(12 nodes) Rap1 signalling, and Ras-related protein Rap2 network (Gasterosteus aculeatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3NG66_GASAC	Uncharacterized protein. (199 aa)
	G3NM08_GASAC	Rap guanine nucleotide exchange factor (GEF) 4. (1011 aa)
	G3NM27_GASAC	Rap-GAP domain-containing protein. (608 aa)
	RAPGEF5	Rap guanine nucleotide exchange factor 5. (774 aa)
	G3NSC5_GASAC	RAP1 GTPase activating protein 2a. (524 aa)
	G3P5L5_GASAC	Signal-induced proliferation-associated 1 like 3. (1707 aa)
	RAP2B	RAP2B, member of RAS oncogene family. (183 aa)
	G3P981_GASAC	DIRAS family, GTP-binding RAS-like 1b. (198 aa)
	G3PAC4_GASAC	Rap guanine nucleotide exchange factor (GEF) 3. (874 aa)
	G3PFF2_GASAC	RAP1 GTPase activating protein. (695 aa)
	G3PQB7_GASAC	RAP2B, member of RAS oncogene family. (182 aa)
	G3PRT7_GASAC	Zgc:171558. (1002 aa)

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G3NG66_GASAC	G3NM08_GASAC	ENSGACP00000004321	ENSGACP00000006371	Uncharacterized protein.	Rap guanine nucleotide exchange factor (GEF) 4.	0.830
G3NG66_GASAC	G3NM27_GASAC	ENSGACP00000004321	ENSGACP00000006390	Uncharacterized protein.	Rap-GAP domain-containing protein.	0.778
G3NG66_GASAC	G3NSC5_GASAC	ENSGACP00000004321	ENSGACP00000008242	Uncharacterized protein.	RAP1 GTPase activating protein 2a.	0.778
G3NG66_GASAC	G3P5L5_GASAC	ENSGACP00000004321	ENSGACP00000012888	Uncharacterized protein.	Signal-induced proliferation-associated 1 like 3.	0.674
G3NG66_GASAC	G3PAC4_GASAC	ENSGACP00000004321	ENSGACP00000014548	Uncharacterized protein.	Rap guanine nucleotide exchange factor (GEF) 3.	0.746
G3NG66_GASAC	G3PFF2_GASAC	ENSGACP00000004321	ENSGACP00000016326	Uncharacterized protein.	RAP1 GTPase activating protein.	0.778
G3NG66_GASAC	G3PRT7_GASAC	ENSGACP00000004321	ENSGACP00000020323	Uncharacterized protein.	Zgc:171558.	0.830
G3NG66_GASAC	RAPGEF5	ENSGACP00000004321	ENSGACP00000008098	Uncharacterized protein.	Rap guanine nucleotide exchange factor 5.	0.666
G3NM08_GASAC	G3NG66_GASAC	ENSGACP00000006371	ENSGACP00000004321	Rap guanine nucleotide exchange factor (GEF) 4.	Uncharacterized protein.	0.830
G3NM08_GASAC	G3NM27_GASAC	ENSGACP00000006371	ENSGACP00000006390	Rap guanine nucleotide exchange factor (GEF) 4.	Rap-GAP domain-containing protein.	0.694
G3NM08_GASAC	G3NSC5_GASAC	ENSGACP00000006371	ENSGACP00000008242	Rap guanine nucleotide exchange factor (GEF) 4.	RAP1 GTPase activating protein 2a.	0.694
G3NM08_GASAC	G3P5L5_GASAC	ENSGACP00000006371	ENSGACP00000012888	Rap guanine nucleotide exchange factor (GEF) 4.	Signal-induced proliferation-associated 1 like 3.	0.529
G3NM08_GASAC	G3P981_GASAC	ENSGACP00000006371	ENSGACP00000014155	Rap guanine nucleotide exchange factor (GEF) 4.	DIRAS family, GTP-binding RAS-like 1b.	0.830
G3NM08_GASAC	G3PAC4_GASAC	ENSGACP00000006371	ENSGACP00000014548	Rap guanine nucleotide exchange factor (GEF) 4.	Rap guanine nucleotide exchange factor (GEF) 3.	0.854
G3NM08_GASAC	G3PFF2_GASAC	ENSGACP00000006371	ENSGACP00000016326	Rap guanine nucleotide exchange factor (GEF) 4.	RAP1 GTPase activating protein.	0.694
G3NM08_GASAC	G3PQB7_GASAC	ENSGACP00000006371	ENSGACP00000019802	Rap guanine nucleotide exchange factor (GEF) 4.	RAP2B, member of RAS oncogene family.	0.830
G3NM08_GASAC	G3PRT7_GASAC	ENSGACP00000006371	ENSGACP00000020323	Rap guanine nucleotide exchange factor (GEF) 4.	Zgc:171558.	0.842
G3NM08_GASAC	RAP2B	ENSGACP00000006371	ENSGACP00000013559	Rap guanine nucleotide exchange factor (GEF) 4.	RAP2B, member of RAS oncogene family.	0.830
G3NM27_GASAC	G3NG66_GASAC	ENSGACP00000006390	ENSGACP00000004321	Rap-GAP domain-containing protein.	Uncharacterized protein.	0.778
G3NM27_GASAC	G3NM08_GASAC	ENSGACP00000006390	ENSGACP00000006371	Rap-GAP domain-containing protein.	Rap guanine nucleotide exchange factor (GEF) 4.	0.694