(26 nodes) Mixed, incl. Phase 1 - inactivation of fast Na+ channels, and MASTL Facilitates Mitotic Progression network (Ixodes scapularis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B7P260_IXOSC	Serine/threonine protein kinase, putative. (178 aa)
	B7P2I5_IXOSC	Protein kinase, putative; Belongs to the protein kinase superfamily. (356 aa)
	B7P340_IXOSC	Splicing factor, arginine/serine-rich, putative. (457 aa)
	B7P4H5_IXOSC	Protein kinase, putative. (349 aa)
	B7P5W4_IXOSC	C2H2-type domain-containing protein. (546 aa)
	B7P671_IXOSC	Cement protein, putative. (324 aa)
	B7PFE4_IXOSC	FHA domaincontaining protein. (774 aa)
	B7PGW4_IXOSC	Vacuolar sorting protein 9 (vps9) domaincontaining protein. (263 aa)
	B7PKE2_IXOSC	Serine/threonine protein kinase, putative (Fragment). (747 aa)
	B7PKE3_IXOSC	Protein kinase, putative (Fragment). (494 aa)
	B7PP69_IXOSC	LysM domain-containing protein. (262 aa)
	B7PTC0_IXOSC	Serine/threonine protein kinase, putative. (443 aa)
	B7PTH9_IXOSC	Bcl2/adenovirus E1b 19-kD protein-interacting protein, putative. (193 aa)
	B7PWJ1_IXOSC	Grb2 associated binder (Gab), putative. (212 aa)
	B7Q0A0_IXOSC	Uncharacterized protein. (143 aa)
	B7Q1J2_IXOSC	Serine/threonine protein kinase, putative. (531 aa)
	B7Q1L9_IXOSC	Phorbol-ester/DAG-type domain-containing protein. (448 aa)
	B7Q1T0_IXOSC	Cyclin, putative. (334 aa)
	B7Q4W8_IXOSC	Regulator of ATP-sensitive K+ channel, putative. (87 aa)
	B7Q8C3_IXOSC	Uncharacterized protein. (286 aa)
	B7QDQ4_IXOSC	Ip63 protein, putative. (266 aa)
	B7QF53_IXOSC	PH domain-containing protein. (958 aa)
	B7QGS4_IXOSC	Microtubule associated serine/threonine kinase, putative (Fragment). (1321 aa)
	B7QIR3_IXOSC	Regulator of ATP-sensitive K+ channels, putative; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (122 aa)
	B7QJM8_IXOSC	Serine/threonine protein kinase, putative. (427 aa)
	B7QNP1_IXOSC	MAP kinase-activated protein kinase, putative. (364 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P260_IXOSC	B7Q4W8_IXOSC	B7P260	B7Q4W8	Serine/threonine protein kinase, putative.	Regulator of ATP-sensitive K+ channel, putative.	0.419
B7P260_IXOSC	B7QIR3_IXOSC	B7P260	B7QIR3	Serine/threonine protein kinase, putative.	Regulator of ATP-sensitive K+ channels, putative; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family.	0.419
B7P2I5_IXOSC	B7P671_IXOSC	B7P2I5	B7P671	Protein kinase, putative; Belongs to the protein kinase superfamily.	Cement protein, putative.	0.648
B7P2I5_IXOSC	B7Q1T0_IXOSC	B7P2I5	B7Q1T0	Protein kinase, putative; Belongs to the protein kinase superfamily.	Cyclin, putative.	0.668
B7P2I5_IXOSC	B7QDQ4_IXOSC	B7P2I5	B7QDQ4	Protein kinase, putative; Belongs to the protein kinase superfamily.	Ip63 protein, putative.	0.599
B7P340_IXOSC	B7P671_IXOSC	B7P340	B7P671	Splicing factor, arginine/serine-rich, putative.	Cement protein, putative.	0.451
B7P340_IXOSC	B7Q1T0_IXOSC	B7P340	B7Q1T0	Splicing factor, arginine/serine-rich, putative.	Cyclin, putative.	0.608
B7P4H5_IXOSC	B7Q4W8_IXOSC	B7P4H5	B7Q4W8	Protein kinase, putative.	Regulator of ATP-sensitive K+ channel, putative.	0.800
B7P4H5_IXOSC	B7QIR3_IXOSC	B7P4H5	B7QIR3	Protein kinase, putative.	Regulator of ATP-sensitive K+ channels, putative; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family.	0.800
B7P4H5_IXOSC	B7QNP1_IXOSC	B7P4H5	B7QNP1	Protein kinase, putative.	MAP kinase-activated protein kinase, putative.	0.873
B7P671_IXOSC	B7P2I5_IXOSC	B7P671	B7P2I5	Cement protein, putative.	Protein kinase, putative; Belongs to the protein kinase superfamily.	0.648
B7P671_IXOSC	B7P340_IXOSC	B7P671	B7P340	Cement protein, putative.	Splicing factor, arginine/serine-rich, putative.	0.451
B7PFE4_IXOSC	B7PWJ1_IXOSC	B7PFE4	B7PWJ1	FHA domaincontaining protein.	Grb2 associated binder (Gab), putative.	0.891
B7PGW4_IXOSC	B7Q1L9_IXOSC	B7PGW4	B7Q1L9	Vacuolar sorting protein 9 (vps9) domaincontaining protein.	Phorbol-ester/DAG-type domain-containing protein.	0.422
B7PKE2_IXOSC	B7Q4W8_IXOSC	B7PKE2	B7Q4W8	Serine/threonine protein kinase, putative (Fragment).	Regulator of ATP-sensitive K+ channel, putative.	0.419
B7PKE2_IXOSC	B7QIR3_IXOSC	B7PKE2	B7QIR3	Serine/threonine protein kinase, putative (Fragment).	Regulator of ATP-sensitive K+ channels, putative; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family.	0.419
B7PKE3_IXOSC	B7Q4W8_IXOSC	B7PKE3	B7Q4W8	Protein kinase, putative (Fragment).	Regulator of ATP-sensitive K+ channel, putative.	0.419
B7PKE3_IXOSC	B7QIR3_IXOSC	B7PKE3	B7QIR3	Protein kinase, putative (Fragment).	Regulator of ATP-sensitive K+ channels, putative; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family.	0.419
B7PP69_IXOSC	B7Q0A0_IXOSC	B7PP69	B7Q0A0	LysM domain-containing protein.	Uncharacterized protein.	0.611
B7PTC0_IXOSC	B7Q4W8_IXOSC	B7PTC0	B7Q4W8	Serine/threonine protein kinase, putative.	Regulator of ATP-sensitive K+ channel, putative.	0.419