(50 nodes) Telomere maintenance network (Ixodes scapularis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B7QAS3_IXOSC	Replication factor A 1, rfa1, putative. (217 aa)
	B7QKM2_IXOSC	Vasa protein isoform, putative (Fragment). (171 aa)
	B7QIF1_IXOSC	Cgi-121, putative; Belongs to the CGI121/TPRKB family. (151 aa)
	B7QI11_IXOSC	DNA ligase IV, putative (Fragment); Belongs to the ATP-dependent DNA ligase family. (817 aa)
	B7QGX0_IXOSC	Uncharacterized protein. (56 aa)
	B7QG93_IXOSC	Uncharacterized protein. (573 aa)
	B7QFM1_IXOSC	DNA cross-link repair protein pso2/snm1, putative. (248 aa)
	B7QFB5_IXOSC	Uncharacterized protein. (873 aa)
	B7QF19_IXOSC	Fkbp-rapamycin associated protein, putative; Belongs to the PI3/PI4-kinase family. (3070 aa)
	B7QF01_IXOSC	Nibrin, putative. (738 aa)
	B7QCE0_IXOSC	Uncharacterized protein. (883 aa)
	B7QCD9_IXOSC	Uncharacterized protein. (375 aa)
	B7QBG5_IXOSC	ATP-dependent DNA helicase. (372 aa)
	B7QBB8_IXOSC	Ribosomal protein kinase, putative. (639 aa)
	B7Q9Y6_IXOSC	Rif1_N domain-containing protein. (1766 aa)
	B7Q9B1_IXOSC	DNA repair protein RAD51/RHP55, putative. (319 aa)
	B7Q847_IXOSC	ATP-dependent DNA helicase; Belongs to the helicase family. (269 aa)
	B7Q7K0_IXOSC	Uncharacterized protein. (359 aa)
	B7Q5G3_IXOSC	DNA repair protein RAD51/RHP55, putative. (354 aa)
	B7Q4R6_IXOSC	Ku P70 DNA helicase, putative (Fragment). (575 aa)
	B7Q0Q8_IXOSC	Replication factor A 1, rfa1, putative. (347 aa)
	B7PZ77_IXOSC	NFRKB_winged domain-containing protein. (401 aa)
	B7PZ54_IXOSC	SMC protein, putative. (160 aa)
	B7PXQ5_IXOSC	Uncharacterized protein. (486 aa)
	B7PW21_IXOSC	DEAD_2 protein domain containing protein. (805 aa)
	B7PVL0_IXOSC	ATP-dependent DNA helicase; Belongs to the helicase family. (230 aa)
	B7PUX8_IXOSC	UME (NUC010) domaincontaining protein. (666 aa)
	B7PUX7_IXOSC	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1019 aa)
	B7PT39_IXOSC	Rep-A_N domain-containing protein. (158 aa)
	B7PRV6_IXOSC	Uncharacterized protein. (69 aa)
	B7PLQ6_IXOSC	Tetratricopeptide repeat protein, tpr, putative. (111 aa)
	B7PLQ5_IXOSC	ATP-dependent DNA helicase; Belongs to the helicase family. (263 aa)
	B7PIM4_IXOSC	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. (687 aa)
	B7PEX6_IXOSC	HELICc2 domain-containing protein. (280 aa)
	B7PC76_IXOSC	Uncharacterized protein. (107 aa)
	B7PC73_IXOSC	ATP-dependent DNA helicase (Fragment) (Fragment). (228 aa)
	B7PAR3_IXOSC	Peptidase C50 domain-containing protein. (365 aa)
	B7PA44_IXOSC	Uncharacterized protein. (488 aa)
	B7PA43_IXOSC	DNAdependent protein kinase catalytic subunit isoform 7 family protein. (500 aa)
	B7PA41_IXOSC	NUC194 domaincontaining protein. (1206 aa)
	B7P1I6_IXOSC	Oral cancer overexpressed protein, putative. (123 aa)
	B7P1K3_IXOSC	SMC protein, putative (Fragment). (1258 aa)
	B7P329_IXOSC	Ataxia telangiectasia mutated, putative (Fragment); Belongs to the PI3/PI4-kinase family. (380 aa)
	B7P330_IXOSC	Ataxia telangiectasia mutated, putative (Fragment). (338 aa)
	B7P331_IXOSC	Uncharacterized protein. (440 aa)
	B7P366_IXOSC	Mitotic and DNA damage checkpoint protein hus1, putative. (283 aa)
	B7P576_IXOSC	Tetratricopeptide repeat protein, tpr, putative. (186 aa)
	B7PA40_IXOSC	Protein kinase, DNAactivated, catalytic polypeptide; Belongs to the PI3/PI4-kinase family. (256 aa)
	B7PA39_IXOSC	mDNApk3', putative; Belongs to the PI3/PI4-kinase family. (239 aa)
	B7QLU7_IXOSC	Uncharacterized protein. (60 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P1K3_IXOSC	B7P329_IXOSC	B7P1K3	B7P329	SMC protein, putative (Fragment).	Ataxia telangiectasia mutated, putative (Fragment); Belongs to the PI3/PI4-kinase family.	0.761
B7P1K3_IXOSC	B7P330_IXOSC	B7P1K3	B7P330	SMC protein, putative (Fragment).	Ataxia telangiectasia mutated, putative (Fragment).	0.761
B7P1K3_IXOSC	B7P331_IXOSC	B7P1K3	B7P331	SMC protein, putative (Fragment).	Uncharacterized protein.	0.761
B7P1K3_IXOSC	B7P366_IXOSC	B7P1K3	B7P366	SMC protein, putative (Fragment).	Mitotic and DNA damage checkpoint protein hus1, putative.	0.572
B7P1K3_IXOSC	B7PC73_IXOSC	B7P1K3	B7PC73	SMC protein, putative (Fragment).	ATP-dependent DNA helicase (Fragment) (Fragment).	0.486
B7P1K3_IXOSC	B7PC76_IXOSC	B7P1K3	B7PC76	SMC protein, putative (Fragment).	Uncharacterized protein.	0.716
B7P1K3_IXOSC	B7PEX6_IXOSC	B7P1K3	B7PEX6	SMC protein, putative (Fragment).	HELICc2 domain-containing protein.	0.464
B7P1K3_IXOSC	B7PIM4_IXOSC	B7P1K3	B7PIM4	SMC protein, putative (Fragment).	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase.	0.716
B7P1K3_IXOSC	B7PT39_IXOSC	B7P1K3	B7PT39	SMC protein, putative (Fragment).	Rep-A_N domain-containing protein.	0.644
B7P1K3_IXOSC	B7PUX7_IXOSC	B7P1K3	B7PUX7	SMC protein, putative (Fragment).	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.895
B7P1K3_IXOSC	B7PUX8_IXOSC	B7P1K3	B7PUX8	SMC protein, putative (Fragment).	UME (NUC010) domaincontaining protein.	0.845
B7P1K3_IXOSC	B7PVL0_IXOSC	B7P1K3	B7PVL0	SMC protein, putative (Fragment).	ATP-dependent DNA helicase; Belongs to the helicase family.	0.468
B7P1K3_IXOSC	B7PW21_IXOSC	B7P1K3	B7PW21	SMC protein, putative (Fragment).	DEAD_2 protein domain containing protein.	0.464
B7P1K3_IXOSC	B7PZ54_IXOSC	B7P1K3	B7PZ54	SMC protein, putative (Fragment).	SMC protein, putative.	0.497
B7P1K3_IXOSC	B7Q0Q8_IXOSC	B7P1K3	B7Q0Q8	SMC protein, putative (Fragment).	Replication factor A 1, rfa1, putative.	0.664
B7P1K3_IXOSC	B7Q4R6_IXOSC	B7P1K3	B7Q4R6	SMC protein, putative (Fragment).	Ku P70 DNA helicase, putative (Fragment).	0.955
B7P1K3_IXOSC	B7Q5G3_IXOSC	B7P1K3	B7Q5G3	SMC protein, putative (Fragment).	DNA repair protein RAD51/RHP55, putative.	0.828
B7P1K3_IXOSC	B7Q9B1_IXOSC	B7P1K3	B7Q9B1	SMC protein, putative (Fragment).	DNA repair protein RAD51/RHP55, putative.	0.822
B7P1K3_IXOSC	B7QAS3_IXOSC	B7P1K3	B7QAS3	SMC protein, putative (Fragment).	Replication factor A 1, rfa1, putative.	0.664
B7P1K3_IXOSC	B7QCD9_IXOSC	B7P1K3	B7QCD9	SMC protein, putative (Fragment).	Uncharacterized protein.	0.761