(43 nodes) Negative regulation of T cell activation network (Gasterosteus aculeatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3N431_GASAC	RIPOR family member 3. (890 aa)
	G3N6V9_GASAC	Si:ch211-157b11.8. (217 aa)
	G3NCJ5_GASAC	Si:dkey-206d17.12. (543 aa)
	G3NGQ7_GASAC	Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (452 aa)
	G3NGY6_GASAC	V-set immunoregulatory receptor. (297 aa)
	G3NI63_GASAC	T-box transcription factor 21. (428 aa)
	G3NJV4_GASAC	Tumor necrosis factor receptor superfamily, member 21. (639 aa)
	G3NLJ5_GASAC	RHO family interacting cell polarization regulator 2. (1077 aa)
	G3NLP4_GASAC	E3 ubiquitin-protein ligase. (864 aa)
	G3NR11_GASAC	E3 ubiquitin-protein ligase. (904 aa)
	G3NV42_GASAC	Glycoprotein (transmembrane) nmb. (556 aa)
	G3P041_GASAC	V-set domain containing T cell activation inhibitor 1. (271 aa)
	G3P222_GASAC	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family. (1948 aa)
	G3P4N2_GASAC	Uncharacterized protein. (219 aa)
	G3P4N3_GASAC	Fibrinogen C-terminal domain-containing protein. (229 aa)
	G3P6Q8_GASAC	H2.0-like homeo box 1 (Drosophila). (365 aa)
	G3P779_GASAC	Si:ch211-203k16.3. (239 aa)
	G3P780_GASAC	Arginase. (355 aa)
	G3PDG4_GASAC	CCAAT enhancer binding protein beta. (284 aa)
	G3QCI8_GASAC	Interferon regulatory factor. (298 aa)
	G3QCF7_GASAC	Leucine rich repeat containing 32. (639 aa)
	G3Q9L2_GASAC	Ig-like domain-containing protein. (202 aa)
	G3Q978_GASAC	PRKC, apoptosis, WT1, regulator. (321 aa)
	G3Q7V8_GASAC	Fibrinogen-like 1. (302 aa)
	G3Q4W3_GASAC	Fibrinogen-like 2a. (424 aa)
	G3Q2V7_GASAC	Uncharacterized protein. (659 aa)
	G3PZB0_GASAC	Ring finger and CCCH-type domains 2. (836 aa)
	G3PZ99_GASAC	Uncharacterized protein. (268 aa)
	G3PZ94_GASAC	NACHT domain-containing protein. (187 aa)
	G3PX51_GASAC	Transmembrane 131 like. (1551 aa)
	G3PW04_GASAC	Mitotic arrest deficient 1 like 1. (716 aa)
	G3PVT8_GASAC	Fibrinogen C-terminal domain-containing protein. (220 aa)
	G3PT94_GASAC	Fibronectin type-III domain-containing protein. (142 aa)
	G3PSV9_GASAC	Glomulin, FKBP associated protein a. (603 aa)
	G3PQZ8_GASAC	Membrane-associated ring finger (C3HC4) 7. (734 aa)
	G3PMW2_GASAC	Suppressor of cytokine signaling 1a. (203 aa)
	G3PLH2_GASAC	Core-binding factor subunit beta. (188 aa)
	G3PL24_GASAC	Zinc finger CCCH-type containing 12A. (578 aa)
	G3PL20_GASAC	Ring finger and CCCH-type domains 1b. (1118 aa)
	G3PKE4_GASAC	Galectin. (337 aa)
	G3PIC5_GASAC	TNFR-Cys domain-containing protein. (156 aa)
	G3PH53_GASAC	Transforming growth factor beta; Belongs to the TGF-beta family. (395 aa)
	G3PFK8_GASAC	Arginase. (349 aa)

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G3N431_GASAC	G3PIC5_GASAC	ENSGACP00000000048	ENSGACP00000017352	RIPOR family member 3.	TNFR-Cys domain-containing protein.	0.409
G3NI63_GASAC	G3P6Q8_GASAC	ENSGACP00000005023	ENSGACP00000013281	T-box transcription factor 21.	H2.0-like homeo box 1 (Drosophila).	0.555
G3NLJ5_GASAC	G3PIC5_GASAC	ENSGACP00000006208	ENSGACP00000017352	RHO family interacting cell polarization regulator 2.	TNFR-Cys domain-containing protein.	0.409
G3NLP4_GASAC	G3P222_GASAC	ENSGACP00000006257	ENSGACP00000011645	E3 ubiquitin-protein ligase.	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	0.498
G3NLP4_GASAC	G3PH53_GASAC	ENSGACP00000006257	ENSGACP00000016928	E3 ubiquitin-protein ligase.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.537
G3NLP4_GASAC	G3PLH2_GASAC	ENSGACP00000006257	ENSGACP00000018453	E3 ubiquitin-protein ligase.	Core-binding factor subunit beta.	0.580
G3NR11_GASAC	G3P222_GASAC	ENSGACP00000007777	ENSGACP00000011645	E3 ubiquitin-protein ligase.	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	0.498
G3NR11_GASAC	G3PH53_GASAC	ENSGACP00000007777	ENSGACP00000016928	E3 ubiquitin-protein ligase.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.537
G3NR11_GASAC	G3PLH2_GASAC	ENSGACP00000007777	ENSGACP00000018453	E3 ubiquitin-protein ligase.	Core-binding factor subunit beta.	0.580
G3P041_GASAC	G3PZ94_GASAC	ENSGACP00000010964	ENSGACP00000022934	V-set domain containing T cell activation inhibitor 1.	NACHT domain-containing protein.	0.536
G3P222_GASAC	G3NLP4_GASAC	ENSGACP00000011645	ENSGACP00000006257	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	E3 ubiquitin-protein ligase.	0.498
G3P222_GASAC	G3NR11_GASAC	ENSGACP00000011645	ENSGACP00000007777	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	E3 ubiquitin-protein ligase.	0.498
G3P222_GASAC	G3Q2V7_GASAC	ENSGACP00000011645	ENSGACP00000024206	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	Uncharacterized protein.	0.401
G3P222_GASAC	G3QCF7_GASAC	ENSGACP00000011645	ENSGACP00000027573	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	Leucine rich repeat containing 32.	0.401
G3P6Q8_GASAC	G3NI63_GASAC	ENSGACP00000013281	ENSGACP00000005023	H2.0-like homeo box 1 (Drosophila).	T-box transcription factor 21.	0.555
G3P780_GASAC	G3PFK8_GASAC	ENSGACP00000013454	ENSGACP00000016382	Arginase.	Arginase.	0.845
G3PDG4_GASAC	G3PLH2_GASAC	ENSGACP00000015638	ENSGACP00000018453	CCAAT enhancer binding protein beta.	Core-binding factor subunit beta.	0.737
G3PDG4_GASAC	G3PZ94_GASAC	ENSGACP00000015638	ENSGACP00000022934	CCAAT enhancer binding protein beta.	NACHT domain-containing protein.	0.460
G3PDG4_GASAC	G3QCI8_GASAC	ENSGACP00000015638	ENSGACP00000027604	CCAAT enhancer binding protein beta.	Interferon regulatory factor.	0.474
G3PFK8_GASAC	G3P780_GASAC	ENSGACP00000016382	ENSGACP00000013454	Arginase.	Arginase.	0.845