31 items (Gasterosteus aculeatus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3N4P3_GASAC	DUF1943 domain-containing protein. (96 aa)
	G3P5Q0_GASAC	Uncharacterized protein. (1654 aa)
	G3P5G9_GASAC	Vitellogenin domain-containing protein. (984 aa)
	G3P573_GASAC	Uncharacterized protein. (445 aa)
	G3P570_GASAC	Vitellogenin domain-containing protein. (1648 aa)
	G3P546_GASAC	Apolipoprotein Bb, tandem duplicate 2. (3689 aa)
	G3P4L3_GASAC	Vitellogenin 3, phosvitinless. (1271 aa)
	G3NZV2_GASAC	Fibrinogen C-terminal domain-containing protein. (440 aa)
	G3NV04_GASAC	Angiopoietin-like 3. (471 aa)
	G3NRQ2_GASAC	Apolipoprotein A-Ib. (263 aa)
	G3Q9N6_GASAC	DUF1943 domain-containing protein. (96 aa)
	G3Q2E0_GASAC	Protein disulfide-isomerase. (521 aa)
	G3Q146_GASAC	Microsomal triglyceride transfer protein. (885 aa)
	G3PX45_GASAC	Protein disulfide-isomerase. (522 aa)
	ANGPTL3	Angiopoietin like 3. (480 aa)
	G3PU39_GASAC	Uncharacterized protein. (552 aa)
	G3PSD9_GASAC	Angiopoietin-like 4. (479 aa)
	G3PHL5_GASAC	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (647 aa)
	G3PC60_GASAC	Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family. (831 aa)
	G3PBS0_GASAC	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (524 aa)
	G3PBM2_GASAC	PLAT domain-containing protein. (511 aa)
	G3NR28_GASAC	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (808 aa)
	G3NPZ9_GASAC	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (584 aa)
	G3NLF2_GASAC	Lipase, endothelial. (500 aa)
	G3NGQ8_GASAC	Apolipoprotein Eb. (264 aa)
	G3NFZ0_GASAC	Lecithin-cholesterol acyltransferase. (423 aa)
	G3P9C5_GASAC	Uncharacterized protein. (265 aa)
	G3NFN7_GASAC	Phospholipid transfer protein. (497 aa)
	G3NCX8_GASAC	Apolipoprotein Ea. (286 aa)
	G3NCV4_GASAC	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (500 aa)
	G3N6J1_GASAC	Uncharacterized protein. (230 aa)

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANGPTL3	G3NR28_GASAC	ENSGACP00000021392	ENSGACP00000007794	Angiopoietin like 3.	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.573
ANGPTL3	G3NZV2_GASAC	ENSGACP00000021392	ENSGACP00000010875	Angiopoietin like 3.	Fibrinogen C-terminal domain-containing protein.	0.734
ANGPTL3	G3PBM2_GASAC	ENSGACP00000021392	ENSGACP00000014996	Angiopoietin like 3.	PLAT domain-containing protein.	0.708
ANGPTL3	G3PBS0_GASAC	ENSGACP00000021392	ENSGACP00000015044	Angiopoietin like 3.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.708
ANGPTL3	G3PSD9_GASAC	ENSGACP00000021392	ENSGACP00000020525	Angiopoietin like 3.	Angiopoietin-like 4.	0.732
G3N4P3_GASAC	G3N6J1_GASAC	ENSGACP00000000263	ENSGACP00000000916	DUF1943 domain-containing protein.	Uncharacterized protein.	0.728
G3N4P3_GASAC	G3NCV4_GASAC	ENSGACP00000000263	ENSGACP00000003154	DUF1943 domain-containing protein.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.736
G3N4P3_GASAC	G3NCX8_GASAC	ENSGACP00000000263	ENSGACP00000003178	DUF1943 domain-containing protein.	Apolipoprotein Ea.	0.801
G3N4P3_GASAC	G3NFN7_GASAC	ENSGACP00000000263	ENSGACP00000004142	DUF1943 domain-containing protein.	Phospholipid transfer protein.	0.565
G3N4P3_GASAC	G3NGQ8_GASAC	ENSGACP00000000263	ENSGACP00000004514	DUF1943 domain-containing protein.	Apolipoprotein Eb.	0.781
G3N4P3_GASAC	G3NR28_GASAC	ENSGACP00000000263	ENSGACP00000007794	DUF1943 domain-containing protein.	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.833
G3N4P3_GASAC	G3NRQ2_GASAC	ENSGACP00000000263	ENSGACP00000008005	DUF1943 domain-containing protein.	Apolipoprotein A-Ib.	0.859
G3N4P3_GASAC	G3PX45_GASAC	ENSGACP00000000263	ENSGACP00000022184	DUF1943 domain-containing protein.	Protein disulfide-isomerase.	0.695
G3N4P3_GASAC	G3Q146_GASAC	ENSGACP00000000263	ENSGACP00000023594	DUF1943 domain-containing protein.	Microsomal triglyceride transfer protein.	0.897
G3N4P3_GASAC	G3Q2E0_GASAC	ENSGACP00000000263	ENSGACP00000024039	DUF1943 domain-containing protein.	Protein disulfide-isomerase.	0.695
G3N6J1_GASAC	G3N4P3_GASAC	ENSGACP00000000916	ENSGACP00000000263	Uncharacterized protein.	DUF1943 domain-containing protein.	0.728
G3N6J1_GASAC	G3NCV4_GASAC	ENSGACP00000000916	ENSGACP00000003154	Uncharacterized protein.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.844
G3N6J1_GASAC	G3NFN7_GASAC	ENSGACP00000000916	ENSGACP00000004142	Uncharacterized protein.	Phospholipid transfer protein.	0.689
G3N6J1_GASAC	G3NRQ2_GASAC	ENSGACP00000000916	ENSGACP00000008005	Uncharacterized protein.	Apolipoprotein A-Ib.	0.437
G3N6J1_GASAC	G3P4L3_GASAC	ENSGACP00000000916	ENSGACP00000012536	Uncharacterized protein.	Vitellogenin 3, phosvitinless.	0.617