(75 nodes) BMP signaling pathway network (Gasterosteus aculeatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3PLV4_GASAC	Transforming growth factor beta; Belongs to the TGF-beta family. (436 aa)
	G3PKW5_GASAC	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (997 aa)
	TBX2	T-box transcription factor 2. (684 aa)
	G3PJ39_GASAC	Mothers against decapentaplegic homolog. (467 aa)
	G3PIW4_GASAC	Bone morphogenetic protein 10. (430 aa)
	G3PIS6_GASAC	Repulsive guidance molecule BMP co-receptor a. (425 aa)
	G3PHD8_GASAC	RGM domain family, member D. (412 aa)
	G3PG99_GASAC	Peptidylprolyl isomerase. (401 aa)
	G3PFY2_GASAC	Bone morphogenetic protein 2b. (422 aa)
	G3PEN8_GASAC	Yes-associated protein 1. (443 aa)
	G3PCL4_GASAC	Spartin b. (656 aa)
	G3PCE9_GASAC	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (528 aa)
	G3PB99_GASAC	Uncharacterized protein. (204 aa)
	G3P9K2_GASAC	Peptidylprolyl isomerase. (456 aa)
	G3P8R9_GASAC	Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
	G3P7X5_GASAC	Bone morphogenetic protein 4. (403 aa)
	G3P6K3_GASAC	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
	BMP7	Bone morphogenetic protein 7. (429 aa)
	G3P5L8_GASAC	Repulsive guidance molecule BMP co-receptor b. (434 aa)
	G3P517_GASAC	Bone morphogenetic protein 16. (424 aa)
	G3P2R9_GASAC	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (470 aa)
	G3P0W2_GASAC	Southpaw. (371 aa)
	G3P039_GASAC	Muscle segment homeobox 1a. (299 aa)
	G3NYG6_GASAC	Uncharacterized protein. (303 aa)
	G3NYC1_GASAC	Inositol polyphosphate phosphatase-like 1a. (1228 aa)
	G3NY88_GASAC	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (537 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
	G3NX80_GASAC	Mothers against decapentaplegic homolog. (548 aa)
	G3NVG8_GASAC	Solute carrier family 33 member 1. (525 aa)
	G3NUE6_GASAC	Muscle segment homeobox 3. (263 aa)
	G3NSG3_GASAC	Bone morphogenetic protein 5. (354 aa)
	G3NQR1_GASAC	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (508 aa)
	SMAD3	Mothers against decapentaplegic homolog. (426 aa)
	SMAD6	Mothers against decapentaplegic homolog. (491 aa)
	G3NLI4_GASAC	Left-right determination factor. (362 aa)
	G3NFQ1_GASAC	Mothers against decapentaplegic homolog. (550 aa)
	G3NFP2_GASAC	RGM_C domain-containing protein. (156 aa)
	G3NEK8_GASAC	Ventral homeobox. (253 aa)
	G3NCL0_GASAC	Human immunodeficiency virus type I enhancer binding protein 1. (2626 aa)
	G3NCI8_GASAC	Nodal-related 2. (388 aa)
	G3NCF0_GASAC	Bone morphogenetic protein 6. (436 aa)
	G3NCC1_GASAC	Sphingomyelin phosphodiesterase 3, neutral. (646 aa)
	G3NBR8_GASAC	Growth differentiation factor 3. (376 aa)
	G3NBE1_GASAC	Ubiquitin specific peptidase 9; Belongs to the peptidase C19 family. (2552 aa)
	G3NB85_GASAC	Bone morphogenetic protein 8a. (411 aa)
	G3NA62_GASAC	BMP binding endothelial regulator. (609 aa)
	G3N8R6_GASAC	Sclerostin domain containing 1b. (207 aa)
	G3N5X0_GASAC	Mothers against decapentaplegic homolog. (548 aa)
	G3N513_GASAC	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1069 aa)
	G3QBB9_GASAC	Mothers against decapentaplegic homolog. (455 aa)
	SMAD4	Mothers against decapentaplegic homolog. (526 aa)
	G3PXS7_GASAC	Transforming growth factor beta; Belongs to the TGF-beta family. (418 aa)
	G3PYR3_GASAC	Mothers against decapentaplegic homolog. (470 aa)
	G3PZN0_GASAC	Lymphoid enhancer-binding factor 1. (364 aa)
	G3Q075_GASAC	Programmed cell death 4a. (468 aa)
	G3Q0L4_GASAC	Nodal-related 1. (361 aa)
	G3Q0Z7_GASAC	Mothers against decapentaplegic homolog. (376 aa)
	G3Q217_GASAC	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (443 aa)
	G3Q4B7_GASAC	Programmed cell death 4b. (473 aa)
	G3Q4E5_GASAC	Mothers against decapentaplegic homolog. (472 aa)
	G3Q4I7_GASAC	Bone morphogenetic protein 15. (305 aa)
	G3Q7N9_GASAC	Uncharacterized protein. (218 aa)
	G3Q7P0_GASAC	Uncharacterized protein. (278 aa)
	G3PXF2_GASAC	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
	G3QAB6_GASAC	T-box transcription factor 2a. (605 aa)
	G3PXC2_GASAC	Bone morphogenetic protein 10, like. (429 aa)
	G3PXF6_GASAC	Mothers against decapentaplegic homolog. (518 aa)
	G3PXG0_GASAC	Mothers against decapentaplegic homolog. (420 aa)
	G3PXA7_GASAC	Secreted frizzled-related protein 2. (295 aa)
	G3PWY5_GASAC	FAM83 domain-containing protein. (415 aa)
	G3PWQ8_GASAC	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
	G3PW12_GASAC	Mothers against decapentaplegic homolog. (376 aa)
	G3PS96_GASAC	Uncharacterized protein. (229 aa)
	G3PQR5_GASAC	Bone morphogenetic protein 7b. (427 aa)
	G3PQL1_GASAC	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (522 aa)

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP7	G3N513_GASAC	ENSGACP00000013161	ENSGACP00000000383	Bone morphogenetic protein 7.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.903
BMP7	G3N5X0_GASAC	ENSGACP00000013161	ENSGACP00000000694	Bone morphogenetic protein 7.	Mothers against decapentaplegic homolog.	0.501
BMP7	G3NA62_GASAC	ENSGACP00000013161	ENSGACP00000002205	Bone morphogenetic protein 7.	BMP binding endothelial regulator.	0.565
BMP7	G3NCF0_GASAC	ENSGACP00000013161	ENSGACP00000002999	Bone morphogenetic protein 7.	Bone morphogenetic protein 6.	0.789
BMP7	G3NFQ1_GASAC	ENSGACP00000013161	ENSGACP00000004156	Bone morphogenetic protein 7.	Mothers against decapentaplegic homolog.	0.501
BMP7	G3NQR1_GASAC	ENSGACP00000013161	ENSGACP00000007677	Bone morphogenetic protein 7.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.917
BMP7	G3NSG3_GASAC	ENSGACP00000013161	ENSGACP00000008281	Bone morphogenetic protein 7.	Bone morphogenetic protein 5.	0.808
BMP7	G3NX80_GASAC	ENSGACP00000013161	ENSGACP00000009949	Bone morphogenetic protein 7.	Mothers against decapentaplegic homolog.	0.504
BMP7	G3NY88_GASAC	ENSGACP00000013161	ENSGACP00000010308	Bone morphogenetic protein 7.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.930
BMP7	G3P2R9_GASAC	ENSGACP00000013161	ENSGACP00000011892	Bone morphogenetic protein 7.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.916
BMP7	G3P517_GASAC	ENSGACP00000013161	ENSGACP00000012690	Bone morphogenetic protein 7.	Bone morphogenetic protein 16.	0.790
BMP7	G3P6K3_GASAC	ENSGACP00000013161	ENSGACP00000013226	Bone morphogenetic protein 7.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.917
BMP7	G3P7X5_GASAC	ENSGACP00000013161	ENSGACP00000013699	Bone morphogenetic protein 7.	Bone morphogenetic protein 4.	0.794
BMP7	G3PCE9_GASAC	ENSGACP00000013161	ENSGACP00000015273	Bone morphogenetic protein 7.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.917
BMP7	G3PFY2_GASAC	ENSGACP00000013161	ENSGACP00000016506	Bone morphogenetic protein 7.	Bone morphogenetic protein 2b.	0.807
BMP7	G3PHD8_GASAC	ENSGACP00000013161	ENSGACP00000017013	Bone morphogenetic protein 7.	RGM domain family, member D.	0.421
BMP7	G3PIW4_GASAC	ENSGACP00000013161	ENSGACP00000017543	Bone morphogenetic protein 7.	Bone morphogenetic protein 10.	0.485
BMP7	G3PJ39_GASAC	ENSGACP00000013161	ENSGACP00000017618	Bone morphogenetic protein 7.	Mothers against decapentaplegic homolog.	0.469
BMP7	G3PKW5_GASAC	ENSGACP00000013161	ENSGACP00000018245	Bone morphogenetic protein 7.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.903
BMP7	G3PQL1_GASAC	ENSGACP00000013161	ENSGACP00000019896	Bone morphogenetic protein 7.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.935