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folK folK folB folB folP folP MOC_0682 MOC_0682 MOC_0686 MOC_0686 queF queF MOC_2030 MOC_2030 pabB pabB queC queC queD queD mobA mobA moaE moaE queE queE MOC_2994 MOC_2994 MOC_2996 MOC_2996 moaA moaA ribB ribB MOC_3141 MOC_3141 MOC_3477 MOC_3477 moaC moaC MOC_3887 MOC_3887 MOC_3980 MOC_3980 MOC_3981 MOC_3981 moaB moaB MOC_4443 MOC_4443 moaA-2 moaA-2 MOC_5184 MOC_5184 MOC_5323 MOC_5323 folE folE MOC_5920 MOC_5920
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (156 aa)
folBDihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (125 aa)
folPDihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (284 aa)
MOC_0682Beta-ribofuranosylaminobenzene 5'-phosphate synthase. (310 aa)
MOC_0686Alpha-L-glutamate ligase; Belongs to the RimK family. (302 aa)
queF7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (153 aa)
MOC_2030Glutamine amidotransferase of anthranilate synthase. (201 aa)
pabBPara-aminobenzoate synthase, component I. (462 aa)
queCExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (225 aa)
queDQueuosine biosynthesis protein QueD. (118 aa)
mobAMolybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (214 aa)
moaEMolybdopterin biosynthesis protein MoaE. (155 aa)
queEProtein of unassigned function; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (210 aa)
MOC_2994Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (403 aa)
MOC_2996Molybdenum cofactor synthesis domain protein. (184 aa)
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (340 aa)
ribB3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (358 aa)
MOC_3141Transcriptional coactivator/pterin dehydratase. (125 aa)
MOC_3477Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (409 aa)
moaCMolybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (163 aa)
MOC_3887Bifunctional folylpolyglutamate/dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. (441 aa)
MOC_39804-diphosphocytidyl-2C-methyl-D-erythritol synthase. (199 aa)
MOC_3981Molybdopterin binding domain protein. (347 aa)
moaBMolybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (185 aa)
MOC_4443Dihydrofolate reductase. (136 aa)
moaA-2Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (350 aa)
MOC_5184Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (163 aa)
MOC_5323Putative alkaline phosphatase. (523 aa)
folEGTP cyclohydrolase I. (252 aa)
MOC_5920Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (416 aa)
Your Current Organism:
Methylobacterium oryzae
NCBI taxonomy Id: 693986
Other names: M. oryzae CBMB20, Methylobacterium oryzae CBMB20, Methylobacterium oryzae str. CBMB20, Methylobacterium oryzae strain CBMB20
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