(42 nodes) Mixed, incl. Tubulin, and Microtubule plus-end binding network (Ixodes scapularis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B7P453_IXOSC	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (386 aa)
	B7P462_IXOSC	Tubulin domain-containing protein. (90 aa)
	B7P4Z1_IXOSC	EF-Hand domain-containing protein, putative. (115 aa)
	B7P5B9_IXOSC	Kelch motif protein. (627 aa)
	B7P794_IXOSC	Microtubule-associated protein CP224, putative (Fragment). (1763 aa)
	B7P872_IXOSC	Alpha tubulin, putative; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (634 aa)
	B7P8K9_IXOSC	Beta tubulin, putative (Fragment); Belongs to the tubulin family. (465 aa)
	B7PA92_IXOSC	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
	B7PA95_IXOSC	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
	B7PAD5_IXOSC	Microtubule-binding protein, putative (Fragment). (275 aa)
	B7PAY8_IXOSC	Calbindin-32, putative. (63 aa)
	B7PCA7_IXOSC	Uncharacterized protein. (105 aa)
	B7PFY0_IXOSC	Chitin binding peritrophina domain-containing protein. (304 aa)
	B7PGI8_IXOSC	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (499 aa)
	B7PH43_IXOSC	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
	B7PHB5_IXOSC	Calponin/transgelin, putative. (135 aa)
	B7PHB6_IXOSC	Calponin, putative. (172 aa)
	B7PHK4_IXOSC	Beta-tubulin, putative; Belongs to the tubulin family. (300 aa)
	B7PNG4_IXOSC	Alpha tubulin, putative; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (271 aa)
	B7PPL3_IXOSC	Microtubule-binding protein, putative. (283 aa)
	B7PQ74_IXOSC	Uncharacterized protein. (67 aa)
	B7PXU8_IXOSC	CAP-Gly domain-containing linker protein, putative. (1036 aa)
	B7PZG2_IXOSC	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (239 aa)
	B7PZJ0_IXOSC	Mucin-7, putative (Fragment). (270 aa)
	B7Q0Q5_IXOSC	Alpha-tubulin, putative. (203 aa)
	B7Q0U9_IXOSC	Myosin light chain kinase, putative (Fragment). (597 aa)
	B7Q0X0_IXOSC	DUF667 domain-containing protein. (193 aa)
	B7Q3P3_IXOSC	Tubulin alpha-1 chain, putative. (39 aa)
	B7Q418_IXOSC	CAPGly domain-containing protein. (1108 aa)
	B7Q5L2_IXOSC	Transgelin; Belongs to the calponin family. (190 aa)
	B7Q5R5_IXOSC	Double-cortin, putative. (230 aa)
	B7Q5V8_IXOSC	Tubulin beta chain, putative. (65 aa)
	B7Q717_IXOSC	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (456 aa)
	B7QC47_IXOSC	Adipophilin/perilipin, putative. (420 aa)
	B7QC75_IXOSC	Proline rich secreted protein, putative (Fragment). (201 aa)
	B7QGK4_IXOSC	WD-repeat protein, putative (Fragment). (590 aa)
	B7QHZ2_IXOSC	Cuticular protein, putative. (321 aa)
	B7QLF1_IXOSC	Uncharacterized protein. (3701 aa)
	B7QN23_IXOSC	EF-Hand domain-containing protein, putative (Fragment). (171 aa)
	B7QND8_IXOSC	Tubulin alpha-1 chain, putative (Fragment). (64 aa)
	B7QP04_IXOSC	Alpha tubulin, putative; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (394 aa)
	B7QP06_IXOSC	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P453_IXOSC	B7P462_IXOSC	B7P453	B7P462	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin domain-containing protein.	0.659
B7P453_IXOSC	B7P794_IXOSC	B7P453	B7P794	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Microtubule-associated protein CP224, putative (Fragment).	0.577
B7P453_IXOSC	B7P8K9_IXOSC	B7P453	B7P8K9	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Beta tubulin, putative (Fragment); Belongs to the tubulin family.	0.635
B7P453_IXOSC	B7PA92_IXOSC	B7P453	B7PA92	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.872
B7P453_IXOSC	B7PA95_IXOSC	B7P453	B7PA95	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.872
B7P453_IXOSC	B7PAD5_IXOSC	B7P453	B7PAD5	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Microtubule-binding protein, putative (Fragment).	0.483
B7P453_IXOSC	B7PHB5_IXOSC	B7P453	B7PHB5	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Calponin/transgelin, putative.	0.477
B7P453_IXOSC	B7PHB6_IXOSC	B7P453	B7PHB6	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Calponin, putative.	0.470
B7P453_IXOSC	B7PHK4_IXOSC	B7P453	B7PHK4	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Beta-tubulin, putative; Belongs to the tubulin family.	0.874
B7P453_IXOSC	B7PNG4_IXOSC	B7P453	B7PNG4	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Alpha tubulin, putative; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	0.877
B7P453_IXOSC	B7PPL3_IXOSC	B7P453	B7PPL3	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Microtubule-binding protein, putative.	0.483
B7P453_IXOSC	B7PZG2_IXOSC	B7P453	B7PZG2	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	0.873
B7P453_IXOSC	B7Q0U9_IXOSC	B7P453	B7Q0U9	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Myosin light chain kinase, putative (Fragment).	0.752
B7P453_IXOSC	B7Q0X0_IXOSC	B7P453	B7Q0X0	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	DUF667 domain-containing protein.	0.493
B7P453_IXOSC	B7Q5L2_IXOSC	B7P453	B7Q5L2	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Transgelin; Belongs to the calponin family.	0.470
B7P453_IXOSC	B7Q5R5_IXOSC	B7P453	B7Q5R5	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Double-cortin, putative.	0.581
B7P453_IXOSC	B7Q5V8_IXOSC	B7P453	B7Q5V8	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin beta chain, putative.	0.756
B7P453_IXOSC	B7Q717_IXOSC	B7P453	B7Q717	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	0.873
B7P453_IXOSC	B7QGK4_IXOSC	B7P453	B7QGK4	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	WD-repeat protein, putative (Fragment).	0.581
B7P453_IXOSC	B7QND8_IXOSC	B7P453	B7QND8	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin alpha-1 chain, putative (Fragment).	0.522