(43 nodes) Artery development network (Gasterosteus aculeatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3PHC9_GASAC	HECT domain containing 1. (2549 aa)
	G3PK26_GASAC	Uncharacterized protein. (239 aa)
	G3PKL7_GASAC	Angiomotin like 2b. (609 aa)
	G3PKW5_GASAC	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (997 aa)
	G3PL07_GASAC	T-cell acute lymphocytic leukemia 1. (352 aa)
	G3PLC5_GASAC	NPR3-like, GATOR1 complex subunit. (604 aa)
	G3PLH6_GASAC	Notch receptor 1b. (2478 aa)
	G3PLM1_GASAC	Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family. (189 aa)
	G3PMS1_GASAC	Dynactin 5. (182 aa)
	G3PUD0_GASAC	Notch receptor 1a. (2434 aa)
	ANGPTL3	Angiopoietin like 3. (480 aa)
	G3PVZ4_GASAC	15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (268 aa)
	G3PW12_GASAC	Mothers against decapentaplegic homolog. (376 aa)
	G3PXF6_GASAC	Mothers against decapentaplegic homolog. (518 aa)
	G3PY58_GASAC	Uncharacterized protein. (637 aa)
	EDNRA	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (336 aa)
	G3Q7E4_GASAC	AT rich interactive domain 2 (ARID, RFX-like). (1687 aa)
	G3Q958_GASAC	MADS-box domain-containing protein. (473 aa)
	G3Q9N6_GASAC	DUF1943 domain-containing protein. (96 aa)
	G3N4P3_GASAC	DUF1943 domain-containing protein. (96 aa)
	G3N513_GASAC	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1069 aa)
	G3N994_GASAC	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (256 aa)
	G3N9A7_GASAC	Zgc:56585; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (268 aa)
	G3NAB8_GASAC	PR domain containing 1a, with ZNF domain. (694 aa)
	G3NCR5_GASAC	Calcitonin receptor-like a; Belongs to the G-protein coupled receptor 2 family. (481 aa)
	G3NE02_GASAC	PR domain containing 1b, with ZNF domain. (706 aa)
	G3NHK0_GASAC	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (320 aa)
	G3NHW6_GASAC	Angiomotin like 2a. (635 aa)
	SRF	Serum response factor. (507 aa)
	G3NMM2_GASAC	Neurofibromin 1b. (2449 aa)
	SMAD6	Mothers against decapentaplegic homolog. (491 aa)
	G3NSP8_GASAC	Peptidylprolyl isomerase. (568 aa)
	G3NTA0_GASAC	Uncharacterized protein. (279 aa)
	G3NV04_GASAC	Angiopoietin-like 3. (471 aa)
	G3P266_GASAC	Peptidylprolyl isomerase. (590 aa)
	G3P415_GASAC	Uncharacterized protein. (677 aa)
	G3P546_GASAC	Apolipoprotein Bb, tandem duplicate 2. (3689 aa)
	G3P560_GASAC	Nerve growth factor receptor a (TNFR superfamily, member 16). (321 aa)
	G3P570_GASAC	Vitellogenin domain-containing protein. (1648 aa)
	G3P573_GASAC	Uncharacterized protein. (445 aa)
	G3P9I9_GASAC	NK3 homeobox 1. (204 aa)
	G3PA67_GASAC	Transcription factor 21. (170 aa)
	G3PCZ2_GASAC	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (336 aa)

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G3N513_GASAC	G3P560_GASAC	ENSGACP00000000383	ENSGACP00000012733	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Nerve growth factor receptor a (TNFR superfamily, member 16).	0.493
G3N513_GASAC	G3PW12_GASAC	ENSGACP00000000383	ENSGACP00000021801	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.699
G3N513_GASAC	G3PXF6_GASAC	ENSGACP00000000383	ENSGACP00000022295	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.699
G3N513_GASAC	SMAD6	ENSGACP00000000383	ENSGACP00000006716	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.699
G3NAB8_GASAC	G3P560_GASAC	ENSGACP00000002263	ENSGACP00000012733	PR domain containing 1a, with ZNF domain.	Nerve growth factor receptor a (TNFR superfamily, member 16).	0.606
G3NE02_GASAC	G3P560_GASAC	ENSGACP00000003553	ENSGACP00000012733	PR domain containing 1b, with ZNF domain.	Nerve growth factor receptor a (TNFR superfamily, member 16).	0.606
G3P415_GASAC	G3P560_GASAC	ENSGACP00000012338	ENSGACP00000012733	Uncharacterized protein.	Nerve growth factor receptor a (TNFR superfamily, member 16).	0.606
G3P560_GASAC	G3N513_GASAC	ENSGACP00000012733	ENSGACP00000000383	Nerve growth factor receptor a (TNFR superfamily, member 16).	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.493
G3P560_GASAC	G3NAB8_GASAC	ENSGACP00000012733	ENSGACP00000002263	Nerve growth factor receptor a (TNFR superfamily, member 16).	PR domain containing 1a, with ZNF domain.	0.606
G3P560_GASAC	G3NE02_GASAC	ENSGACP00000012733	ENSGACP00000003553	Nerve growth factor receptor a (TNFR superfamily, member 16).	PR domain containing 1b, with ZNF domain.	0.606
G3P560_GASAC	G3P415_GASAC	ENSGACP00000012733	ENSGACP00000012338	Nerve growth factor receptor a (TNFR superfamily, member 16).	Uncharacterized protein.	0.606
G3P560_GASAC	G3PKW5_GASAC	ENSGACP00000012733	ENSGACP00000018245	Nerve growth factor receptor a (TNFR superfamily, member 16).	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.493
G3P560_GASAC	G3PLM1_GASAC	ENSGACP00000012733	ENSGACP00000018502	Nerve growth factor receptor a (TNFR superfamily, member 16).	Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family.	0.855
G3P570_GASAC	G3P573_GASAC	ENSGACP00000012743	ENSGACP00000012746	Vitellogenin domain-containing protein.	Uncharacterized protein.	0.932
G3P573_GASAC	G3P570_GASAC	ENSGACP00000012746	ENSGACP00000012743	Uncharacterized protein.	Vitellogenin domain-containing protein.	0.932
G3PK26_GASAC	G3PLH6_GASAC	ENSGACP00000017956	ENSGACP00000018457	Uncharacterized protein.	Notch receptor 1b.	0.567
G3PK26_GASAC	G3PUD0_GASAC	ENSGACP00000017956	ENSGACP00000021217	Uncharacterized protein.	Notch receptor 1a.	0.567
G3PKW5_GASAC	G3P560_GASAC	ENSGACP00000018245	ENSGACP00000012733	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Nerve growth factor receptor a (TNFR superfamily, member 16).	0.493
G3PKW5_GASAC	G3PW12_GASAC	ENSGACP00000018245	ENSGACP00000021801	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.699
G3PKW5_GASAC	G3PXF6_GASAC	ENSGACP00000018245	ENSGACP00000022295	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.699