(29 nodes) Positive regulation of myeloid cell differentiation network (Gasterosteus aculeatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3QAM1_GASAC	Retinoblastoma 1. (911 aa)
	G3NEH6_GASAC	Colony stimulating factor 1b (macrophage). (270 aa)
	G3NI48_GASAC	Zgc:91849. (983 aa)
	G3NI52_GASAC	Inositol polyphosphate-5-phosphatase D. (868 aa)
	G3NI55_GASAC	Uncharacterized protein. (71 aa)
	casp10	Uncharacterized protein; Belongs to the peptidase C14A family. (472 aa)
	G3NKJ4_GASAC	HCLS1 associated protein X-1. (312 aa)
	G3NLA8_GASAC	Transmembrane protein 64. (186 aa)
	DCSTAMP	Dendrocyte expressed seven transmembrane protein. (470 aa)
	G3NRM9_GASAC	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1635 aa)
	G3NSZ5_GASAC	Family with sequence similarity 210 member B. (158 aa)
	G3NU88_GASAC	MPL proto-oncogene, thrombopoietin receptor. (650 aa)
	G3NUD1_GASAC	Ankyrin repeat domain 54. (329 aa)
	G3NWG7_GASAC	Catenin, beta interacting protein 1. (81 aa)
	G3P0R8_GASAC	Maturin, neural progenitor differentiation regulator homolog (Xenopus). (129 aa)
	G3P7C0_GASAC	GATA binding protein 1a. (428 aa)
	G3PD99_GASAC	Osteoclast stimulatory transmembrane protein. (446 aa)
	G3PH53_GASAC	Transforming growth factor beta; Belongs to the TGF-beta family. (395 aa)
	casp8	Uncharacterized protein; Belongs to the peptidase C14A family. (482 aa)
	G3PLU1_GASAC	Apoptotic chromatin condensation inducer 1a. (1194 aa)
	G3PLY4_GASAC	Tescalcin a. (220 aa)
	G3PN13_GASAC	Uncharacterized protein. (192 aa)
	G3PX50_GASAC	Uncharacterized protein. (169 aa)
	G3PXP4_GASAC	Tescalcin b. (123 aa)
	G3PZN0_GASAC	Lymphoid enhancer-binding factor 1. (364 aa)
	IL12B-3	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (357 aa)
	G3Q668_GASAC	Uncharacterized protein. (260 aa)
	G3N5D6_GASAC	Interleukin 19 like. (171 aa)
	G3NBL1_GASAC	PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1. (207 aa)

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCSTAMP	G3PD99_GASAC	ENSGACP00000006362	ENSGACP00000015573	Dendrocyte expressed seven transmembrane protein.	Osteoclast stimulatory transmembrane protein.	0.528
G3NEH6_GASAC	G3PH53_GASAC	ENSGACP00000003727	ENSGACP00000016928	Colony stimulating factor 1b (macrophage).	Transforming growth factor beta; Belongs to the TGF-beta family.	0.421
G3NEH6_GASAC	G3PN13_GASAC	ENSGACP00000003727	ENSGACP00000018996	Colony stimulating factor 1b (macrophage).	Uncharacterized protein.	0.422
G3NRM9_GASAC	G3P7C0_GASAC	ENSGACP00000007996	ENSGACP00000013494	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	GATA binding protein 1a.	0.535
G3NU88_GASAC	G3PN13_GASAC	ENSGACP00000008906	ENSGACP00000018996	MPL proto-oncogene, thrombopoietin receptor.	Uncharacterized protein.	0.417
G3NU88_GASAC	IL12B-3	ENSGACP00000008906	ENSGACP00000024396	MPL proto-oncogene, thrombopoietin receptor.	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily.	0.506
G3NUD1_GASAC	casp10	ENSGACP00000008949	ENSGACP00000005791	Ankyrin repeat domain 54.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.473
G3NUD1_GASAC	casp8	ENSGACP00000008949	ENSGACP00000016969	Ankyrin repeat domain 54.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.421
G3P7C0_GASAC	G3NRM9_GASAC	ENSGACP00000013494	ENSGACP00000007996	GATA binding protein 1a.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.535
G3PD99_GASAC	DCSTAMP	ENSGACP00000015573	ENSGACP00000006362	Osteoclast stimulatory transmembrane protein.	Dendrocyte expressed seven transmembrane protein.	0.528
G3PH53_GASAC	G3NEH6_GASAC	ENSGACP00000016928	ENSGACP00000003727	Transforming growth factor beta; Belongs to the TGF-beta family.	Colony stimulating factor 1b (macrophage).	0.421
G3PH53_GASAC	G3PN13_GASAC	ENSGACP00000016928	ENSGACP00000018996	Transforming growth factor beta; Belongs to the TGF-beta family.	Uncharacterized protein.	0.401
G3PLU1_GASAC	casp10	ENSGACP00000018572	ENSGACP00000005791	Apoptotic chromatin condensation inducer 1a.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.478
G3PLU1_GASAC	casp8	ENSGACP00000018572	ENSGACP00000016969	Apoptotic chromatin condensation inducer 1a.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.478
G3PN13_GASAC	G3NEH6_GASAC	ENSGACP00000018996	ENSGACP00000003727	Uncharacterized protein.	Colony stimulating factor 1b (macrophage).	0.422
G3PN13_GASAC	G3NU88_GASAC	ENSGACP00000018996	ENSGACP00000008906	Uncharacterized protein.	MPL proto-oncogene, thrombopoietin receptor.	0.417
G3PN13_GASAC	G3PH53_GASAC	ENSGACP00000018996	ENSGACP00000016928	Uncharacterized protein.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.401
G3PN13_GASAC	casp10	ENSGACP00000018996	ENSGACP00000005791	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.987
G3PN13_GASAC	casp8	ENSGACP00000018996	ENSGACP00000016969	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.989
G3Q668_GASAC	casp10	ENSGACP00000025376	ENSGACP00000005791	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.478