(27 nodes) Mostly uncharacterized, incl. Frs2-mediated activation, and Positive regulation of pentose-phosphate shunt network (Ixodes scapularis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B7P0Z3_IXOSC	Uncharacterized protein. (544 aa)
	B7P8W2_IXOSC	Nerve growth factor receptor TRKA, putative. (368 aa)
	B7P9M2_IXOSC	Kinase suppressor of Ras (KSR), putative (Fragment). (916 aa)
	B7PAJ0_IXOSC	Serine/threonine protein kinase, putative (Fragment); Belongs to the protein kinase superfamily. (306 aa)
	B7PJL0_IXOSC	Regulator of G protein signaling, putative (Fragment). (1065 aa)
	B7PJL2_IXOSC	Regulator of g protein signaling, putative. (104 aa)
	B7PJL5_IXOSC	Uncharacterized protein. (1052 aa)
	B7PN38_IXOSC	Uncharacterized protein. (114 aa)
	B7PNJ8_IXOSC	Low-density lipoprotein receptor, putative. (1753 aa)
	B7PP73_IXOSC	Mitogen-activated protein kinase kinase MKK4, putative (Fragment); Belongs to the protein kinase superfamily. (385 aa)
	B7PPF1_IXOSC	GTP-binding protein Rhes, putative (Fragment). (209 aa)
	B7PS40_IXOSC	Sprouty, putative. (189 aa)
	B7PSP3_IXOSC	Non-specific protein-tyrosine kinase. (674 aa)
	B7PWD2_IXOSC	Ubiquitin family protein. (791 aa)
	B7Q5I4_IXOSC	Multifunctional chaperone, putative; Belongs to the 14-3-3 family. (258 aa)
	B7Q5K7_IXOSC	Uncharacterized protein. (413 aa)
	B7Q903_IXOSC	Pole hole family protein. (667 aa)
	B7QA36_IXOSC	RAS-related protein, putative. (184 aa)
	B7QFM0_IXOSC	Tyrosine kinase, putative. (442 aa)
	B7QGJ2_IXOSC	Uncharacterized protein. (2382 aa)
	B7QGQ3_IXOSC	143-3 isoform A isoform 2 family protein; Belongs to the 14-3-3 family. (101 aa)
	B7QGX7_IXOSC	KA1 domain-containing protein. (356 aa)
	B7QGX8_IXOSC	Serine/threonine protein kinase, putative (Fragment). (492 aa)
	B7QIQ5_IXOSC	Kinase suppressor of Ras (KSR), putative. (686 aa)
	B7QKV7_IXOSC	Non-specific serine/threonine protein kinase. (841 aa)
	B7QMZ1_IXOSC	LIM domain kinase 2, putative. (202 aa)
	B7QMZ2_IXOSC	Lim-kinase1, putative. (162 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P0Z3_IXOSC	B7P8W2_IXOSC	B7P0Z3	B7P8W2	Uncharacterized protein.	Nerve growth factor receptor TRKA, putative.	0.511
B7P0Z3_IXOSC	B7P9M2_IXOSC	B7P0Z3	B7P9M2	Uncharacterized protein.	Kinase suppressor of Ras (KSR), putative (Fragment).	0.503
B7P0Z3_IXOSC	B7PJL0_IXOSC	B7P0Z3	B7PJL0	Uncharacterized protein.	Regulator of G protein signaling, putative (Fragment).	0.629
B7P0Z3_IXOSC	B7PJL2_IXOSC	B7P0Z3	B7PJL2	Uncharacterized protein.	Regulator of g protein signaling, putative.	0.629
B7P0Z3_IXOSC	B7PN38_IXOSC	B7P0Z3	B7PN38	Uncharacterized protein.	Uncharacterized protein.	0.520
B7P0Z3_IXOSC	B7PSP3_IXOSC	B7P0Z3	B7PSP3	Uncharacterized protein.	Non-specific protein-tyrosine kinase.	0.517
B7P0Z3_IXOSC	B7PWD2_IXOSC	B7P0Z3	B7PWD2	Uncharacterized protein.	Ubiquitin family protein.	0.979
B7P0Z3_IXOSC	B7Q5K7_IXOSC	B7P0Z3	B7Q5K7	Uncharacterized protein.	Uncharacterized protein.	0.617
B7P0Z3_IXOSC	B7Q903_IXOSC	B7P0Z3	B7Q903	Uncharacterized protein.	Pole hole family protein.	0.503
B7P0Z3_IXOSC	B7QFM0_IXOSC	B7P0Z3	B7QFM0	Uncharacterized protein.	Tyrosine kinase, putative.	0.625
B7P0Z3_IXOSC	B7QGJ2_IXOSC	B7P0Z3	B7QGJ2	Uncharacterized protein.	Uncharacterized protein.	0.979
B7P0Z3_IXOSC	B7QIQ5_IXOSC	B7P0Z3	B7QIQ5	Uncharacterized protein.	Kinase suppressor of Ras (KSR), putative.	0.503
B7P0Z3_IXOSC	B7QMZ1_IXOSC	B7P0Z3	B7QMZ1	Uncharacterized protein.	LIM domain kinase 2, putative.	0.617
B7P0Z3_IXOSC	B7QMZ2_IXOSC	B7P0Z3	B7QMZ2	Uncharacterized protein.	Lim-kinase1, putative.	0.617
B7P8W2_IXOSC	B7P0Z3_IXOSC	B7P8W2	B7P0Z3	Nerve growth factor receptor TRKA, putative.	Uncharacterized protein.	0.511
B7P8W2_IXOSC	B7PAJ0_IXOSC	B7P8W2	B7PAJ0	Nerve growth factor receptor TRKA, putative.	Serine/threonine protein kinase, putative (Fragment); Belongs to the protein kinase superfamily.	0.514
B7P8W2_IXOSC	B7PJL0_IXOSC	B7P8W2	B7PJL0	Nerve growth factor receptor TRKA, putative.	Regulator of G protein signaling, putative (Fragment).	0.577
B7P8W2_IXOSC	B7PJL2_IXOSC	B7P8W2	B7PJL2	Nerve growth factor receptor TRKA, putative.	Regulator of g protein signaling, putative.	0.577
B7P8W2_IXOSC	B7PP73_IXOSC	B7P8W2	B7PP73	Nerve growth factor receptor TRKA, putative.	Mitogen-activated protein kinase kinase MKK4, putative (Fragment); Belongs to the protein kinase superfamily.	0.492
B7P8W2_IXOSC	B7Q5I4_IXOSC	B7P8W2	B7Q5I4	Nerve growth factor receptor TRKA, putative.	Multifunctional chaperone, putative; Belongs to the 14-3-3 family.	0.446