STRINGSTRING
KLHL12 KLHL12 G3PH53_GASAC G3PH53_GASAC CDH2 CDH2 G3PXA7_GASAC G3PXA7_GASAC G3Q0N4_GASAC G3Q0N4_GASAC G3Q2H2_GASAC G3Q2H2_GASAC G3Q5D8_GASAC G3Q5D8_GASAC G3Q7H1_GASAC G3Q7H1_GASAC G3Q7X1_GASAC G3Q7X1_GASAC G3Q976_GASAC G3Q976_GASAC G3QBY8_GASAC G3QBY8_GASAC G3P730_GASAC G3P730_GASAC G3NYG6_GASAC G3NYG6_GASAC G3NXT1_GASAC G3NXT1_GASAC G3NRM9_GASAC G3NRM9_GASAC G3NPS6_GASAC G3NPS6_GASAC PTK7 PTK7 G3NES8_GASAC G3NES8_GASAC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KLHL12Kelch like family member 12. (568 aa)
G3PH53_GASACTransforming growth factor beta; Belongs to the TGF-beta family. (395 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (847 aa)
G3PXA7_GASACSecreted frizzled-related protein 2. (295 aa)
G3Q0N4_GASACVang-like protein. (579 aa)
G3Q2H2_GASACMultifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
G3Q5D8_GASACVang-like protein. (524 aa)
G3Q7H1_GASACAdhesion G protein-coupled receptor A3; Belongs to the G-protein coupled receptor 2 family. (1341 aa)
G3Q7X1_GASACProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (371 aa)
G3Q976_GASACProtein phosphatase 1 regulatory subunit. (1030 aa)
G3QBY8_GASACMultifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (151 aa)
G3P730_GASACProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (379 aa)
G3NYG6_GASACUncharacterized protein. (303 aa)
G3NXT1_GASACT-box transcription factor Ta. (429 aa)
G3NRM9_GASACMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1635 aa)
G3NPS6_GASACProtein phosphatase 1 regulatory subunit. (1025 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1053 aa)
G3NES8_GASACCadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins. (772 aa)
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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