(13 nodes) Fanconi Anemia Pathway network (Ixodes scapularis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B7P0Q7_IXOSC	Uncharacterized protein. (97 aa)
	B7P5X1_IXOSC	Fanconi anemia group D2 protein, putative (Fragment). (1195 aa)
	B7PJJ6_IXOSC	BTB domain-containing protein. (1015 aa)
	B7PSI8_IXOSC	ERCC4 domain-containing protein. (501 aa)
	B7PSJ3_IXOSC	Nuclear transport factor, putative. (101 aa)
	B7PW25_IXOSC	GIY-YIG domain-containing protein, putative (Fragment). (246 aa)
	B7PXV9_IXOSC	Centromere protein S, putative. (105 aa)
	B7Q500_IXOSC	Fanconi anemia, complementation group i, putative. (169 aa)
	B7Q501_IXOSC	Uncharacterized protein. (349 aa)
	B7Q630_IXOSC	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (542 aa)
	B7Q7G6_IXOSC	Uncharacterized protein. (112 aa)
	B7QH20_IXOSC	Uncharacterized protein. (100 aa)
	B7QKM0_IXOSC	E3 ubiquitin protein ligase FANCL, putative. (167 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P0Q7_IXOSC	B7P5X1_IXOSC	B7P0Q7	B7P5X1	Uncharacterized protein.	Fanconi anemia group D2 protein, putative (Fragment).	0.744
B7P0Q7_IXOSC	B7PJJ6_IXOSC	B7P0Q7	B7PJJ6	Uncharacterized protein.	BTB domain-containing protein.	0.757
B7P0Q7_IXOSC	B7PSI8_IXOSC	B7P0Q7	B7PSI8	Uncharacterized protein.	ERCC4 domain-containing protein.	0.530
B7P0Q7_IXOSC	B7PSJ3_IXOSC	B7P0Q7	B7PSJ3	Uncharacterized protein.	Nuclear transport factor, putative.	0.484
B7P0Q7_IXOSC	B7PW25_IXOSC	B7P0Q7	B7PW25	Uncharacterized protein.	GIY-YIG domain-containing protein, putative (Fragment).	0.812
B7P0Q7_IXOSC	B7Q500_IXOSC	B7P0Q7	B7Q500	Uncharacterized protein.	Fanconi anemia, complementation group i, putative.	0.627
B7P0Q7_IXOSC	B7Q501_IXOSC	B7P0Q7	B7Q501	Uncharacterized protein.	Uncharacterized protein.	0.627
B7P0Q7_IXOSC	B7Q630_IXOSC	B7P0Q7	B7Q630	Uncharacterized protein.	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	0.563
B7P0Q7_IXOSC	B7QH20_IXOSC	B7P0Q7	B7QH20	Uncharacterized protein.	Uncharacterized protein.	0.530
B7P0Q7_IXOSC	B7QKM0_IXOSC	B7P0Q7	B7QKM0	Uncharacterized protein.	E3 ubiquitin protein ligase FANCL, putative.	0.477
B7P5X1_IXOSC	B7P0Q7_IXOSC	B7P5X1	B7P0Q7	Fanconi anemia group D2 protein, putative (Fragment).	Uncharacterized protein.	0.744
B7P5X1_IXOSC	B7PJJ6_IXOSC	B7P5X1	B7PJJ6	Fanconi anemia group D2 protein, putative (Fragment).	BTB domain-containing protein.	0.707
B7P5X1_IXOSC	B7PSI8_IXOSC	B7P5X1	B7PSI8	Fanconi anemia group D2 protein, putative (Fragment).	ERCC4 domain-containing protein.	0.977
B7P5X1_IXOSC	B7PSJ3_IXOSC	B7P5X1	B7PSJ3	Fanconi anemia group D2 protein, putative (Fragment).	Nuclear transport factor, putative.	0.929
B7P5X1_IXOSC	B7PW25_IXOSC	B7P5X1	B7PW25	Fanconi anemia group D2 protein, putative (Fragment).	GIY-YIG domain-containing protein, putative (Fragment).	0.757
B7P5X1_IXOSC	B7PXV9_IXOSC	B7P5X1	B7PXV9	Fanconi anemia group D2 protein, putative (Fragment).	Centromere protein S, putative.	0.958
B7P5X1_IXOSC	B7Q500_IXOSC	B7P5X1	B7Q500	Fanconi anemia group D2 protein, putative (Fragment).	Fanconi anemia, complementation group i, putative.	0.973
B7P5X1_IXOSC	B7Q501_IXOSC	B7P5X1	B7Q501	Fanconi anemia group D2 protein, putative (Fragment).	Uncharacterized protein.	0.973
B7P5X1_IXOSC	B7Q630_IXOSC	B7P5X1	B7Q630	Fanconi anemia group D2 protein, putative (Fragment).	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	0.990
B7P5X1_IXOSC	B7Q7G6_IXOSC	B7P5X1	B7Q7G6	Fanconi anemia group D2 protein, putative (Fragment).	Uncharacterized protein.	0.959