(85 nodes) Negative regulation of developmental growth network (Gasterosteus aculeatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3N3Z9_GASAC	Si:dkey-49n23.1; Belongs to the semaphorin family. (687 aa)
	G3N4A8_GASAC	Eph receptor A4, like. (986 aa)
	G3N5B3_GASAC	Uncharacterized protein. (333 aa)
	G3N5T1_GASAC	SCP domain-containing protein; Belongs to the CRISP family. (227 aa)
	G3N5U8_GASAC	Growth differentiation factor 11. (389 aa)
	socs2	Suppressor of cytokine signaling 2. (195 aa)
	G3N6E8_GASAC	Disco-interacting protein 2 homolog Bb. (1576 aa)
	G3N6U0_GASAC	Si:ch73-40a2.1. (883 aa)
	G3N770_GASAC	Uncharacterized protein. (204 aa)
	G3N8N7_GASAC	Sema domain-containing protein; Belongs to the semaphorin family. (642 aa)
	G3NAE3_GASAC	Si:ch211-113g11.6; Belongs to the semaphorin family. (647 aa)
	G3NAP8_GASAC	Uncharacterized protein. (110 aa)
	G3NB82_GASAC	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (437 aa)
	G3ND69_GASAC	Insulin-like growth factor binding protein 2b. (104 aa)
	G3NDU4_GASAC	Sema domain-containing protein. (1044 aa)
	G3NGW7_GASAC	Uncharacterized protein; Belongs to the semaphorin family. (813 aa)
	G3NHE6_GASAC	Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily. (420 aa)
	G3NHR3_GASAC	Receptor like tyrosine kinase. (560 aa)
	G3NI00_GASAC	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (333 aa)
	G3NLG6_GASAC	Semaphorin 7A; Belongs to the semaphorin family. (632 aa)
	G3NQA9_GASAC	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3H; Belongs to the semaphorin family. (746 aa)
	G3NQR8_GASAC	Interferon-related developmental regulator 2. (436 aa)
	G3NQX1_GASAC	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B; Belongs to the semaphorin family. (727 aa)
	G3NR19_GASAC	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl; Belongs to the semaphorin family. (755 aa)
	G3NS78_GASAC	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (618 aa)
	G3NS94_GASAC	Uncharacterized protein. (387 aa)
	SEMA6A	Semaphorin 6A; Belongs to the semaphorin family. (417 aa)
	G3NSG2_GASAC	Disco-interacting protein 2 homolog A. (1587 aa)
	G3NTN0_GASAC	Adrenoceptor beta 1. (378 aa)
	G3NWL9_GASAC	Vestigial-like family member 4b. (295 aa)
	G3NZ63_GASAC	Uncharacterized protein; Belongs to the semaphorin family. (850 aa)
	G3P0M3_GASAC	Disco-interacting protein 2 homolog Ba. (1579 aa)
	G3P1I5_GASAC	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (847 aa)
	G3P301_GASAC	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (579 aa)
	G3P4D2_GASAC	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily. (440 aa)
	G3P618_GASAC	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D; Belongs to the semaphorin family. (810 aa)
	G3P6R5_GASAC	Dual specificity phosphatase 10. (464 aa)
	G3P8Z3_GASAC	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family. (819 aa)
	G3P9P0_GASAC	Sema domain-containing protein; Belongs to the semaphorin family. (794 aa)
	G3PA22_GASAC	Uncharacterized protein. (306 aa)
	G3PAF8_GASAC	Adrenoceptor beta 3a; Belongs to the G-protein coupled receptor 1 family. (354 aa)
	G3PCL4_GASAC	Spartin b. (656 aa)
	G3PDL9_GASAC	Salvador family WW domain containing protein 1. (394 aa)
	G3PE40_GASAC	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family. (749 aa)
	G3PET7_GASAC	Legumain. (436 aa)
	G3PF09_GASAC	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ga; Belongs to the semaphorin family. (743 aa)
	G3PF75_GASAC	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb; Belongs to the semaphorin family. (767 aa)
	G3PFB5_GASAC	Unc-51 like autophagy activating kinase 1a. (1035 aa)
	G3PGQ7_GASAC	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E; Belongs to the semaphorin family. (781 aa)
	G3PGR5_GASAC	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab; Belongs to the semaphorin family. (792 aa)
	G3PGT6_GASAC	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D; Belongs to the semaphorin family. (779 aa)
	G3PI55_GASAC	Sema domain-containing protein; Belongs to the semaphorin family. (816 aa)
	G3PJV9_GASAC	Unc-51 like autophagy activating kinase 2. (1037 aa)
	G3PK06_GASAC	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E; Belongs to the semaphorin family. (902 aa)
	G3PLD1_GASAC	Translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae). (578 aa)
	G3PLT6_GASAC	Reticulon 4 receptor. (467 aa)
	G3PMM3_GASAC	Insulin-like growth factor binding protein 2a. (301 aa)
	G3PN18_GASAC	Si:ch211-129c21.1; Belongs to the semaphorin family. (669 aa)
	G3PP74_GASAC	Sema domain-containing protein; Belongs to the semaphorin family. (508 aa)
	G3PPL1_GASAC	Sema domain-containing protein. (1047 aa)
	G3PQX7_GASAC	Vestigial-like family member 4a. (267 aa)
	G3PRI5_GASAC	Semaphorin 4e; Belongs to the semaphorin family. (778 aa)
	G3PRK6_GASAC	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba; Belongs to the semaphorin family. (795 aa)
	G3PRP8_GASAC	Uncharacterized protein. (979 aa)
	G3PS96_GASAC	Uncharacterized protein. (229 aa)
	G3PSY9_GASAC	Placenta associated 8, tandem duplicate 1. (110 aa)
	G3PVX2_GASAC	Sema domain-containing protein; Belongs to the semaphorin family. (824 aa)
	SEMA4D	Semaphorin 4D; Belongs to the semaphorin family. (556 aa)
	G3PXV7_GASAC	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (190 aa)
	G3PXV9_GASAC	Apolipoprotein Da, duplicate 2; Belongs to the calycin superfamily. Lipocalin family. (186 aa)
	G3PXW5_GASAC	Apolipoprotein Da, duplicate 2; Belongs to the calycin superfamily. Lipocalin family. (190 aa)
	G3PZJ6_GASAC	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	G3PZY2_GASAC	AMP-binding domain-containing protein. (320 aa)
	DIP2C	Disco interacting protein 2 homolog C. (858 aa)
	G3Q0F2_GASAC	Unc-51 like autophagy activating kinase 1. (1079 aa)
	G3Q1J9_GASAC	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	G3Q3E6_GASAC	Adrenoceptor beta 2, surface a. (341 aa)
	G3Q559_GASAC	Interferon-related developmental regulator 1. (432 aa)
	G3Q8D1_GASAC	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family. (718 aa)
	G3Q8Q0_GASAC	Sema domain-containing protein; Belongs to the semaphorin family. (443 aa)
	G3Q8Q1_GASAC	Uncharacterized protein. (185 aa)
	G3Q900_GASAC	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; Belongs to the semaphorin family. (726 aa)
	G3QA87_GASAC	Uncharacterized protein. (177 aa)
	G3QBB5_GASAC	Spartin a. (651 aa)
	G3QC99_GASAC	WW and C2 domain containing 1. (972 aa)

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DIP2C	G3PZY2_GASAC	ENSGACP00000023177	ENSGACP00000023172	Disco interacting protein 2 homolog C.	AMP-binding domain-containing protein.	0.931
G3N3Z9_GASAC	G3Q1J9_GASAC	ENSGACP00000000016	ENSGACP00000023747	Si:dkey-49n23.1; Belongs to the semaphorin family.	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	0.518
G3N4A8_GASAC	G3N5U8_GASAC	ENSGACP00000000128	ENSGACP00000000672	Eph receptor A4, like.	Growth differentiation factor 11.	0.426
G3N4A8_GASAC	G3Q1J9_GASAC	ENSGACP00000000128	ENSGACP00000023747	Eph receptor A4, like.	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	0.462
G3N4A8_GASAC	socs2	ENSGACP00000000128	ENSGACP00000000818	Eph receptor A4, like.	Suppressor of cytokine signaling 2.	0.429
G3N5B3_GASAC	G3N770_GASAC	ENSGACP00000000483	ENSGACP00000001146	Uncharacterized protein.	Uncharacterized protein.	0.458
G3N5B3_GASAC	G3N8N7_GASAC	ENSGACP00000000483	ENSGACP00000001673	Uncharacterized protein.	Sema domain-containing protein; Belongs to the semaphorin family.	0.802
G3N5B3_GASAC	G3NB82_GASAC	ENSGACP00000000483	ENSGACP00000002578	Uncharacterized protein.	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.	0.432
G3N5B3_GASAC	G3NHE6_GASAC	ENSGACP00000000483	ENSGACP00000004754	Uncharacterized protein.	Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.	0.432
G3N5B3_GASAC	G3NQA9_GASAC	ENSGACP00000000483	ENSGACP00000007525	Uncharacterized protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3H; Belongs to the semaphorin family.	0.514
G3N5B3_GASAC	G3NQX1_GASAC	ENSGACP00000000483	ENSGACP00000007737	Uncharacterized protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B; Belongs to the semaphorin family.	0.445
G3N5B3_GASAC	G3NR19_GASAC	ENSGACP00000000483	ENSGACP00000007785	Uncharacterized protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl; Belongs to the semaphorin family.	0.458
G3N5B3_GASAC	G3P4D2_GASAC	ENSGACP00000000483	ENSGACP00000012455	Uncharacterized protein.	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.	0.432
G3N5B3_GASAC	G3P9P0_GASAC	ENSGACP00000000483	ENSGACP00000014314	Uncharacterized protein.	Sema domain-containing protein; Belongs to the semaphorin family.	0.456
G3N5B3_GASAC	G3PF09_GASAC	ENSGACP00000000483	ENSGACP00000016183	Uncharacterized protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ga; Belongs to the semaphorin family.	0.503
G3N5B3_GASAC	G3PF75_GASAC	ENSGACP00000000483	ENSGACP00000016249	Uncharacterized protein.	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb; Belongs to the semaphorin family.	0.422
G3N5B3_GASAC	G3PGQ7_GASAC	ENSGACP00000000483	ENSGACP00000016782	Uncharacterized protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E; Belongs to the semaphorin family.	0.434
G3N5B3_GASAC	G3PGT6_GASAC	ENSGACP00000000483	ENSGACP00000016811	Uncharacterized protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D; Belongs to the semaphorin family.	0.659
G3N5B3_GASAC	G3PN18_GASAC	ENSGACP00000000483	ENSGACP00000019001	Uncharacterized protein.	Si:ch211-129c21.1; Belongs to the semaphorin family.	0.491
G3N5B3_GASAC	G3PRI5_GASAC	ENSGACP00000000483	ENSGACP00000020221	Uncharacterized protein.	Semaphorin 4e; Belongs to the semaphorin family.	0.682