(47 nodes) Regulation of epithelial to mesenchymal transition network (Gasterosteus aculeatus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3PRQ8_GASAC	Eph receptor A4b. (980 aa)
	ZNF703	Zinc finger protein 703. (580 aa)
	G3PTI9_GASAC	DAB adaptor protein 2. (764 aa)
	G3PXA7_GASAC	Secreted frizzled-related protein 2. (295 aa)
	SMAD4	Mothers against decapentaplegic homolog. (526 aa)
	G3PXS7_GASAC	Transforming growth factor beta; Belongs to the TGF-beta family. (418 aa)
	G3PZN0_GASAC	Lymphoid enhancer-binding factor 1. (364 aa)
	CRB2	Uncharacterized protein. (1239 aa)
	G3QAS3_GASAC	Pleckstrin homology-like domain, family B, member 1a. (1231 aa)
	G3QBR8_GASAC	Pleckstrin homology-like domain, family B, member 2a. (717 aa)
	G3PE86_GASAC	Ephrin-A1b; Belongs to the ephrin family. (237 aa)
	G3PH53_GASAC	Transforming growth factor beta; Belongs to the TGF-beta family. (395 aa)
	G3PI25_GASAC	Goosecoid. (241 aa)
	G3PI70_GASAC	Sprouty related EVH1 domain containing 3. (411 aa)
	G3PIY0_GASAC	Zinc finger protein 703. (586 aa)
	G3PJ53_GASAC	MAPK regulated corepressor interacting protein 1. (113 aa)
	G3PLV4_GASAC	Transforming growth factor beta; Belongs to the TGF-beta family. (436 aa)
	G3PMZ4_GASAC	Epithelial membrane protein 2. (96 aa)
	il1b	Interleukin-1. (262 aa)
	G3P926_GASAC	Zinc finger protein 750. (589 aa)
	G3PRB8_GASAC	LLGL scribble cell polarity complex component 2. (1015 aa)
	G3NFT7_GASAC	Upstream transcription factor family member 3. (2079 aa)
	G3NI05_GASAC	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (529 aa)
	G3NKW7_GASAC	Ephrin-A1a; Belongs to the ephrin family. (225 aa)
	G3NM95_GASAC	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2528 aa)
	G3NNJ4_GASAC	Pleckstrin homology-like domain, family B, member 1b. (1366 aa)
	G3NQX2_GASAC	Hepsin; Belongs to the peptidase S1 family. (419 aa)
	GREM1	Gremlin 1, DAN family BMP antagonist. (185 aa)
	G3NT88_GASAC	Protein O-fucosyltransferase 2. (387 aa)
	G3NX28_GASAC	Tripartite motif containing 62, tandem duplicate 1. (475 aa)
	G3NX80_GASAC	Mothers against decapentaplegic homolog. (548 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
	G3NYG6_GASAC	Uncharacterized protein. (303 aa)
	G3P2A5_GASAC	GLI pathogenesis-related 2, like; Belongs to the CRISP family. (156 aa)
	G3P3L9_GASAC	Regulator of cell cycle. (126 aa)
	G3P4T3_GASAC	ALX homeobox 1. (311 aa)
	G3P4W2_GASAC	Uncharacterized protein. (327 aa)
	G3P517_GASAC	Bone morphogenetic protein 16. (424 aa)
	G3P7X5_GASAC	Bone morphogenetic protein 4. (403 aa)
	G3P8R9_GASAC	Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
	G3N5X0_GASAC	Mothers against decapentaplegic homolog. (548 aa)
	G3NA32_GASAC	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (261 aa)
	G3NCM5_GASAC	Pleckstrin homology-like domain, family B, member 2b. (1076 aa)
	G3NDT0_GASAC	Peptidase S72 domain-containing protein. (880 aa)
	G3NFA8_GASAC	Dystroglycan 1. (765 aa)
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (551 aa)
	G3NFQ1_GASAC	Mothers against decapentaplegic homolog. (550 aa)

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G3N5X0_GASAC	G3NA32_GASAC	ENSGACP00000000694	ENSGACP00000002174	Mothers against decapentaplegic homolog.	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	0.652
G3N5X0_GASAC	G3NI05_GASAC	ENSGACP00000000694	ENSGACP00000004965	Mothers against decapentaplegic homolog.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.781
G3N5X0_GASAC	G3NX28_GASAC	ENSGACP00000000694	ENSGACP00000009897	Mothers against decapentaplegic homolog.	Tripartite motif containing 62, tandem duplicate 1.	0.431
G3N5X0_GASAC	G3NX80_GASAC	ENSGACP00000000694	ENSGACP00000009949	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.821
G3N5X0_GASAC	G3P517_GASAC	ENSGACP00000000694	ENSGACP00000012690	Mothers against decapentaplegic homolog.	Bone morphogenetic protein 16.	0.788
G3N5X0_GASAC	G3P7X5_GASAC	ENSGACP00000000694	ENSGACP00000013699	Mothers against decapentaplegic homolog.	Bone morphogenetic protein 4.	0.789
G3N5X0_GASAC	G3P8R9_GASAC	ENSGACP00000000694	ENSGACP00000013993	Mothers against decapentaplegic homolog.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.528
G3N5X0_GASAC	G3PH53_GASAC	ENSGACP00000000694	ENSGACP00000016928	Mothers against decapentaplegic homolog.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.750
G3N5X0_GASAC	G3PI25_GASAC	ENSGACP00000000694	ENSGACP00000017252	Mothers against decapentaplegic homolog.	Goosecoid.	0.433
G3N5X0_GASAC	G3PLV4_GASAC	ENSGACP00000000694	ENSGACP00000018585	Mothers against decapentaplegic homolog.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.535
G3N5X0_GASAC	G3PRQ8_GASAC	ENSGACP00000000694	ENSGACP00000020294	Mothers against decapentaplegic homolog.	Eph receptor A4b.	0.409
G3N5X0_GASAC	G3PXS7_GASAC	ENSGACP00000000694	ENSGACP00000022416	Mothers against decapentaplegic homolog.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.535
G3N5X0_GASAC	G3PZN0_GASAC	ENSGACP00000000694	ENSGACP00000023070	Mothers against decapentaplegic homolog.	Lymphoid enhancer-binding factor 1.	0.920
G3N5X0_GASAC	SMAD4	ENSGACP00000000694	ENSGACP00000022267	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.841
G3N5X0_GASAC	TGFB3	ENSGACP00000000694	ENSGACP00000010043	Mothers against decapentaplegic homolog.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.528
G3N5X0_GASAC	TGFBR2	ENSGACP00000000694	ENSGACP00000004125	Mothers against decapentaplegic homolog.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.781
G3N5X0_GASAC	il1b	ENSGACP00000000694	ENSGACP00000019287	Mothers against decapentaplegic homolog.	Interleukin-1.	0.578
G3NA32_GASAC	G3N5X0_GASAC	ENSGACP00000002174	ENSGACP00000000694	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Mothers against decapentaplegic homolog.	0.652
G3NA32_GASAC	G3NFQ1_GASAC	ENSGACP00000002174	ENSGACP00000004156	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Mothers against decapentaplegic homolog.	0.652
G3NA32_GASAC	G3NI05_GASAC	ENSGACP00000002174	ENSGACP00000004965	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.684