(37 nodes) Negative regulation of BMP signaling pathway network (Gasterosteus aculeatus)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	SMURF1	E3 ubiquitin-protein ligase. (729 aa)
	G3NZZ8_GASAC	Noggin; Belongs to the noggin family. (215 aa)
	SMURF2	E3 ubiquitin-protein ligase. (757 aa)
	G3Q344_GASAC	HtrA serine peptidase 3a. (374 aa)
	G3Q6G7_GASAC	LEM domain containing 3. (821 aa)
	G3Q764_GASAC	DAN domain family, member 5. (253 aa)
	G3QBB5_GASAC	Spartin a. (651 aa)
	G3QBV4_GASAC	Chordin-like 2. (450 aa)
	G3PXH4_GASAC	SKI family transcriptional corepressor 1. (781 aa)
	G3P0D9_GASAC	FCP1 homology domain-containing protein. (252 aa)
	G3P1B4_GASAC	Tumor necrosis factor, alpha-induced protein 6. (261 aa)
	G3P399_GASAC	Dickkopf WNT signaling pathway inhibitor 1a. (255 aa)
	G3P6X1_GASAC	Gremlin 2, DAN family BMP antagonist a. (175 aa)
	G3PCL4_GASAC	Spartin b. (656 aa)
	G3PHW0_GASAC	Follistatin-like 3 (secreted glycoprotein). (250 aa)
	G3PHX7_GASAC	V-ski avian sarcoma viral oncogene homolog a. (694 aa)
	G3PN23_GASAC	Noggin; Belongs to the noggin family. (222 aa)
	CTDSPL2	CTD small phosphatase like 2. (471 aa)
	G3PW12_GASAC	Mothers against decapentaplegic homolog. (376 aa)
	G3PXA7_GASAC	Secreted frizzled-related protein 2. (295 aa)
	G3PXF6_GASAC	Mothers against decapentaplegic homolog. (518 aa)
	G3NF85_GASAC	Von Willebrand factor C domain containing 2. (144 aa)
	G3NA32_GASAC	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (261 aa)
	G3NA62_GASAC	BMP binding endothelial regulator. (609 aa)
	NBL1	NBL1, DAN family BMP antagonist. (186 aa)
	G3N8E8_GASAC	V-ski avian sarcoma viral oncogene homolog b. (682 aa)
	G3N8R6_GASAC	Sclerostin domain containing 1b. (207 aa)
	G3Q101_GASAC	SKI family transcriptional corepressor 2. (760 aa)
	G3PXS8_GASAC	SKI-like proto-oncogene a. (694 aa)
	SMAD6	Mothers against decapentaplegic homolog. (491 aa)
	G3NNB5_GASAC	SKI family transcriptional corepressor 1b. (781 aa)
	G3NNS1_GASAC	Sortilin-related receptor, L(DLR class) A repeats containing. (1031 aa)
	GREM1	Gremlin 1, DAN family BMP antagonist. (185 aa)
	G3NSL8_GASAC	FCP1 homology domain-containing protein. (474 aa)
	G3NTB5_GASAC	Von Willebrand factor C domain containing 2 like. (221 aa)
	G3NVD5_GASAC	E3 ubiquitin-protein ligase. (743 aa)
	G3NYG6_GASAC	Uncharacterized protein. (303 aa)

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G3N8E8_GASAC	G3PW12_GASAC	ENSGACP00000001583	ENSGACP00000021801	V-ski avian sarcoma viral oncogene homolog b.	Mothers against decapentaplegic homolog.	0.656
G3N8E8_GASAC	G3PXF6_GASAC	ENSGACP00000001583	ENSGACP00000022295	V-ski avian sarcoma viral oncogene homolog b.	Mothers against decapentaplegic homolog.	0.656
G3N8E8_GASAC	SMAD6	ENSGACP00000001583	ENSGACP00000006716	V-ski avian sarcoma viral oncogene homolog b.	Mothers against decapentaplegic homolog.	0.656
G3N8E8_GASAC	SMURF2	ENSGACP00000001583	ENSGACP00000024100	V-ski avian sarcoma viral oncogene homolog b.	E3 ubiquitin-protein ligase.	0.410
G3NA32_GASAC	G3NNS1_GASAC	ENSGACP00000002174	ENSGACP00000006985	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Sortilin-related receptor, L(DLR class) A repeats containing.	0.555
G3NA32_GASAC	G3NYG6_GASAC	ENSGACP00000002174	ENSGACP00000010386	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Uncharacterized protein.	0.611
G3NA32_GASAC	G3PW12_GASAC	ENSGACP00000002174	ENSGACP00000021801	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Mothers against decapentaplegic homolog.	0.796
G3NA32_GASAC	G3PXA7_GASAC	ENSGACP00000002174	ENSGACP00000022246	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Secreted frizzled-related protein 2.	0.624
G3NA32_GASAC	G3PXF6_GASAC	ENSGACP00000002174	ENSGACP00000022295	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Mothers against decapentaplegic homolog.	0.806
G3NA32_GASAC	SMAD6	ENSGACP00000002174	ENSGACP00000006716	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Mothers against decapentaplegic homolog.	0.801
G3NA62_GASAC	G3PXA7_GASAC	ENSGACP00000002205	ENSGACP00000022246	BMP binding endothelial regulator.	Secreted frizzled-related protein 2.	0.410
G3NA62_GASAC	G3QBV4_GASAC	ENSGACP00000002205	ENSGACP00000027370	BMP binding endothelial regulator.	Chordin-like 2.	0.448
G3NNB5_GASAC	SMAD6	ENSGACP00000006829	ENSGACP00000006716	SKI family transcriptional corepressor 1b.	Mothers against decapentaplegic homolog.	0.449
G3NNS1_GASAC	G3NA32_GASAC	ENSGACP00000006985	ENSGACP00000002174	Sortilin-related receptor, L(DLR class) A repeats containing.	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	0.555
G3NNS1_GASAC	G3NYG6_GASAC	ENSGACP00000006985	ENSGACP00000010386	Sortilin-related receptor, L(DLR class) A repeats containing.	Uncharacterized protein.	0.487
G3NNS1_GASAC	G3PXA7_GASAC	ENSGACP00000006985	ENSGACP00000022246	Sortilin-related receptor, L(DLR class) A repeats containing.	Secreted frizzled-related protein 2.	0.500
G3NVD5_GASAC	G3PHX7_GASAC	ENSGACP00000009304	ENSGACP00000017203	E3 ubiquitin-protein ligase.	V-ski avian sarcoma viral oncogene homolog a.	0.474
G3NVD5_GASAC	G3PW12_GASAC	ENSGACP00000009304	ENSGACP00000021801	E3 ubiquitin-protein ligase.	Mothers against decapentaplegic homolog.	0.953
G3NVD5_GASAC	G3PXF6_GASAC	ENSGACP00000009304	ENSGACP00000022295	E3 ubiquitin-protein ligase.	Mothers against decapentaplegic homolog.	0.902
G3NVD5_GASAC	G3PXS8_GASAC	ENSGACP00000009304	ENSGACP00000022417	E3 ubiquitin-protein ligase.	SKI-like proto-oncogene a.	0.481