73 items (Gasterosteus aculeatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3PDF6_GASAC	Prokineticin 2. (106 aa)
	G3QBY8_GASAC	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (151 aa)
	G3QA55_GASAC	Centromere protein V. (150 aa)
	G3Q9B0_GASAC	Insulin-like growth factor 1. (185 aa)
	G3Q8Z0_GASAC	Pleiotrophin. (202 aa)
	G3NB64_GASAC	GRB2 associated, regulator of MAPK1. (849 aa)
	G3Q7V3_GASAC	Uncharacterized protein. (842 aa)
	G3Q7V1_GASAC	Uncharacterized protein. (166 aa)
	G3Q7Q7_GASAC	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
	G3Q4B9_GASAC	Uncharacterized protein. (193 aa)
	G3Q2R0_GASAC	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
	G3Q2H2_GASAC	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
	SVIL	Supervillin. (2175 aa)
	G3PXW4_GASAC	Vascular endothelial growth factor Bb; Belongs to the PDGF/VEGF growth factor family. (145 aa)
	G3PXS7_GASAC	Transforming growth factor beta; Belongs to the TGF-beta family. (418 aa)
	KIF23	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (944 aa)
	G3PX48_GASAC	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (202 aa)
	G3PWT9_GASAC	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	G3PWA3_GASAC	GIPC PDZ domain containing family, member 2. (329 aa)
	G3PW69_GASAC	Platelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family. (305 aa)
	G3PVJ6_GASAC	Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family. (357 aa)
	G3PVJ4_GASAC	Aurora kinase B; Belongs to the protein kinase superfamily. (331 aa)
	G3PRK4_GASAC	Midkine a. (147 aa)
	G3PQR2_GASAC	Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (309 aa)
	il1b	Interleukin-1. (262 aa)
	G3PNM2_GASAC	TYR_PHOSPHATASE_2 domain-containing protein. (383 aa)
	G3PM99_GASAC	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (193 aa)
	G3PM92_GASAC	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	G3PLV4_GASAC	Transforming growth factor beta; Belongs to the TGF-beta family. (436 aa)
	CUL3	Cullin 3; Belongs to the cullin family. (766 aa)
	G3PLM1_GASAC	Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family. (189 aa)
	G3PJW2_GASAC	Citron rho-interacting serine/threonine kinase b. (1622 aa)
	G3PJS5_GASAC	Cell division cycle 14Ab. (577 aa)
	G3PJA4_GASAC	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (191 aa)
	G3PH53_GASAC	Transforming growth factor beta; Belongs to the TGF-beta family. (395 aa)
	CDC42	Cell division cycle 42. (197 aa)
	G3PF58_GASAC	Chemokine (C-X-C motif) receptor 5; Belongs to the G-protein coupled receptor 1 family. (350 aa)
	G3PBV5_GASAC	Platelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family. (234 aa)
	G3PAT8_GASAC	Insulin-like growth factor 2b. (214 aa)
	G3PA20_GASAC	Uncharacterized protein. (191 aa)
	G3P9I9_GASAC	NK3 homeobox 1. (204 aa)
	G3P8R9_GASAC	Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
	G3P840_GASAC	GIPC PDZ domain containing family, member 1. (337 aa)
	G3P6U5_GASAC	Uncharacterized protein. (191 aa)
	G3P3N5_GASAC	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. (469 aa)
	G3P2I7_GASAC	Integrin beta 1 binding protein 1. (202 aa)
	G3P2A8_GASAC	Kinesin family member 14. (717 aa)
	G3P212_GASAC	GIPC PDZ domain containing family, member 3. (351 aa)
	G3P1D6_GASAC	Citron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2081 aa)
	G3P069_GASAC	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (243 aa)
	G3NZV7_GASAC	Uncharacterized protein. (626 aa)
	G3NZH9_GASAC	Platelet derived growth factor d. (337 aa)
	G3NYV1_GASAC	Prokineticin 1. (108 aa)
	G3NYI4_GASAC	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (150 aa)
	G3NY10_GASAC	CULLIN_2 domain-containing protein; Belongs to the cullin family. (775 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
	G3NX23_GASAC	GRB2 associated, regulator of MAPK1-like. (727 aa)
	G3NUQ4_GASAC	Supervillin d. (1032 aa)
	G3NUB9_GASAC	Cell division cycle 14B. (519 aa)
	G3NP99_GASAC	Polymerase (DNA-directed), delta interacting protein 2. (377 aa)
	G3NNL8_GASAC	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (875 aa)
	HDGF	Heparin binding growth factor. (263 aa)
	G3NGM7_GASAC	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
	G3NG13_GASAC	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (276 aa)
	G3NEN1_GASAC	Uncharacterized protein. (247 aa)
	G3NEM8_GASAC	Uncharacterized protein. (145 aa)
	G3NBR8_GASAC	Growth differentiation factor 3. (376 aa)
	G3NBI9_GASAC	Epithelial cell transforming 2. (974 aa)
	G3N4L2_GASAC	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (156 aa)
	G3N7K3_GASAC	Supervillin a. (1760 aa)
	G3N7P8_GASAC	Cell division cycle 6 homolog (S. cerevisiae). (252 aa)
	G3N8C7_GASAC	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (235 aa)
	G3N9A1_GASAC	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (159 aa)

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	CUL3	ENSGACP00000016487	ENSGACP00000018561	Cell division cycle 42.	Cullin 3; Belongs to the cullin family.	0.557
CDC42	G3NB64_GASAC	ENSGACP00000016487	ENSGACP00000002560	Cell division cycle 42.	GRB2 associated, regulator of MAPK1.	0.493
CDC42	G3NBI9_GASAC	ENSGACP00000016487	ENSGACP00000002686	Cell division cycle 42.	Epithelial cell transforming 2.	0.806
CDC42	G3NX23_GASAC	ENSGACP00000016487	ENSGACP00000009892	Cell division cycle 42.	GRB2 associated, regulator of MAPK1-like.	0.500
CDC42	G3NY10_GASAC	ENSGACP00000016487	ENSGACP00000010230	Cell division cycle 42.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.557
CDC42	G3NZV7_GASAC	ENSGACP00000016487	ENSGACP00000010880	Cell division cycle 42.	Uncharacterized protein.	0.936
CDC42	G3P1D6_GASAC	ENSGACP00000016487	ENSGACP00000011409	Cell division cycle 42.	Citron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.620
CDC42	G3P2A8_GASAC	ENSGACP00000016487	ENSGACP00000011731	Cell division cycle 42.	Kinesin family member 14.	0.458
CDC42	G3P6U5_GASAC	ENSGACP00000016487	ENSGACP00000013319	Cell division cycle 42.	Uncharacterized protein.	0.723
CDC42	G3PJA4_GASAC	ENSGACP00000016487	ENSGACP00000017683	Cell division cycle 42.	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	0.446
CDC42	G3PJW2_GASAC	ENSGACP00000016487	ENSGACP00000017892	Cell division cycle 42.	Citron rho-interacting serine/threonine kinase b.	0.620
CDC42	G3PLM1_GASAC	ENSGACP00000016487	ENSGACP00000018502	Cell division cycle 42.	Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family.	0.628
CDC42	G3Q4B9_GASAC	ENSGACP00000016487	ENSGACP00000024723	Cell division cycle 42.	Uncharacterized protein.	0.723
CUL3	CDC42	ENSGACP00000018561	ENSGACP00000016487	Cullin 3; Belongs to the cullin family.	Cell division cycle 42.	0.557
CUL3	G3N7P8_GASAC	ENSGACP00000018561	ENSGACP00000001331	Cullin 3; Belongs to the cullin family.	Cell division cycle 6 homolog (S. cerevisiae).	0.845
CUL3	G3NP99_GASAC	ENSGACP00000018561	ENSGACP00000007163	Cullin 3; Belongs to the cullin family.	Polymerase (DNA-directed), delta interacting protein 2.	0.508
CUL3	G3P6U5_GASAC	ENSGACP00000018561	ENSGACP00000013319	Cullin 3; Belongs to the cullin family.	Uncharacterized protein.	0.557
CUL3	G3PA20_GASAC	ENSGACP00000018561	ENSGACP00000014444	Cullin 3; Belongs to the cullin family.	Uncharacterized protein.	0.557
CUL3	G3PVJ4_GASAC	ENSGACP00000018561	ENSGACP00000021631	Cullin 3; Belongs to the cullin family.	Aurora kinase B; Belongs to the protein kinase superfamily.	0.777
CUL3	G3Q4B9_GASAC	ENSGACP00000018561	ENSGACP00000024723	Cullin 3; Belongs to the cullin family.	Uncharacterized protein.	0.557