(78 nodes) p53-Independent G1/S DNA damage checkpoint network (Gasterosteus aculeatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3N417_GASAC	Proteasome inhibitor subunit 1. (259 aa)
	G3N4B7_GASAC	Proteasome subunit beta. (224 aa)
	G3N4G9_GASAC	Proteasome subunit beta 12. (217 aa)
	G3N4C1_GASAC	Proteasome subunit beta. (238 aa)
	G3N8Q6_GASAC	Proteasome subunit beta. (275 aa)
	G3N4D2_GASAC	Proteasome subunit beta. (276 aa)
	G3N4E8_GASAC	Uncharacterized protein. (240 aa)
	G3N4F0_GASAC	Proteasome subunit beta. (216 aa)
	G3N4F1_GASAC	Proteasome subunit beta 12. (217 aa)
	G3N4F2_GASAC	Proteasome subunit beta. (246 aa)
	G3N4F5_GASAC	Proteasome subunit beta. (275 aa)
	G3NMW7_GASAC	Proteasome subunit alpha type. (248 aa)
	G3N4H6_GASAC	Proteasome subunit beta. (275 aa)
	G3N556_GASAC	Proteasome subunit alpha type. (241 aa)
	G3N853_GASAC	Proteasome subunit beta. (235 aa)
	G3N8R0_GASAC	Proteasome subunit beta. (277 aa)
	G3N8R2_GASAC	Proteasome subunit beta. (274 aa)
	G3NA57_GASAC	Proteasome activator subunit 2. (245 aa)
	G3NAA9_GASAC	Proteasome subunit beta. (268 aa)
	G3NAN6_GASAC	Uncharacterized protein. (245 aa)
	G3NB47_GASAC	Proteasome subunit beta. (279 aa)
	G3NC06_GASAC	Proteasome activator subunit 1. (246 aa)
	G3NDU6_GASAC	Proteasome subunit beta 2. (119 aa)
	G3NDY9_GASAC	Proteasome activator subunit 4b. (1809 aa)
	G3NHP5_GASAC	Proteasome activator subunit 3. (256 aa)
	G3NI22_GASAC	Proteasome 26S subunit, non-ATPase 11b. (422 aa)
	G3NJ18_GASAC	Proteasome subunit alpha type. (255 aa)
	CDC25B	Cell division cycle 25B. (556 aa)
	G3NQH3_GASAC	Proteasome activator subunit 4a. (1826 aa)
	G3NQL6_GASAC	Proteasome activator subunit 3. (281 aa)
	G3NQM7_GASAC	Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (407 aa)
	G3NQQ6_GASAC	Proteasome subunit alpha type. (245 aa)
	G3NTT6_GASAC	Proteasome subunit alpha type. (264 aa)
	G3NV85_GASAC	Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (422 aa)
	PSMA4	Proteasome subunit alpha type. (261 aa)
	G3NZE4_GASAC	Proteasome 26S subunit, non-ATPase 9. (212 aa)
	G3P3M1_GASAC	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (878 aa)
	G3P3P1_GASAC	Uncharacterized protein. (281 aa)
	G3P3P2_GASAC	Proteasome 26S subunit, non-ATPase 6. (389 aa)
	G3P674_GASAC	Proteasome subunit beta; Belongs to the peptidase T1B family. (267 aa)
	G3P9I1_GASAC	FHA domain-containing protein. (185 aa)
	G3PCG6_GASAC	Ribosomal protein S27a. (158 aa)
	G3PE27_GASAC	KxDL motif containing 1. (184 aa)
	G3PET1_GASAC	Proteasome 26S subunit, non-ATPase 7. (336 aa)
	G3PFN1_GASAC	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (417 aa)
	G3PG43_GASAC	Proteasome subunit alpha type. (228 aa)
	G3PI51_GASAC	Proteasome 26S subunit, non-ATPase 8. (291 aa)
	G3PIQ9_GASAC	Proteasome subunit alpha type. (251 aa)
	G3PMH5_GASAC	Proteasome subunit beta. (274 aa)
	G3PPJ1_GASAC	Proteasome 26S subunit, non-ATPase 3. (518 aa)
	G3PQX6_GASAC	Proteasome 26S subunit, non-ATPase 14. (310 aa)
	G3PT17_GASAC	Proteasome 26S subunit, non-ATPase 13. (378 aa)
	G3PUL8_GASAC	Proteasome 26S subunit, ATPase 3. (444 aa)
	G3PUM8_GASAC	Proteasome subunit beta. (237 aa)
	G3PZP3_GASAC	Proteasome subunit alpha type. (261 aa)
	G3Q0Y9_GASAC	Proteasome 26S subunit, non-ATPase 5. (504 aa)
	G3Q285_GASAC	Proteasome subunit beta. (205 aa)
	G3Q2W4_GASAC	Proteasome subunit beta. (277 aa)
	G3Q3L8_GASAC	Proteasome 26S subunit, non-ATPase 10. (232 aa)
	G3Q3S9_GASAC	Proteasome subunit beta. (281 aa)
	G3NQG7_GASAC	Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (226 aa)
	G3Q3T1_GASAC	Proteasome 26S subunit, non-ATPase 12. (486 aa)
	G3Q700_GASAC	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (440 aa)
	G3QA52_GASAC	Ubiquitin B. (611 aa)
	G3QBM7_GASAC	Checkpoint kinase 1; Belongs to the protein kinase superfamily. (474 aa)
	G3N4H5_GASAC	Proteasome subunit beta. (274 aa)
	ENSGACP00000000193	Proteasome 20S subunit beta 12. (217 aa)
	G3N4B5_GASAC	Proteasome subunit beta. (216 aa)
	G3N4H1_GASAC	Proteasome subunit beta. (275 aa)
	G3N4H0_GASAC	Proteasome subunit beta. (274 aa)
	ENSGACP00000000189	Proteasome 20S subunit beta 12. (217 aa)
	ENSGACP00000000188	Proteasome 20S subunit beta 9a. (216 aa)
	ENSGACP00000000183	Proteasome 20S subunit beta 8A. (275 aa)
	G3N4G2_GASAC	Proteasome subunit beta. (274 aa)
	ENSGACP00000000181	Proteasome 20S subunit beta 12. (217 aa)
	G3N4G8_GASAC	Proteasome subunit beta. (216 aa)
	G3NNG5_GASAC	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (367 aa)
	PSMD11	PCI domain-containing protein. (377 aa)

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC25B	G3NA57_GASAC	ENSGACP00000006407	ENSGACP00000002200	Cell division cycle 25B.	Proteasome activator subunit 2.	0.586
CDC25B	G3NC06_GASAC	ENSGACP00000006407	ENSGACP00000002855	Cell division cycle 25B.	Proteasome activator subunit 1.	0.586
CDC25B	G3NDY9_GASAC	ENSGACP00000006407	ENSGACP00000003540	Cell division cycle 25B.	Proteasome activator subunit 4b.	0.606
CDC25B	G3NHP5_GASAC	ENSGACP00000006407	ENSGACP00000004854	Cell division cycle 25B.	Proteasome activator subunit 3.	0.645
CDC25B	G3NNG5_GASAC	ENSGACP00000006407	ENSGACP00000006879	Cell division cycle 25B.	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family.	0.675
CDC25B	G3NQH3_GASAC	ENSGACP00000006407	ENSGACP00000007589	Cell division cycle 25B.	Proteasome activator subunit 4a.	0.606
CDC25B	G3NQL6_GASAC	ENSGACP00000006407	ENSGACP00000007632	Cell division cycle 25B.	Proteasome activator subunit 3.	0.640
CDC25B	G3NQM7_GASAC	ENSGACP00000006407	ENSGACP00000007643	Cell division cycle 25B.	Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family.	0.666
CDC25B	G3NV85_GASAC	ENSGACP00000006407	ENSGACP00000009254	Cell division cycle 25B.	Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family.	0.678
CDC25B	G3P3P2_GASAC	ENSGACP00000006407	ENSGACP00000012215	Cell division cycle 25B.	Proteasome 26S subunit, non-ATPase 6.	0.687
CDC25B	G3P674_GASAC	ENSGACP00000006407	ENSGACP00000013097	Cell division cycle 25B.	Proteasome subunit beta; Belongs to the peptidase T1B family.	0.662
CDC25B	G3P9I1_GASAC	ENSGACP00000006407	ENSGACP00000014255	Cell division cycle 25B.	FHA domain-containing protein.	0.984
CDC25B	G3PCG6_GASAC	ENSGACP00000006407	ENSGACP00000015290	Cell division cycle 25B.	Ribosomal protein S27a.	0.706
CDC25B	G3PI51_GASAC	ENSGACP00000006407	ENSGACP00000017278	Cell division cycle 25B.	Proteasome 26S subunit, non-ATPase 8.	0.707
CDC25B	G3PIQ9_GASAC	ENSGACP00000006407	ENSGACP00000017488	Cell division cycle 25B.	Proteasome subunit alpha type.	0.661
CDC25B	G3PQX6_GASAC	ENSGACP00000006407	ENSGACP00000020011	Cell division cycle 25B.	Proteasome 26S subunit, non-ATPase 14.	0.670
CDC25B	G3PT17_GASAC	ENSGACP00000006407	ENSGACP00000020753	Cell division cycle 25B.	Proteasome 26S subunit, non-ATPase 13.	0.672
CDC25B	G3PUL8_GASAC	ENSGACP00000006407	ENSGACP00000021305	Cell division cycle 25B.	Proteasome 26S subunit, ATPase 3.	0.669
CDC25B	G3Q0Y9_GASAC	ENSGACP00000006407	ENSGACP00000023537	Cell division cycle 25B.	Proteasome 26S subunit, non-ATPase 5.	0.673
CDC25B	G3Q285_GASAC	ENSGACP00000006407	ENSGACP00000023984	Cell division cycle 25B.	Proteasome subunit beta.	0.667