQW7_GASAC	ENSGACP00000024478	ENSGACP00000020002	Apolipoprotein H.	Carboxypeptidase B2 (plasma).	0.473
APOH	G3PRZ3_GASAC	ENSGACP00000024478	ENSGACP00000020379	Apolipoprotein H.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.885
APOH	G3PS25_GASAC	ENSGACP00000024478	ENSGACP00000020411	Apolipoprotein H.	Coagulation factor VII.	0.563
APOH	G3PS47_GASAC	ENSGACP00000024478	ENSGACP00000020433	Apolipoprotein H.	Coagulation factor X.	0.561
APOH	G3PT67_GASAC	ENSGACP00000024478	ENSGACP00000020803	Apolipoprotein H.	Uncharacterized protein.	0.704
APOH	G3PUE6_GASAC	ENSGACP00000024478	ENSGACP00000021233	Apolipoprotein H.	Alpha-2-HS-glycoprotein 2.	0.871
APOH	G3PXC5_GASAC	ENSGACP00000024478	ENSGACP00000022264	Apolipoprotein H.	Fibrinogen gamma chain.	0.843
APOH	G3PZK5_GASAC	ENSGACP00000024478	ENSGACP00000023045	Apolipoprotein H.	Alpha-1-microglobulin/bikunin precursor.	0.811
APOH	G3Q4A0_GASAC	ENSGACP00000024478	ENSGACP00000024704	Apolipoprotein H.	Fibrinogen beta chain.	0.694
APOH	G3Q4A9_GASAC	ENSGACP00000024478	ENSGACP00000024713	Apolipoprotein H.	Fibrinogen alpha chain.	0.821