118 items (Gasterosteus aculeatus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3PK08_GASAC	Peroxisomal biogenesis factor 7. (300 aa)
	FGF6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
	G3PKW5_GASAC	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (997 aa)
	G3PM92_GASAC	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	G3PM99_GASAC	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (193 aa)
	G3PNN9_GASAC	Metabolism of cobalamin associated C. (276 aa)
	G3PNU3_GASAC	FAM20B glycosaminoglycan xylosylkinase. (409 aa)
	G3PNU5_GASAC	Ring finger protein 2. (340 aa)
	G3PQA7_GASAC	LEO1 homolog, Paf1/RNA polymerase II complex component. (664 aa)
	G3PRZ2_GASAC	Ankyrin repeat domain 11. (1469 aa)
	G3PSK7_GASAC	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (719 aa)
	G3PSN2_GASAC	SRY-box transcription factor 6. (813 aa)
	G3PUL6_GASAC	WD repeat domain 19. (1415 aa)
	G3PVN5_GASAC	Heart and neural crest derivatives expressed 2. (247 aa)
	G3PVX4_GASAC	Homeobox protein. (313 aa)
	fgf24	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
	G3PX50_GASAC	Uncharacterized protein. (169 aa)
	G3PXA1_GASAC	Nipped-B protein. (2608 aa)
	G3PXS6_GASAC	Transmembrane protein 119b. (197 aa)
	G3PYK7_GASAC	Mab-21-like 2. (359 aa)
	G3PYR6_GASAC	Hedgehog interacting protein. (703 aa)
	G3PYW3_GASAC	Fuzzy planar cell polarity protein. (367 aa)
	G3PZ58_GASAC	Uncharacterized protein. (1133 aa)
	G3PZS6_GASAC	Med12 domain-containing protein. (2150 aa)
	G3Q1C9_GASAC	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (213 aa)
	G3Q1L0_GASAC	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (746 aa)
	G3Q1P0_GASAC	Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1044 aa)
	G3Q1P9_GASAC	Zinc finger, AN1-type domain 5b. (211 aa)
	G3Q265_GASAC	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (436 aa)
	G3Q341_GASAC	Annexin. (660 aa)
	G3Q3W5_GASAC	RNA polymerase I and III subunit D. (118 aa)
	G3Q4R6_GASAC	Cytochrome P450, family 26, subfamily b, polypeptide 1; Belongs to the cytochrome P450 family. (443 aa)
	G3Q598_GASAC	Polycystic kidney disease 1a. (4283 aa)
	G3Q5R9_GASAC	SRY-box transcription factor 5. (659 aa)
	G3Q7G7_GASAC	RAB33B, member RAS oncogene family a. (220 aa)
	G3Q7Q7_GASAC	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
	G3Q7X1_GASAC	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (371 aa)
	G3Q8N5_GASAC	N-acetylglucosamine-1-phosphate transferase subunits alpha and beta. (1226 aa)
	G3P469_GASAC	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (262 aa)
	G3P464_GASAC	Homeobox C10a. (326 aa)
	G3P3T9_GASAC	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (462 aa)
	OTOR	Otoraplin. (132 aa)
	G3P1Q7_GASAC	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (806 aa)
	G3P1H7_GASAC	WW domain-containing protein. (736 aa)
	G3P0Z4_GASAC	Golgi glycoprotein 1a. (1138 aa)
	G3P0T2_GASAC	RNA binding motif protein 24b. (222 aa)
	G3P0L7_GASAC	Intraflagellar transport 140 homolog (Chlamydomonas). (1373 aa)
	G3P0F3_GASAC	Refilin B. (196 aa)
	G3P039_GASAC	Muscle segment homeobox 1a. (299 aa)
	G3NY23_GASAC	Nipped-B protein. (2557 aa)
	G3NUH9_GASAC	Distal-less homeobox 5a. (285 aa)
	G3NU11_GASAC	Ectodysplasin A receptor. (517 aa)
	G3NTZ4_GASAC	HMG box domain-containing protein. (764 aa)
	G3NTG7_GASAC	IlvB (bacterial acetolactate synthase)-like; Belongs to the TPP enzyme family. (634 aa)
	G3NT19_GASAC	Tsukushi small leucine rich proteoglycan homolog (Xenopus laevis). (365 aa)
	G3NT01_GASAC	Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b; Belongs to the serpin family. (405 aa)
	G3NSJ5_GASAC	RAD21 cohesin complex component a. (636 aa)
	G3NS38_GASAC	RAB23, member RAS oncogene family. (235 aa)
	G3NS36_GASAC	RAP1A, member of RAS oncogene family b. (185 aa)
	G3NQX5_GASAC	Scleraxis bHLH transcription factor a. (209 aa)
	G3NPD0_GASAC	Uncharacterized protein. (1348 aa)
	G3NP48_GASAC	RNA binding motif protein 24a. (220 aa)
	G3NMW1_GASAC	Sp5 transcription factor a. (369 aa)
	G3NMN1_GASAC	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (782 aa)
	G3NMF3_GASAC	Distal-less homeobox 1a. (254 aa)
	G3NME3_GASAC	Distal-less homeobox 2b. (274 aa)
	G3NL69_GASAC	Follistatin a. (345 aa)
	G3NKQ4_GASAC	Dehydrogenase/reductase (SDR family) member 3b; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (311 aa)
	G3NKC7_GASAC	Dispatched homolog 1 (Drosophila). (1024 aa)
	MEF2D	Myocyte enhancer factor 2D. (530 aa)
	G3NJI4_GASAC	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (765 aa)
	G3NJ56_GASAC	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (228 aa)
	G3NIR9_GASAC	WD repeat domain 60. (973 aa)
	G3NIG1_GASAC	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (413 aa)
	G3NI51_GASAC	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
	G3NI05_GASAC	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (529 aa)
	G3NHR3_GASAC	Receptor like tyrosine kinase. (560 aa)
	G3NHA8_GASAC	Cysteine-serine-rich nuclear protein 1b. (378 aa)
	G3NG04_GASAC	Sphingosine-1-phosphate lyase 1. (563 aa)
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (551 aa)
	G3NFL6_GASAC	Fras1 related extracellular matrix 1b. (2166 aa)
	RAD21	RAD21 cohesin complex component. (641 aa)
	G3NES8_GASAC	Cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins. (772 aa)
	G3NDD5_GASAC	Sharpin_PH domain-containing protein. (131 aa)
	G3NDD0_GASAC	Sharpin and rbck1 related. (507 aa)
	G3NCC1_GASAC	Sphingomyelin phosphodiesterase 3, neutral. (646 aa)
	G3N9A1_GASAC	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (159 aa)
	G3N7D6_GASAC	Fras1 related extracellular matrix 1a. (2182 aa)
	G3N651_GASAC	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1630 aa)
	G3N5K2_GASAC	NGFI-A binding protein 2 (EGR1 binding protein 2). (447 aa)
	G3N513_GASAC	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1069 aa)
	G3N3Z9_GASAC	Si:dkey-49n23.1; Belongs to the semaphorin family. (687 aa)
	FGF6-2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	G3Q9J1_GASAC	Uncharacterized protein. (528 aa)
	G3Q9Q7_GASAC	Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a; Belongs to the serpin family. (410 aa)
	G3QBJ3_GASAC	Notchless homolog 1 (Drosophila). (477 aa)
	G3P4T3_GASAC	ALX homeobox 1. (311 aa)
	RING1	Ring finger protein 1. (372 aa)
	G3P633_GASAC	Distal-less homeobox 3b. (291 aa)
	G3P6Z7_GASAC	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (845 aa)
	G3P714_GASAC	Uncharacterized protein. (947 aa)
	G3P730_GASAC	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (379 aa)
	G3P8C2_GASAC	Activated leukocyte cell adhesion molecule b. (596 aa)
	G3PA01_GASAC	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
	G3PAX7_GASAC	Neuroblastoma amplified sequence. (2377 aa)
	TCF15	Transcription factor 15. (202 aa)
	G3PC80_GASAC	Zinc finger, AN1-type domain 5a. (208 aa)
	G3PDC4_GASAC	Transcription factor 15. (179 aa)
	G3PDS2_GASAC	RAP1A, member of RAS oncogene family a. (184 aa)
	G3PF04_GASAC	Thyroid hormone receptor interactor 11. (1989 aa)
	G3PFB3_GASAC	Zgc:77486. (214 aa)
	G3PFG8_GASAC	Refilin A. (238 aa)
	G3PFY2_GASAC	Bone morphogenetic protein 2b. (422 aa)
	G3PGK5_GASAC	Cysteine-serine-rich nuclear protein 1a. (529 aa)
	G3PGT6_GASAC	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D; Belongs to the semaphorin family. (779 aa)
	G3PI38_GASAC	T-box transcription factor 1. (460 aa)
	G3PI50_GASAC	IGFBP N-terminal domain-containing protein. (80 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (847 aa)

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH2	G3NES8_GASAC	ENSGACP00000017426	ENSGACP00000003829	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins.	0.842
CDH2	G3NJ56_GASAC	ENSGACP00000017426	ENSGACP00000005367	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.667
CDH2	MEF2D	ENSGACP00000017426	ENSGACP00000005559	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Myocyte enhancer factor 2D.	0.547
FGF6	G3N9A1_GASAC	ENSGACP00000018239	ENSGACP00000001891	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.449
FGF6	G3NI51_GASAC	ENSGACP00000018239	ENSGACP00000005011	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.498
FGF6	G3PM92_GASAC	ENSGACP00000018239	ENSGACP00000018723	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.565
FGF6	G3PM99_GASAC	ENSGACP00000018239	ENSGACP00000018730	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.448
FGF6	G3Q1C9_GASAC	ENSGACP00000018239	ENSGACP00000023677	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family.	0.527
FGF6	G3Q1P0_GASAC	ENSGACP00000018239	ENSGACP00000023788	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.909
FGF6	G3Q7Q7_GASAC	ENSGACP00000018239	ENSGACP00000025917	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.451
FGF6	fgf24	ENSGACP00000018239	ENSGACP00000022045	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.490
FGF6-2	G3N9A1_GASAC	ENSGACP00000026294	ENSGACP00000001891	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.462
FGF6-2	G3NI51_GASAC	ENSGACP00000026294	ENSGACP00000005011	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.499
FGF6-2	G3PM92_GASAC	ENSGACP00000026294	ENSGACP00000018723	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.569
FGF6-2	G3PM99_GASAC	ENSGACP00000026294	ENSGACP00000018730	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.451
FGF6-2	G3Q1C9_GASAC	ENSGACP00000026294	ENSGACP00000023677	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family.	0.490
FGF6-2	G3Q1P0_GASAC	ENSGACP00000026294	ENSGACP00000023788	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.909
FGF6-2	G3Q7Q7_GASAC	ENSGACP00000026294	ENSGACP00000025917	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.450
FGF6-2	fgf24	ENSGACP00000026294	ENSGACP00000022045	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.490
G3N3Z9_GASAC	G3NFL6_GASAC	ENSGACP00000000016	ENSGACP00000004121	Si:dkey-49n23.1; Belongs to the semaphorin family.	Fras1 related extracellular matrix 1b.	0.422