(46 nodes) SERine Proteinase INhibitors, and Angiotensin-converting enzyme network (Ixodes scapularis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B7P1G7_IXOSC	Angiotensin-converting enzyme. (320 aa)
	B7P1G8_IXOSC	Serpin, putative; Belongs to the serpin family. (391 aa)
	B7P2R8_IXOSC	Serpin-2, putative; Belongs to the serpin family. (183 aa)
	B7P2Z9_IXOSC	Serpin, putative (Fragment); Belongs to the serpin family. (158 aa)
	B7P4B2_IXOSC	Thrombin inhibitor, putative; Belongs to the serpin family. (374 aa)
	B7P5V9_IXOSC	Leucine-rich transmembrane protein, putative. (818 aa)
	B7P9C8_IXOSC	Angiotensin-converting enzyme. (308 aa)
	B7P9J9_IXOSC	Angiotensin-converting enzyme. (586 aa)
	B7P9V6_IXOSC	Peptidyldipeptidase A, putative. (98 aa)
	B7PAU7_IXOSC	Serpin 7 precursor, putative; Belongs to the serpin family. (354 aa)
	B7PGP4_IXOSC	Serpin 2 precursor, putative; Belongs to the serpin family. (394 aa)
	B7PH24_IXOSC	Serine protease inhibitor, putative; Belongs to the serpin family. (703 aa)
	B7PKZ6_IXOSC	Serpin 2 precursor, putative; Belongs to the serpin family. (375 aa)
	B7PLW5_IXOSC	Serpin, putative (Fragment); Belongs to the serpin family. (180 aa)
	B7PN89_IXOSC	Serpin-2 precursor, putative; Belongs to the serpin family. (276 aa)
	B7PNJ5_IXOSC	Serine proteinase inhibitor, putative. (123 aa)
	B7PNY9_IXOSC	Angiotensin-converting enzyme. (513 aa)
	B7PRI2_IXOSC	Cystine-binding periplasmic protein, putative; Belongs to the serpin family. (178 aa)
	B7PST4_IXOSC	Serpin-4 precursor, putative; Belongs to the serpin family. (213 aa)
	B7PVJ0_IXOSC	Thrombin inhibitor, putative; Belongs to the serpin family. (174 aa)
	B7PVT7_IXOSC	Uncharacterized protein. (232 aa)
	B7PXL6_IXOSC	Angiotensin-converting enzyme. (330 aa)
	B7Q0E8_IXOSC	Serpin 7 precursor, putative; Belongs to the serpin family. (374 aa)
	B7Q2U8_IXOSC	Serpin, putative; Belongs to the serpin family. (129 aa)
	B7Q5W5_IXOSC	Serpin, putative; Belongs to the serpin family. (121 aa)
	B7Q5W6_IXOSC	Serpin-2 precursor, putative; Belongs to the serpin family. (249 aa)
	B7Q683_IXOSC	Serpin 2 precursor, putative; Belongs to the serpin family. (394 aa)
	B7Q685_IXOSC	Serpin 2 precursor, putative; Belongs to the serpin family. (385 aa)
	B7Q6L5_IXOSC	IG-like C2-type domain-containing protein, putative. (318 aa)
	B7Q8M7_IXOSC	Serpin-2 precursor, putative; Belongs to the serpin family. (350 aa)
	B7QCV3_IXOSC	No-mechanoreceptor potential A, putative. (1131 aa)
	B7QDU0_IXOSC	PAN domaincontaining protein. (153 aa)
	B7QGS1_IXOSC	Angiotensin-converting enzyme. (182 aa)
	B7QJF1_IXOSC	Serpin-8 precursor, putative; Belongs to the serpin family. (455 aa)
	B7QL30_IXOSC	Serpin-2, putative; Belongs to the serpin family. (234 aa)
	B7QL31_IXOSC	Serpin-1 precursor, putative; Belongs to the serpin family. (390 aa)
	B7QL32_IXOSC	Secreted salivary gland peptide, putative; Belongs to the serpin family. (463 aa)
	B7QL35_IXOSC	Secreted salivary gland peptide, putative; Belongs to the serpin family. (289 aa)
	B7QL36_IXOSC	Serpin-4 precursor, putative; Belongs to the serpin family. (393 aa)
	B7QL37_IXOSC	Serpin-1 precursor, putative; Belongs to the serpin family. (176 aa)
	B7QLU5_IXOSC	Serpin-2 precursor, putative; Belongs to the serpin family. (365 aa)
	B7QM31_IXOSC	Serpin, putative; Belongs to the serpin family. (469 aa)
	B7QMB3_IXOSC	Neprilysin, putative (Fragment). (613 aa)
	B7QNY0_IXOSC	Serpin-2, putative; Belongs to the serpin family. (396 aa)
	B7QNY6_IXOSC	Serine proteinase inhibitor serpin-3, putative; Belongs to the serpin family. (396 aa)
	B7QP26_IXOSC	Serpin-8 precursor, putative; Belongs to the serpin family. (177 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P1G7_IXOSC	B7P9V6_IXOSC	B7P1G7	B7P9V6	Angiotensin-converting enzyme.	Peptidyldipeptidase A, putative.	0.490
B7P2R8_IXOSC	B7PN89_IXOSC	B7P2R8	B7PN89	Serpin-2, putative; Belongs to the serpin family.	Serpin-2 precursor, putative; Belongs to the serpin family.	0.538
B7P2R8_IXOSC	B7PST4_IXOSC	B7P2R8	B7PST4	Serpin-2, putative; Belongs to the serpin family.	Serpin-4 precursor, putative; Belongs to the serpin family.	0.537
B7P2R8_IXOSC	B7Q5W6_IXOSC	B7P2R8	B7Q5W6	Serpin-2, putative; Belongs to the serpin family.	Serpin-2 precursor, putative; Belongs to the serpin family.	0.537
B7P2R8_IXOSC	B7QL30_IXOSC	B7P2R8	B7QL30	Serpin-2, putative; Belongs to the serpin family.	Serpin-2, putative; Belongs to the serpin family.	0.537
B7P2Z9_IXOSC	B7PN89_IXOSC	B7P2Z9	B7PN89	Serpin, putative (Fragment); Belongs to the serpin family.	Serpin-2 precursor, putative; Belongs to the serpin family.	0.537
B7P2Z9_IXOSC	B7PST4_IXOSC	B7P2Z9	B7PST4	Serpin, putative (Fragment); Belongs to the serpin family.	Serpin-4 precursor, putative; Belongs to the serpin family.	0.537
B7P2Z9_IXOSC	B7Q5W6_IXOSC	B7P2Z9	B7Q5W6	Serpin, putative (Fragment); Belongs to the serpin family.	Serpin-2 precursor, putative; Belongs to the serpin family.	0.537
B7P2Z9_IXOSC	B7QL30_IXOSC	B7P2Z9	B7QL30	Serpin, putative (Fragment); Belongs to the serpin family.	Serpin-2, putative; Belongs to the serpin family.	0.537
B7P2Z9_IXOSC	B7QL35_IXOSC	B7P2Z9	B7QL35	Serpin, putative (Fragment); Belongs to the serpin family.	Secreted salivary gland peptide, putative; Belongs to the serpin family.	0.537
B7P5V9_IXOSC	B7PVT7_IXOSC	B7P5V9	B7PVT7	Leucine-rich transmembrane protein, putative.	Uncharacterized protein.	0.448
B7P5V9_IXOSC	B7Q6L5_IXOSC	B7P5V9	B7Q6L5	Leucine-rich transmembrane protein, putative.	IG-like C2-type domain-containing protein, putative.	0.589
B7P5V9_IXOSC	B7QCV3_IXOSC	B7P5V9	B7QCV3	Leucine-rich transmembrane protein, putative.	No-mechanoreceptor potential A, putative.	0.562
B7P5V9_IXOSC	B7QDU0_IXOSC	B7P5V9	B7QDU0	Leucine-rich transmembrane protein, putative.	PAN domaincontaining protein.	0.448
B7P9C8_IXOSC	B7P9V6_IXOSC	B7P9C8	B7P9V6	Angiotensin-converting enzyme.	Peptidyldipeptidase A, putative.	0.496
B7P9J9_IXOSC	B7P9V6_IXOSC	B7P9J9	B7P9V6	Angiotensin-converting enzyme.	Peptidyldipeptidase A, putative.	0.490
B7P9V6_IXOSC	B7P1G7_IXOSC	B7P9V6	B7P1G7	Peptidyldipeptidase A, putative.	Angiotensin-converting enzyme.	0.490
B7P9V6_IXOSC	B7P9C8_IXOSC	B7P9V6	B7P9C8	Peptidyldipeptidase A, putative.	Angiotensin-converting enzyme.	0.496
B7P9V6_IXOSC	B7P9J9_IXOSC	B7P9V6	B7P9J9	Peptidyldipeptidase A, putative.	Angiotensin-converting enzyme.	0.490
B7P9V6_IXOSC	B7PNY9_IXOSC	B7P9V6	B7PNY9	Peptidyldipeptidase A, putative.	Angiotensin-converting enzyme.	0.494