(86 nodes) Glycosaminoglycan metabolic process network (Gasterosteus aculeatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HS3ST2	Sulfotransferase; Belongs to the sulfotransferase 1 family. (364 aa)
	HYAL2	Hyaluronidase. (461 aa)
	HYAL2-2	Hyaluronidase. (466 aa)
	G3N9S1_GASAC	Uncharacterized protein. (925 aa)
	G3N9T1_GASAC	Uncharacterized protein. (586 aa)
	G3NAV9_GASAC	N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. (511 aa)
	SPOCK2	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2. (348 aa)
	G3NCY3_GASAC	Sulfotransferase; Belongs to the sulfotransferase 1 family. (449 aa)
	G3ND18_GASAC	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2a. (901 aa)
	G3NFA7_GASAC	UDP-glucuronate decarboxylase 1. (419 aa)
	G3NG67_GASAC	Hexosyltransferase. (539 aa)
	G3NGA5_GASAC	Sulfotransferase; Belongs to the sulfotransferase 1 family. (364 aa)
	G3NGB7_GASAC	Sulfotransferase; Belongs to the sulfotransferase 1 family. (361 aa)
	EDNRBb	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family. (390 aa)
	G3NKG6_GASAC	Heparan sulfate 2-O-sulfotransferase 1b. (356 aa)
	G3NL52_GASAC	Hexosyltransferase. (764 aa)
	G3NLS5_GASAC	Beta-hexosaminidase. (541 aa)
	G3NLX6_GASAC	Carbohydrate sulfotransferase. (298 aa)
	DSEL	Dermatan sulfate epimerase like a. (1208 aa)
	G3NN30_GASAC	MAM domain containing 2a. (685 aa)
	G3NPS7_GASAC	Uncharacterized protein. (189 aa)
	G3NPY8_GASAC	Hyaluronan synthase 2. (552 aa)
	G3NQD6_GASAC	Neuron-derived neurotrophic factor. (571 aa)
	G3NQN7_GASAC	Hyaluronidase. (393 aa)
	G3NS45_GASAC	Dermatan sulfate epimerase. (947 aa)
	G3NSE8_GASAC	Peptidoglycan recognition protein 6. (277 aa)
	G3NSZ1_GASAC	Hexosyltransferase. (530 aa)
	G3NVG7_GASAC	Hexosyltransferase. (766 aa)
	G3NX78_GASAC	Hyaluronan synthase 1. (575 aa)
	G3NY11_GASAC	Hexosyltransferase. (339 aa)
	EGFLAM	EGF like, fibronectin type III and laminin G domains. (982 aa)
	G3NZ18_GASAC	Carbohydrate sulfotransferase. (420 aa)
	CHST13	Carbohydrate sulfotransferase. (334 aa)
	G3PB96_GASAC	Hexosyltransferase. (307 aa)
	G3PBV3_GASAC	Inter-alpha-trypsin inhibitor heavy chain family member 6. (1197 aa)
	G3PDP1_GASAC	Sulfotransferase; Belongs to the sulfotransferase 1 family. (362 aa)
	G3PDP5_GASAC	PPC domain-containing protein. (148 aa)
	G3PH53_GASAC	Transforming growth factor beta; Belongs to the TGF-beta family. (395 aa)
	G3PH75_GASAC	Iduronidase alpha-L-. (631 aa)
	EDNRBa	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family. (449 aa)
	G3PIW7_GASAC	Xylosyltransferase II. (874 aa)
	G3PJP6_GASAC	Sulfotransferase; Belongs to the sulfotransferase 1 family. (433 aa)
	G3PKY4_GASAC	Sulfotransferase; Belongs to the sulfotransferase 1 family. (447 aa)
	G3PLB6_GASAC	Cell migration inducing hyaluronidase 1. (1327 aa)
	G3PLM7_GASAC	Sulfotransferase; Belongs to the sulfotransferase 1 family. (366 aa)
	G3PLV7_GASAC	Hyaluronan synthase 3. (558 aa)
	G3PLW7_GASAC	Hexosyltransferase. (799 aa)
	il1b	Interleukin-1. (262 aa)
	G3PQ18_GASAC	Uncharacterized protein. (812 aa)
	G3PSK7_GASAC	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (719 aa)
	G3PT03_GASAC	Heparan sulfate 2-O-sulfotransferase 1a. (360 aa)
	G3PTM9_GASAC	Beta-hexosaminidase. (553 aa)
	G3PUR2_GASAC	UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (498 aa)
	G3PV53_GASAC	Hexosyltransferase. (548 aa)
	G3PVH1_GASAC	Xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I). (322 aa)
	G3PWV7_GASAC	Carbohydrate sulfotransferase. (407 aa)
	G3PXM9_GASAC	Glucuronic acid epimerase b. (587 aa)
	G3PXR6_GASAC	CLN6 transmembrane ER protein a. (312 aa)
	G3PYB6_GASAC	Sulfotransferase; Belongs to the sulfotransferase 1 family. (425 aa)
	EDNRA	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (336 aa)
	G3Q1I5_GASAC	Uncharacterized protein. (516 aa)
	G3Q1R3_GASAC	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3. (877 aa)
	G3Q1R7_GASAC	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1a. (886 aa)
	EDNRB2	Endothelin receptor B2; Belongs to the G-protein coupled receptor 1 family. (401 aa)
	G3Q4H4_GASAC	Iduronate 2-sulfatase. (506 aa)
	G3Q5H6_GASAC	N-sulfoglucosamine sulfohydrolase (sulfamidase). (526 aa)
	G3Q660_GASAC	Xylosyltransferase I. (857 aa)
	G3Q6M8_GASAC	Peptidoglycan recognition protein 2. (335 aa)
	G3Q6N9_GASAC	Lysozyme g. (202 aa)
	G3Q6Q1_GASAC	Carbohydrate sulfotransferase. (321 aa)
	G3Q8G5_GASAC	Decorin; May affect the rate of fibrils formation. (358 aa)
	G3Q8I3_GASAC	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (329 aa)
	G3Q9H8_GASAC	N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. (513 aa)
	G3Q9J2_GASAC	Inter-alpha-trypsin inhibitor heavy chain 5. (919 aa)
	G3Q9J4_GASAC	Inter-alpha-trypsin inhibitor heavy chain 2. (966 aa)
	G3P0F9_GASAC	Sulfotransferase; Belongs to the sulfotransferase 1 family. (440 aa)
	G3P187_GASAC	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2. (425 aa)
	G3P1B4_GASAC	Tumor necrosis factor, alpha-induced protein 6. (261 aa)
	G3P1P1_GASAC	Hyaluronidase. (438 aa)
	G3P1P5_GASAC	Hyaluronidase. (480 aa)
	SPAM1	Hyaluronidase. (424 aa)
	G3P4Z3_GASAC	Uncharacterized protein. (863 aa)
	G3P7L4_GASAC	Neuron-derived neurotrophic factor, like. (512 aa)
	G3P8A9_GASAC	Arylsulfatase family, member K. (522 aa)
	G3P975_GASAC	Cell migration inducing hyaluronidase 2. (1395 aa)
	G3P9N8_GASAC	Sulfotransferase; Belongs to the sulfotransferase 1 family. (360 aa)

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHST13	G3NG67_GASAC	ENSGACP00000014335	ENSGACP00000004322	Carbohydrate sulfotransferase.	Hexosyltransferase.	0.730
CHST13	G3NSZ1_GASAC	ENSGACP00000014335	ENSGACP00000008459	Carbohydrate sulfotransferase.	Hexosyltransferase.	0.622
CHST13	G3PB96_GASAC	ENSGACP00000014335	ENSGACP00000014870	Carbohydrate sulfotransferase.	Hexosyltransferase.	0.642
CHST13	G3PKY4_GASAC	ENSGACP00000014335	ENSGACP00000018264	Carbohydrate sulfotransferase.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.655
CHST13	G3PLW7_GASAC	ENSGACP00000014335	ENSGACP00000018598	Carbohydrate sulfotransferase.	Hexosyltransferase.	0.595
CHST13	G3PV53_GASAC	ENSGACP00000014335	ENSGACP00000021490	Carbohydrate sulfotransferase.	Hexosyltransferase.	0.622
CHST13	G3Q6Q1_GASAC	ENSGACP00000014335	ENSGACP00000025561	Carbohydrate sulfotransferase.	Carbohydrate sulfotransferase.	0.843
CHST13	G3Q8G5_GASAC	ENSGACP00000014335	ENSGACP00000026179	Carbohydrate sulfotransferase.	Decorin; May affect the rate of fibrils formation.	0.534
CHST13	G3Q8I3_GASAC	ENSGACP00000014335	ENSGACP00000026197	Carbohydrate sulfotransferase.	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family.	0.585
DSEL	G3PKY4_GASAC	ENSGACP00000006430	ENSGACP00000018264	Dermatan sulfate epimerase like a.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.475
DSEL	G3Q8G5_GASAC	ENSGACP00000006430	ENSGACP00000026179	Dermatan sulfate epimerase like a.	Decorin; May affect the rate of fibrils formation.	0.415
EDNRA	EDNRB2	ENSGACP00000022740	ENSGACP00000024566	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor B2; Belongs to the G-protein coupled receptor 1 family.	0.896
EDNRA	EDNRBa	ENSGACP00000022740	ENSGACP00000017059	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.	0.861
EDNRA	EDNRBb	ENSGACP00000022740	ENSGACP00000005316	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	0.861
EDNRB2	EDNRA	ENSGACP00000024566	ENSGACP00000022740	Endothelin receptor B2; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.896
EDNRB2	EDNRBa	ENSGACP00000024566	ENSGACP00000017059	Endothelin receptor B2; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.	0.841
EDNRB2	EDNRBb	ENSGACP00000024566	ENSGACP00000005316	Endothelin receptor B2; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	0.842
EDNRBa	EDNRA	ENSGACP00000017059	ENSGACP00000022740	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.861
EDNRBa	EDNRB2	ENSGACP00000017059	ENSGACP00000024566	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor B2; Belongs to the G-protein coupled receptor 1 family.	0.841
EDNRBb	EDNRA	ENSGACP00000005316	ENSGACP00000022740	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.861