(44 nodes) Regulation of tube size network (Ixodes scapularis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B7QNG7_IXOSC	Ig-like domain-containing protein. (85 aa)
	B7QHI4_IXOSC	Alpha-actinin, putative. (130 aa)
	B7QGG7_IXOSC	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (2750 aa)
	B7QF57_IXOSC	Autophagy protein 5; Involved in autophagic vesicle formation. (194 aa)
	B7QB03_IXOSC	Chaperone protein DNAj, putative (Fragment). (370 aa)
	B7QA57_IXOSC	Chitin-binding type-2 domain-containing protein. (529 aa)
	B7QA28_IXOSC	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (138 aa)
	B7Q593_IXOSC	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (452 aa)
	B7Q543_IXOSC	Chitin-binding type-2 domain-containing protein. (120 aa)
	B7Q520_IXOSC	Protein 4.1G, putative. (864 aa)
	B7Q4T8_IXOSC	SP-RING-type domain-containing protein. (851 aa)
	B7Q3W2_IXOSC	Uncharacterized protein. (229 aa)
	B7Q343_IXOSC	Esterase, putative. (583 aa)
	B7Q314_IXOSC	Uncharacterized protein. (143 aa)
	B7Q301_IXOSC	Uncharacterized protein. (1615 aa)
	B7Q1Z8_IXOSC	Neuronal cell adhesion molecule, putative. (1224 aa)
	B7PZH8_IXOSC	UDP-N-acetylglucosamine pyrophosphorylase, putative (Fragment). (477 aa)
	B7PX27_IXOSC	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (296 aa)
	B7PVH6_IXOSC	CABIT domain-containing protein. (621 aa)
	B7PUK8_IXOSC	Clathrin heavy chain, putative (Fragment). (1616 aa)
	B7PU54_IXOSC	DNA-binding protein elf-1, putative (Fragment). (536 aa)
	B7PT49_IXOSC	Neural cell adhesion molecule, putative. (333 aa)
	B7PKK5_IXOSC	GTPase Rho, putative. (82 aa)
	B7PII2_IXOSC	Uncharacterized protein. (477 aa)
	B7PII1_IXOSC	Chitin synthase, putative. (1562 aa)
	B7PIH8_IXOSC	Chitin synthase, putative. (811 aa)
	B7PHU6_IXOSC	Dishevelled protein, putative (Fragment). (610 aa)
	B7PH66_IXOSC	GTPase Rho, putative. (192 aa)
	B7PH65_IXOSC	GTPase Rho, putative (Fragment). (205 aa)
	B7PH64_IXOSC	Cdc42 protein, putative. (201 aa)
	B7PGH0_IXOSC	Protein quiver. (139 aa)
	B7PFE2_IXOSC	Four-jointed box protein, putative. (385 aa)
	B7PAT6_IXOSC	Uncharacterized protein. (137 aa)
	B7P9Y8_IXOSC	Protocadherin-16, putative. (3222 aa)
	B7P9Y6_IXOSC	Protocadherin fat, putative. (1590 aa)
	B7P8X6_IXOSC	Cdc42 protein, putative (Fragment). (238 aa)
	B7P5V9_IXOSC	Leucine-rich transmembrane protein, putative. (818 aa)
	B7P5M3_IXOSC	Hemolin, putative. (270 aa)
	B7P4B9_IXOSC	Secreted mucin MUC17, putative. (3497 aa)
	B7P3A9_IXOSC	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (111 aa)
	B7P2E9_IXOSC	Protocadherin-16, putative. (2493 aa)
	B7P1W0_IXOSC	Uncharacterized protein. (462 aa)
	B7P1J6_IXOSC	GTPase Rho, putative. (228 aa)
	B7QNM3_IXOSC	Uncharacterized protein. (241 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P1J6_IXOSC	B7PHU6_IXOSC	B7P1J6	B7PHU6	GTPase Rho, putative.	Dishevelled protein, putative (Fragment).	0.460
B7P1J6_IXOSC	B7PUK8_IXOSC	B7P1J6	B7PUK8	GTPase Rho, putative.	Clathrin heavy chain, putative (Fragment).	0.489
B7P2E9_IXOSC	B7P9Y6_IXOSC	B7P2E9	B7P9Y6	Protocadherin-16, putative.	Protocadherin fat, putative.	0.718
B7P2E9_IXOSC	B7P9Y8_IXOSC	B7P2E9	B7P9Y8	Protocadherin-16, putative.	Protocadherin-16, putative.	0.718
B7P2E9_IXOSC	B7PFE2_IXOSC	B7P2E9	B7PFE2	Protocadherin-16, putative.	Four-jointed box protein, putative.	0.663
B7P3A9_IXOSC	B7PUK8_IXOSC	B7P3A9	B7PUK8	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	Clathrin heavy chain, putative (Fragment).	0.545
B7P3A9_IXOSC	B7PX27_IXOSC	B7P3A9	B7PX27	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.630
B7P5M3_IXOSC	B7PT49_IXOSC	B7P5M3	B7PT49	Hemolin, putative.	Neural cell adhesion molecule, putative.	0.497
B7P5M3_IXOSC	B7QNG7_IXOSC	B7P5M3	B7QNG7	Hemolin, putative.	Ig-like domain-containing protein.	0.497
B7P5M3_IXOSC	B7QNM3_IXOSC	B7P5M3	B7QNM3	Hemolin, putative.	Uncharacterized protein.	0.456
B7P8X6_IXOSC	B7PHU6_IXOSC	B7P8X6	B7PHU6	Cdc42 protein, putative (Fragment).	Dishevelled protein, putative (Fragment).	0.460
B7P8X6_IXOSC	B7PUK8_IXOSC	B7P8X6	B7PUK8	Cdc42 protein, putative (Fragment).	Clathrin heavy chain, putative (Fragment).	0.489
B7P9Y6_IXOSC	B7P2E9_IXOSC	B7P9Y6	B7P2E9	Protocadherin fat, putative.	Protocadherin-16, putative.	0.718
B7P9Y6_IXOSC	B7PFE2_IXOSC	B7P9Y6	B7PFE2	Protocadherin fat, putative.	Four-jointed box protein, putative.	0.510
B7P9Y8_IXOSC	B7P2E9_IXOSC	B7P9Y8	B7P2E9	Protocadherin-16, putative.	Protocadherin-16, putative.	0.718
B7P9Y8_IXOSC	B7PFE2_IXOSC	B7P9Y8	B7PFE2	Protocadherin-16, putative.	Four-jointed box protein, putative.	0.510
B7PAT6_IXOSC	B7QNM3_IXOSC	B7PAT6	B7QNM3	Uncharacterized protein.	Uncharacterized protein.	0.471
B7PFE2_IXOSC	B7P2E9_IXOSC	B7PFE2	B7P2E9	Four-jointed box protein, putative.	Protocadherin-16, putative.	0.663
B7PFE2_IXOSC	B7P9Y6_IXOSC	B7PFE2	B7P9Y6	Four-jointed box protein, putative.	Protocadherin fat, putative.	0.510
B7PFE2_IXOSC	B7P9Y8_IXOSC	B7PFE2	B7P9Y8	Four-jointed box protein, putative.	Protocadherin-16, putative.	0.510