STRINGSTRING
ADV44481.1 ADV44481.1 ADV45241.1 ADV45241.1 ADV45240.1 ADV45240.1 ADV45121.1 ADV45121.1 ADV45073.1 ADV45073.1 ADV44958.1 ADV44958.1 hisC hisC ADV44899.1 ADV44899.1 serC serC gcvP gcvP ADV44552.1 ADV44552.1 glyA glyA ADV44411.1 ADV44411.1 ADV44287.1 ADV44287.1 ADV44224.1 ADV44224.1 ADV44127.1 ADV44127.1 ADV44099.1 ADV44099.1 bioB bioB ADV44064.1 ADV44064.1 ADV44058.1 ADV44058.1 dapL dapL ADV43917.1 ADV43917.1 kbl kbl ADV42537.1 ADV42537.1 ADV42313.1 ADV42313.1 ADV42244.1 ADV42244.1 ADV42104.1 ADV42104.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ADV44481.1Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: bfs:BF2110 putative amino acid transferase; PFAM: aminotransferase class I and II; SPTR: Putative uncharacterized protein; PFAM: Aminotransferase class I and II. (438 aa)
ADV45241.1Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR000277; KEGG: bfr:BF0991 O-acetylhomoserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Putative uncharacterized protein; PFAM: Cys/Met metabolism PLP-dependent enzyme. (391 aa)
ADV45240.1Aminotransferase class I and II; COGs: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; InterPro IPR004839; KEGG: pdi:BDI_2080 putative aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aminotransferase, classes I and II; PFAM: Aminotransferase class I and II. (396 aa)
ADV45121.1COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR006235: IPR000277; KEGG: bfs:BF3351 putative cysteine biosynthesis related protein; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: Cysteine synthase; SPTR: Putative uncharacterized protein; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase. (426 aa)
ADV45073.1COGs: COG2008 Threonine aldolase; InterPro IPR001597; KEGG: bfs:BF3212 putative aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: Threonine aldolase; SPTR: Putative uncharacterized protein; PFAM: Beta-eliminating lyase. (339 aa)
ADV44958.1COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR006235: IPR000277; KEGG: pdi:BDI_2552 O-acetylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: Cysteine synthase; SPTR: O-acetylhomoserine (Thiol)-lyase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase. (429 aa)
hisCCOGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005861: IPR004839: IPR001917; KEGG: bth:BT_0202 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (345 aa)
ADV44899.1DegT/DnrJ/EryC1/StrS aminotransferase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: bfr:BF3659 putative aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: Aminotransferase, DegT/DnrJ/EryC1/StrS family; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; Belongs to the DegT/DnrJ/EryC1 family. (368 aa)
serCPhosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (355 aa)
gcvPGlycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (949 aa)
ADV44552.1COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004838: IPR004839: IPR001176; KEGG: pdi:BDI_1415 hemolysin erythrocyte lysis protein 2; PFAM: aminotransferase class I and II; PRIAM: Histidinol-phosphate transaminase; SPTR: Hemolysin erythrocyte lysis protein 2; PFAM: Nucleotidyl transferase; Aminotransferase class I and II. (602 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (426 aa)
ADV44411.1DegT/DnrJ/EryC1/StrS aminotransferase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: pdi:BDI_3641 putative aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: Putative uncharacterized protein; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; Belongs to the DegT/DnrJ/EryC1 family. (413 aa)
ADV44287.1Serine palmitoyltransferase; COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterPro IPR004839: IPR001917; KEGG: bvu:BVU_3166 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; PRIAM: Glycine C-acetyltransferase; SPTR: Putative uncharacterized protein; PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase. (395 aa)
ADV44224.1L-threonine O-3-phosphate decarboxylase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839: IPR004838; KEGG: bfs:BF2523 putative histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Putative uncharacterized protein; PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase. (343 aa)
ADV44127.1Hypothetical protein; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; KEGG: pmh:P9215_14191 pyridoxal phosphate-dependent enzyme; SPTR: Predicted protein; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; Belongs to the DegT/DnrJ/EryC1 family. (372 aa)
ADV44099.1DegT/DnrJ/EryC1/StrS aminotransferase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: pdi:BDI_3641 putative aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: Putative uncharacterized protein; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; Belongs to the DegT/DnrJ/EryC1 family. (413 aa)
bioBAdenosylmethionine-8-amino-7-oxononanoate aminotransferase apoenzyme; Catalyzes two activities which are involved in the biotine biosynthesis: the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism, and the transfer of the alpha-amino group from S-adenosyl-L- methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8- diaminopelargonic acid (DAPA); In the C-terminal section; belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (744 aa)
ADV44064.18-amino-7-oxononanoate synthase; COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterPro IPR004839: IPR004723; KEGG: bth:BT_1443 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; PRIAM: 8-amino-7-oxononanoate synthase; SPTR: Putative uncharacterized protein; TIGRFAM: 8-amino-7-oxononanoate synthase; PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase. (384 aa)
ADV44058.1Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176: IPR004839; KEGG: bfs:BF1601 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Putative uncharacterized protein; PFAM: Aminotransferase class I and II. (399 aa)
dapLLL-diaminopimelate aminotransferase apoenzyme; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. (411 aa)
ADV43917.1UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653: IPR020026; KEGG: gfo:GFO_2027 SpsC-like DegT/DnrJ/EryC1/StrS family aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: Putative uncharacterized protein; TIGRFAM: UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; TIGRFAM: UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (387 aa)
kbl2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (395 aa)
ADV42537.1COGs: COG0520 Selenocysteine lyase; InterPro IPR010970: IPR000192; KEGG: bth:BT_3409 aminotransferase, putative cysteine desulfurase; PFAM: aminotransferase class V; SPTR: Putative uncharacterized protein; TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurases, SufS subfamily; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (403 aa)
ADV42313.1Aminotransferase class-III; COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR005814; KEGG: bth:BT_3758 acetylornithine aminotransferase; PFAM: aminotransferase class-III; SPTR: Putative uncharacterized protein; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (374 aa)
ADV42244.1Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176: IPR004838: IPR004839; KEGG: bfs:BF0545 putative aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aspartate aminotransferase; PFAM: Aminotransferase class I and II. (397 aa)
ADV42104.1Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004838: IPR004839; KEGG: bfs:BF3716 putative aminotransferase; PFAM: aminotransferase class I and II; SPTR: Putative uncharacterized protein; PFAM: Aminotransferase class I and II. (393 aa)
Your Current Organism:
Bacteroides helcogenes
NCBI taxonomy Id: 693979
Other names: B. helcogenes P 36-108, Bacteroides helcogenes DSM 20613, Bacteroides helcogenes P 36-108, Bacteroides helcogenes str. P 36-108, Bacteroides helcogenes strain P 36-108
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