(11 nodes) Biotin/lipoyl attachment network (Gasterosteus aculeatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3P3N9_GASAC	Acetyl-CoA carboxylase beta. (2241 aa)
	DLST	Dihydrolipoamide S-succinyltransferase. (450 aa)
	G3Q870_GASAC	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1179 aa)
	G3QAB5_GASAC	Acetyl-CoA carboxylase alpha. (2345 aa)
	G3QBP3_GASAC	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (641 aa)
	G3PJP7_GASAC	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (495 aa)
	G3PH15_GASAC	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (175 aa)
	G3PC07_GASAC	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (495 aa)
	G3NCK6_GASAC	Propionyl-CoA carboxylase subunit alpha. (713 aa)
	G3NRZ8_GASAC	Methylcrotonoyl-CoA carboxylase 1 (alpha). (712 aa)
	G3NXC0_GASAC	Dihydrolipoamide S-succinyltransferase. (460 aa)

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DLST	G3NCK6_GASAC	ENSGACP00000013932	ENSGACP00000003056	Dihydrolipoamide S-succinyltransferase.	Propionyl-CoA carboxylase subunit alpha.	0.696
DLST	G3NRZ8_GASAC	ENSGACP00000013932	ENSGACP00000008115	Dihydrolipoamide S-succinyltransferase.	Methylcrotonoyl-CoA carboxylase 1 (alpha).	0.696
DLST	G3P3N9_GASAC	ENSGACP00000013932	ENSGACP00000012212	Dihydrolipoamide S-succinyltransferase.	Acetyl-CoA carboxylase beta.	0.673
DLST	G3PC07_GASAC	ENSGACP00000013932	ENSGACP00000015131	Dihydrolipoamide S-succinyltransferase.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.968
DLST	G3PH15_GASAC	ENSGACP00000013932	ENSGACP00000016890	Dihydrolipoamide S-succinyltransferase.	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	0.871
DLST	G3PJP7_GASAC	ENSGACP00000013932	ENSGACP00000017827	Dihydrolipoamide S-succinyltransferase.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.776
DLST	G3Q870_GASAC	ENSGACP00000013932	ENSGACP00000026084	Dihydrolipoamide S-succinyltransferase.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.786
DLST	G3QAB5_GASAC	ENSGACP00000013932	ENSGACP00000026831	Dihydrolipoamide S-succinyltransferase.	Acetyl-CoA carboxylase alpha.	0.672
DLST	G3QBP3_GASAC	ENSGACP00000013932	ENSGACP00000027309	Dihydrolipoamide S-succinyltransferase.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.966
G3NCK6_GASAC	DLST	ENSGACP00000003056	ENSGACP00000013932	Propionyl-CoA carboxylase subunit alpha.	Dihydrolipoamide S-succinyltransferase.	0.696
G3NCK6_GASAC	G3NXC0_GASAC	ENSGACP00000003056	ENSGACP00000009989	Propionyl-CoA carboxylase subunit alpha.	Dihydrolipoamide S-succinyltransferase.	0.707
G3NCK6_GASAC	G3P3N9_GASAC	ENSGACP00000003056	ENSGACP00000012212	Propionyl-CoA carboxylase subunit alpha.	Acetyl-CoA carboxylase beta.	0.807
G3NCK6_GASAC	G3PC07_GASAC	ENSGACP00000003056	ENSGACP00000015131	Propionyl-CoA carboxylase subunit alpha.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.757
G3NCK6_GASAC	G3PJP7_GASAC	ENSGACP00000003056	ENSGACP00000017827	Propionyl-CoA carboxylase subunit alpha.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.936
G3NCK6_GASAC	G3Q870_GASAC	ENSGACP00000003056	ENSGACP00000026084	Propionyl-CoA carboxylase subunit alpha.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.881
G3NCK6_GASAC	G3QAB5_GASAC	ENSGACP00000003056	ENSGACP00000026831	Propionyl-CoA carboxylase subunit alpha.	Acetyl-CoA carboxylase alpha.	0.807
G3NCK6_GASAC	G3QBP3_GASAC	ENSGACP00000003056	ENSGACP00000027309	Propionyl-CoA carboxylase subunit alpha.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.759
G3NRZ8_GASAC	DLST	ENSGACP00000008115	ENSGACP00000013932	Methylcrotonoyl-CoA carboxylase 1 (alpha).	Dihydrolipoamide S-succinyltransferase.	0.696
G3NRZ8_GASAC	G3NXC0_GASAC	ENSGACP00000008115	ENSGACP00000009989	Methylcrotonoyl-CoA carboxylase 1 (alpha).	Dihydrolipoamide S-succinyltransferase.	0.696
G3NRZ8_GASAC	G3P3N9_GASAC	ENSGACP00000008115	ENSGACP00000012212	Methylcrotonoyl-CoA carboxylase 1 (alpha).	Acetyl-CoA carboxylase beta.	0.807