(10 nodes) Mixed, incl. Frs2-mediated activation, and Positive regulation of pentose-phosphate shunt network (Ixodes scapularis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	B7P9M2_IXOSC	Kinase suppressor of Ras (KSR), putative (Fragment). (916 aa)
	B7PP73_IXOSC	Mitogen-activated protein kinase kinase MKK4, putative (Fragment); Belongs to the protein kinase superfamily. (385 aa)
	B7PPF1_IXOSC	GTP-binding protein Rhes, putative (Fragment). (209 aa)
	B7Q5I4_IXOSC	Multifunctional chaperone, putative; Belongs to the 14-3-3 family. (258 aa)
	B7Q903_IXOSC	Pole hole family protein. (667 aa)
	B7QA36_IXOSC	RAS-related protein, putative. (184 aa)
	B7QGQ3_IXOSC	143-3 isoform A isoform 2 family protein; Belongs to the 14-3-3 family. (101 aa)
	B7QGX7_IXOSC	KA1 domain-containing protein. (356 aa)
	B7QGX8_IXOSC	Serine/threonine protein kinase, putative (Fragment). (492 aa)
	B7QKV7_IXOSC	Non-specific serine/threonine protein kinase. (841 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P9M2_IXOSC	B7PP73_IXOSC	B7P9M2	B7PP73	Kinase suppressor of Ras (KSR), putative (Fragment).	Mitogen-activated protein kinase kinase MKK4, putative (Fragment); Belongs to the protein kinase superfamily.	0.973
B7P9M2_IXOSC	B7PPF1_IXOSC	B7P9M2	B7PPF1	Kinase suppressor of Ras (KSR), putative (Fragment).	GTP-binding protein Rhes, putative (Fragment).	0.513
B7P9M2_IXOSC	B7Q5I4_IXOSC	B7P9M2	B7Q5I4	Kinase suppressor of Ras (KSR), putative (Fragment).	Multifunctional chaperone, putative; Belongs to the 14-3-3 family.	0.827
B7P9M2_IXOSC	B7Q903_IXOSC	B7P9M2	B7Q903	Kinase suppressor of Ras (KSR), putative (Fragment).	Pole hole family protein.	0.881
B7P9M2_IXOSC	B7QA36_IXOSC	B7P9M2	B7QA36	Kinase suppressor of Ras (KSR), putative (Fragment).	RAS-related protein, putative.	0.513
B7P9M2_IXOSC	B7QGQ3_IXOSC	B7P9M2	B7QGQ3	Kinase suppressor of Ras (KSR), putative (Fragment).	143-3 isoform A isoform 2 family protein; Belongs to the 14-3-3 family.	0.827
B7P9M2_IXOSC	B7QGX7_IXOSC	B7P9M2	B7QGX7	Kinase suppressor of Ras (KSR), putative (Fragment).	KA1 domain-containing protein.	0.543
B7P9M2_IXOSC	B7QGX8_IXOSC	B7P9M2	B7QGX8	Kinase suppressor of Ras (KSR), putative (Fragment).	Serine/threonine protein kinase, putative (Fragment).	0.617
B7P9M2_IXOSC	B7QKV7_IXOSC	B7P9M2	B7QKV7	Kinase suppressor of Ras (KSR), putative (Fragment).	Non-specific serine/threonine protein kinase.	0.774
B7PP73_IXOSC	B7P9M2_IXOSC	B7PP73	B7P9M2	Mitogen-activated protein kinase kinase MKK4, putative (Fragment); Belongs to the protein kinase superfamily.	Kinase suppressor of Ras (KSR), putative (Fragment).	0.973
B7PP73_IXOSC	B7PPF1_IXOSC	B7PP73	B7PPF1	Mitogen-activated protein kinase kinase MKK4, putative (Fragment); Belongs to the protein kinase superfamily.	GTP-binding protein Rhes, putative (Fragment).	0.581
B7PP73_IXOSC	B7Q5I4_IXOSC	B7PP73	B7Q5I4	Mitogen-activated protein kinase kinase MKK4, putative (Fragment); Belongs to the protein kinase superfamily.	Multifunctional chaperone, putative; Belongs to the 14-3-3 family.	0.841
B7PP73_IXOSC	B7Q903_IXOSC	B7PP73	B7Q903	Mitogen-activated protein kinase kinase MKK4, putative (Fragment); Belongs to the protein kinase superfamily.	Pole hole family protein.	0.997
B7PP73_IXOSC	B7QA36_IXOSC	B7PP73	B7QA36	Mitogen-activated protein kinase kinase MKK4, putative (Fragment); Belongs to the protein kinase superfamily.	RAS-related protein, putative.	0.581
B7PP73_IXOSC	B7QGQ3_IXOSC	B7PP73	B7QGQ3	Mitogen-activated protein kinase kinase MKK4, putative (Fragment); Belongs to the protein kinase superfamily.	143-3 isoform A isoform 2 family protein; Belongs to the 14-3-3 family.	0.841
B7PP73_IXOSC	B7QGX8_IXOSC	B7PP73	B7QGX8	Mitogen-activated protein kinase kinase MKK4, putative (Fragment); Belongs to the protein kinase superfamily.	Serine/threonine protein kinase, putative (Fragment).	0.499
B7PP73_IXOSC	B7QKV7_IXOSC	B7PP73	B7QKV7	Mitogen-activated protein kinase kinase MKK4, putative (Fragment); Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.685
B7PPF1_IXOSC	B7P9M2_IXOSC	B7PPF1	B7P9M2	GTP-binding protein Rhes, putative (Fragment).	Kinase suppressor of Ras (KSR), putative (Fragment).	0.513
B7PPF1_IXOSC	B7PP73_IXOSC	B7PPF1	B7PP73	GTP-binding protein Rhes, putative (Fragment).	Mitogen-activated protein kinase kinase MKK4, putative (Fragment); Belongs to the protein kinase superfamily.	0.581
B7PPF1_IXOSC	B7Q5I4_IXOSC	B7PPF1	B7Q5I4	GTP-binding protein Rhes, putative (Fragment).	Multifunctional chaperone, putative; Belongs to the 14-3-3 family.	0.447