(71 nodes) Mixed, incl. RAB geranylgeranylation, and Exocyst network (Ixodes scapularis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B7P0P5_IXOSC	FIP-RBD domain-containing protein. (259 aa)
	B7P0S2_IXOSC	WD-repeat protein, putative. (479 aa)
	B7P145_IXOSC	Exocyst componenet sec8, putative (Fragment). (914 aa)
	B7P1S2_IXOSC	RAB geranylgeranyl transferase alpha subunit, putative (Fragment). (514 aa)
	B7P2F7_IXOSC	RAS-related protein, putative (Fragment). (175 aa)
	B7P369_IXOSC	Zinc finger protein, putative. (222 aa)
	B7P4G4_IXOSC	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (661 aa)
	B7P5F2_IXOSC	RAB GTPase-activating protein, putative (Fragment). (461 aa)
	B7P5X7_IXOSC	Exocyst complex component sec6, putative. (751 aa)
	B7PAD8_IXOSC	RabGAP domain-containing protein, putative. (504 aa)
	B7PAE0_IXOSC	RAS-related protein, putative. (215 aa)
	B7PAF7_IXOSC	Uncharacterized protein. (121 aa)
	B7PCL3_IXOSC	Protein MICAL-3, putative (Fragment). (610 aa)
	B7PCL4_IXOSC	BMERB domain-containing protein. (320 aa)
	B7PFL2_IXOSC	RAS-related protein, putative. (155 aa)
	B7PFZ5_IXOSC	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (752 aa)
	B7PIZ1_IXOSC	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (446 aa)
	B7PJC2_IXOSC	GTPase-activating protein gyp2, putative (Fragment). (286 aa)
	B7PJP6_IXOSC	Vps51/Vps67 protein, putative. (359 aa)
	B7PJS5_IXOSC	Sec10, putative. (632 aa)
	B7PKQ2_IXOSC	Vacuolar assembly/sorting protein VPS9, putative (Fragment). (407 aa)
	B7PKQ3_IXOSC	A20 family zinc finger domaincontaining protein. (91 aa)
	B7PL79_IXOSC	RAB geranylgeranyl transferase alpha subunit, putative. (174 aa)
	B7PLK7_IXOSC	RAS-related protein, putative. (216 aa)
	B7PMB7_IXOSC	FYVE-type domain-containing protein. (215 aa)
	B7PMB8_IXOSC	Tropomyosin, putative. (396 aa)
	B7PNJ7_IXOSC	RAB-20, putative. (215 aa)
	B7PQE2_IXOSC	EF-Hand domain-containing protein, putative. (144 aa)
	B7PQG5_IXOSC	Rab-GAP TBC domain-containing protein. (676 aa)
	B7PQG8_IXOSC	TBC domaincontaining protein. (482 aa)
	B7PQS4_IXOSC	EF-hand domain-containing protein. (207 aa)
	B7PR09_IXOSC	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (860 aa)
	B7PRU2_IXOSC	Growth hormone regulated Tbc protein, putative (Fragment). (317 aa)
	B7PRX3_IXOSC	RAB geranylgeranyl transferase alpha subunit, putative. (210 aa)
	B7PSW3_IXOSC	Uncharacterized protein. (190 aa)
	B7PT87_IXOSC	Translational initiation factor IF2, putative. (99 aa)
	B7PTH0_IXOSC	Ankyrin repeat containing protein. (508 aa)
	B7PTH1_IXOSC	Ankyrin repeat containing protein. (570 aa)
	B7PTV6_IXOSC	FYVE-type domain-containing protein. (753 aa)
	B7PU44_IXOSC	RabX4 family protein. (59 aa)
	B7PVE3_IXOSC	Exocyst complex component sec3, putative. (851 aa)
	B7PVH6_IXOSC	CABIT domain-containing protein. (621 aa)
	B7PXW6_IXOSC	RAS-related protein, putative. (148 aa)
	B7PZ00_IXOSC	Uncharacterized protein. (136 aa)
	B7Q2W4_IXOSC	RAS-related protein, putative (Fragment). (217 aa)
	B7Q2X8_IXOSC	Geranylgeranyl transferase type II beta subunit, putative. (94 aa)
	B7Q4D2_IXOSC	RAS-related protein, putative (Fragment). (149 aa)
	B7Q4D3_IXOSC	Rab39 family protein. (78 aa)
	B7Q5G4_IXOSC	Endocytosis/signaling protein EHD1, putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (324 aa)
	B7Q5G5_IXOSC	Past1 family protein. (210 aa)
	B7Q5R1_IXOSC	Vacuolar protein-sorting protein, putative; Belongs to the STXBP/unc-18/SEC1 family. (468 aa)
	B7Q699_IXOSC	GTP-binding protein RAB-32, putative (Fragment). (178 aa)
	B7Q6I7_IXOSC	Endocytosis/signaling protein EHD1, putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (538 aa)
	B7Q7R1_IXOSC	RAS-related protein, putative. (208 aa)
	B7QA33_IXOSC	Located at OATL1, putative (Fragment). (590 aa)
	B7QBI6_IXOSC	Small GTPase, putative. (194 aa)
	B7QBL7_IXOSC	Schwannomin interacting protein, putative. (251 aa)
	B7QCS6_IXOSC	RAS-related protein, putative (Fragment). (95 aa)
	B7QDB4_IXOSC	RAS-related protein, putative. (150 aa)
	B7QFX7_IXOSC	RAB-9 and, putative. (204 aa)
	B7QGE0_IXOSC	RAB GTPase, putative. (458 aa)
	B7QGJ1_IXOSC	C2H2-type domain-containing protein. (502 aa)
	B7QHS7_IXOSC	RAS-related protein, putative (Fragment). (218 aa)
	B7QHT0_IXOSC	Bhlh transcription factor, putative (Fragment). (125 aa)
	B7QI18_IXOSC	RAB GDP/GTP exchange factor, putative. (989 aa)
	B7QIZ6_IXOSC	Rab proteins geranylgeranyltransferase component A, putative. (722 aa)
	B7QJK3_IXOSC	RAB-6 GTPase activating protein, putative. (210 aa)
	B7QJM3_IXOSC	GAPVD1 protein, putative (Fragment). (271 aa)
	B7QJM4_IXOSC	Uncharacterized protein. (301 aa)
	B7QK75_IXOSC	Uncharacterized protein. (148 aa)
	B7QK76_IXOSC	Rabin, putative. (403 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P0P5_IXOSC	B7P4G4_IXOSC	B7P0P5	B7P4G4	FIP-RBD domain-containing protein.	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	0.704
B7P0P5_IXOSC	B7P5X7_IXOSC	B7P0P5	B7P5X7	FIP-RBD domain-containing protein.	Exocyst complex component sec6, putative.	0.620
B7P0P5_IXOSC	B7PFZ5_IXOSC	B7P0P5	B7PFZ5	FIP-RBD domain-containing protein.	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	0.670
B7P0P5_IXOSC	B7PQE2_IXOSC	B7P0P5	B7PQE2	FIP-RBD domain-containing protein.	EF-Hand domain-containing protein, putative.	0.403
B7P0P5_IXOSC	B7PR09_IXOSC	B7P0P5	B7PR09	FIP-RBD domain-containing protein.	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.	0.646
B7P0P5_IXOSC	B7Q2W4_IXOSC	B7P0P5	B7Q2W4	FIP-RBD domain-containing protein.	RAS-related protein, putative (Fragment).	0.486
B7P0P5_IXOSC	B7QGE0_IXOSC	B7P0P5	B7QGE0	FIP-RBD domain-containing protein.	RAB GTPase, putative.	0.403
B7P0P5_IXOSC	B7QHS7_IXOSC	B7P0P5	B7QHS7	FIP-RBD domain-containing protein.	RAS-related protein, putative (Fragment).	0.423
B7P0P5_IXOSC	B7QK75_IXOSC	B7P0P5	B7QK75	FIP-RBD domain-containing protein.	Uncharacterized protein.	0.749
B7P0P5_IXOSC	B7QK76_IXOSC	B7P0P5	B7QK76	FIP-RBD domain-containing protein.	Rabin, putative.	0.749
B7P0S2_IXOSC	B7QA33_IXOSC	B7P0S2	B7QA33	WD-repeat protein, putative.	Located at OATL1, putative (Fragment).	0.578
B7P145_IXOSC	B7P4G4_IXOSC	B7P145	B7P4G4	Exocyst componenet sec8, putative (Fragment).	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	0.998
B7P145_IXOSC	B7P5X7_IXOSC	B7P145	B7P5X7	Exocyst componenet sec8, putative (Fragment).	Exocyst complex component sec6, putative.	0.999
B7P145_IXOSC	B7PAD8_IXOSC	B7P145	B7PAD8	Exocyst componenet sec8, putative (Fragment).	RabGAP domain-containing protein, putative.	0.455
B7P145_IXOSC	B7PAF7_IXOSC	B7P145	B7PAF7	Exocyst componenet sec8, putative (Fragment).	Uncharacterized protein.	0.535
B7P145_IXOSC	B7PFZ5_IXOSC	B7P145	B7PFZ5	Exocyst componenet sec8, putative (Fragment).	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	0.998
B7P145_IXOSC	B7PJP6_IXOSC	B7P145	B7PJP6	Exocyst componenet sec8, putative (Fragment).	Vps51/Vps67 protein, putative.	0.998
B7P145_IXOSC	B7PJS5_IXOSC	B7P145	B7PJS5	Exocyst componenet sec8, putative (Fragment).	Sec10, putative.	0.999
B7P145_IXOSC	B7PQE2_IXOSC	B7P145	B7PQE2	Exocyst componenet sec8, putative (Fragment).	EF-Hand domain-containing protein, putative.	0.535
B7P145_IXOSC	B7PQS4_IXOSC	B7P145	B7PQS4	Exocyst componenet sec8, putative (Fragment).	EF-hand domain-containing protein.	0.535