(19 nodes) Bone cell development network (Gasterosteus aculeatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3PBM5_GASAC	Tyrosine-protein kinase. (537 aa)
	G3PBR8_GASAC	ATPase H+ transporting accessory protein 1b. (435 aa)
	G3PEF6_GASAC	FAM20C golgi associated secretory pathway kinase a. (248 aa)
	G3PEF9_GASAC	FAM20C golgi associated secretory pathway kinase a. (308 aa)
	G3PLW1_GASAC	Leucine-rich repeat kinase 1. (1988 aa)
	G3PVM8_GASAC	Abl-interactor 1b. (485 aa)
	G3PSG6_GASAC	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
	ABI1	Abl-interactor 1a. (504 aa)
	G3NPQ0_GASAC	Glycoprotein Ib platelet subunit beta. (191 aa)
	SRC	Tyrosine-protein kinase. (542 aa)
	G3NRM9_GASAC	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1635 aa)
	G3NSJ6_GASAC	SH2B adaptor protein 3. (585 aa)
	G3NY16_GASAC	E1A binding protein p300 b. (2411 aa)
	G3P6Y8_GASAC	Protein tyrosine phosphatase non-receptor type 6. (582 aa)
	G3Q958_GASAC	MADS-box domain-containing protein. (473 aa)
	G3NM42_GASAC	E1A binding protein p300 a. (2344 aa)
	G3NM14_GASAC	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
	SRF	Serum response factor. (507 aa)
	G3N4N8_GASAC	ATPase H+ transporting accessory protein 1a. (470 aa)

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABI1	G3PBM5_GASAC	ENSGACP00000006752	ENSGACP00000014999	Abl-interactor 1a.	Tyrosine-protein kinase.	0.587
ABI1	SRC	ENSGACP00000006752	ENSGACP00000007343	Abl-interactor 1a.	Tyrosine-protein kinase.	0.587
G3NM14_GASAC	G3PBM5_GASAC	ENSGACP00000006377	ENSGACP00000014999	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein kinase.	0.697
G3NM14_GASAC	SRC	ENSGACP00000006377	ENSGACP00000007343	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein kinase.	0.697
G3NM42_GASAC	G3NRM9_GASAC	ENSGACP00000006405	ENSGACP00000007996	E1A binding protein p300 a.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.741
G3NPQ0_GASAC	G3PBM5_GASAC	ENSGACP00000007314	ENSGACP00000014999	Glycoprotein Ib platelet subunit beta.	Tyrosine-protein kinase.	0.699
G3NPQ0_GASAC	SRC	ENSGACP00000007314	ENSGACP00000007343	Glycoprotein Ib platelet subunit beta.	Tyrosine-protein kinase.	0.703
G3NRM9_GASAC	G3NM42_GASAC	ENSGACP00000007996	ENSGACP00000006405	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	E1A binding protein p300 a.	0.741
G3NRM9_GASAC	G3NY16_GASAC	ENSGACP00000007996	ENSGACP00000010236	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	E1A binding protein p300 b.	0.739
G3NRM9_GASAC	G3PBM5_GASAC	ENSGACP00000007996	ENSGACP00000014999	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Tyrosine-protein kinase.	0.662
G3NRM9_GASAC	SRC	ENSGACP00000007996	ENSGACP00000007343	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Tyrosine-protein kinase.	0.662
G3NSJ6_GASAC	G3PBM5_GASAC	ENSGACP00000008314	ENSGACP00000014999	SH2B adaptor protein 3.	Tyrosine-protein kinase.	0.631
G3NSJ6_GASAC	SRC	ENSGACP00000008314	ENSGACP00000007343	SH2B adaptor protein 3.	Tyrosine-protein kinase.	0.631
G3NY16_GASAC	G3NRM9_GASAC	ENSGACP00000010236	ENSGACP00000007996	E1A binding protein p300 b.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.739
G3P6Y8_GASAC	G3PBM5_GASAC	ENSGACP00000013362	ENSGACP00000014999	Protein tyrosine phosphatase non-receptor type 6.	Tyrosine-protein kinase.	0.659
G3P6Y8_GASAC	SRC	ENSGACP00000013362	ENSGACP00000007343	Protein tyrosine phosphatase non-receptor type 6.	Tyrosine-protein kinase.	0.659
G3PBM5_GASAC	ABI1	ENSGACP00000014999	ENSGACP00000006752	Tyrosine-protein kinase.	Abl-interactor 1a.	0.587
G3PBM5_GASAC	G3NM14_GASAC	ENSGACP00000014999	ENSGACP00000006377	Tyrosine-protein kinase.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.697
G3PBM5_GASAC	G3NPQ0_GASAC	ENSGACP00000014999	ENSGACP00000007314	Tyrosine-protein kinase.	Glycoprotein Ib platelet subunit beta.	0.699
G3PBM5_GASAC	G3NRM9_GASAC	ENSGACP00000014999	ENSGACP00000007996	Tyrosine-protein kinase.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.662