(19 nodes) Generation of second messenger molecules network (Gasterosteus aculeatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3PAN1_GASAC	Non-specific serine/threonine protein kinase. (539 aa)
	G3PIU6_GASAC	Non-specific serine/threonine protein kinase. (563 aa)
	G3PNI1_GASAC	GRB2 related adaptor protein 2a. (325 aa)
	G3PQ99_GASAC	Spinster homolog 1 (Drosophila). (488 aa)
	G3PZ17_GASAC	Uncharacterized protein. (388 aa)
	G3Q3J0_GASAC	Tyrosine-protein kinase. (613 aa)
	G3QA00_GASAC	Spinster homolog 3 (Drosophila). (479 aa)
	PAK3	Non-specific serine/threonine protein kinase. (578 aa)
	G3PFQ1_GASAC	Ig-like domain-containing protein. (286 aa)
	PAK2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (498 aa)
	G3P0R0_GASAC	SH3 domain-containing protein. (488 aa)
	G3NRZ9_GASAC	Ig_4 domain-containing protein. (175 aa)
	CD3D	Uncharacterized protein. (152 aa)
	G3NNU1_GASAC	IGv domain-containing protein. (132 aa)
	G3NNT3_GASAC	Uncharacterized protein. (137 aa)
	G3NLI8_GASAC	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1281 aa)
	G3NI48_GASAC	Zgc:91849. (983 aa)
	G3NI44_GASAC	Immunoglobulin superfamily, member 3. (1192 aa)
	G3N5Q3_GASAC	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1263 aa)

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD3D	G3N5Q3_GASAC	ENSGACP00000008114	ENSGACP00000000627	Uncharacterized protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.561
CD3D	G3NLI8_GASAC	ENSGACP00000008114	ENSGACP00000006201	Uncharacterized protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.538
CD3D	G3NNT3_GASAC	ENSGACP00000008114	ENSGACP00000006997	Uncharacterized protein.	Uncharacterized protein.	0.787
CD3D	G3NNU1_GASAC	ENSGACP00000008114	ENSGACP00000007005	Uncharacterized protein.	IGv domain-containing protein.	0.810
CD3D	G3NRZ9_GASAC	ENSGACP00000008114	ENSGACP00000008116	Uncharacterized protein.	Ig_4 domain-containing protein.	0.999
CD3D	G3P0R0_GASAC	ENSGACP00000008114	ENSGACP00000011183	Uncharacterized protein.	SH3 domain-containing protein.	0.513
CD3D	G3PFQ1_GASAC	ENSGACP00000008114	ENSGACP00000016425	Uncharacterized protein.	Ig-like domain-containing protein.	0.804
CD3D	G3PNI1_GASAC	ENSGACP00000008114	ENSGACP00000019164	Uncharacterized protein.	GRB2 related adaptor protein 2a.	0.814
CD3D	G3PZ17_GASAC	ENSGACP00000008114	ENSGACP00000022857	Uncharacterized protein.	Uncharacterized protein.	0.417
CD3D	G3Q3J0_GASAC	ENSGACP00000008114	ENSGACP00000024442	Uncharacterized protein.	Tyrosine-protein kinase.	0.711
G3N5Q3_GASAC	CD3D	ENSGACP00000000627	ENSGACP00000008114	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Uncharacterized protein.	0.561
G3N5Q3_GASAC	G3NI44_GASAC	ENSGACP00000000627	ENSGACP00000005004	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Immunoglobulin superfamily, member 3.	0.434
G3N5Q3_GASAC	G3NI48_GASAC	ENSGACP00000000627	ENSGACP00000005008	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Zgc:91849.	0.539
G3N5Q3_GASAC	G3NLI8_GASAC	ENSGACP00000000627	ENSGACP00000006201	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.846
G3N5Q3_GASAC	G3NNT3_GASAC	ENSGACP00000000627	ENSGACP00000006997	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Uncharacterized protein.	0.644
G3N5Q3_GASAC	G3NNU1_GASAC	ENSGACP00000000627	ENSGACP00000007005	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	IGv domain-containing protein.	0.688
G3N5Q3_GASAC	G3NRZ9_GASAC	ENSGACP00000000627	ENSGACP00000008116	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Ig_4 domain-containing protein.	0.587
G3N5Q3_GASAC	G3PAN1_GASAC	ENSGACP00000000627	ENSGACP00000014655	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Non-specific serine/threonine protein kinase.	0.666
G3N5Q3_GASAC	G3PFQ1_GASAC	ENSGACP00000000627	ENSGACP00000016425	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Ig-like domain-containing protein.	0.655
G3N5Q3_GASAC	G3PIU6_GASAC	ENSGACP00000000627	ENSGACP00000017525	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Non-specific serine/threonine protein kinase.	0.672