(44 nodes) Hair cell differentiation network (Ixodes scapularis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B7P1J6_IXOSC	GTPase Rho, putative. (228 aa)
	B7P2E9_IXOSC	Protocadherin-16, putative. (2493 aa)
	B7P6L6_IXOSC	PDZ domain-containing protein, putative (Fragment). (875 aa)
	B7P8V7_IXOSC	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (323 aa)
	B7P8X6_IXOSC	Cdc42 protein, putative (Fragment). (238 aa)
	B7P8Z3_IXOSC	ANK_REP_REGION domain-containing protein. (82 aa)
	B7P8Z4_IXOSC	ANK_REP_REGION domain-containing protein. (103 aa)
	B7P8Z7_IXOSC	Forked family protein. (173 aa)
	B7P9Y6_IXOSC	Protocadherin fat, putative. (1590 aa)
	B7P9Y8_IXOSC	Protocadherin-16, putative. (3222 aa)
	B7PE75_IXOSC	Fascin. (460 aa)
	B7PEG8_IXOSC	Transcriptional factor nfil3/e4bp4, putative. (380 aa)
	B7PFE2_IXOSC	Four-jointed box protein, putative. (385 aa)
	B7PH64_IXOSC	Cdc42 protein, putative. (201 aa)
	B7PH65_IXOSC	GTPase Rho, putative (Fragment). (205 aa)
	B7PH66_IXOSC	GTPase Rho, putative. (192 aa)
	B7PHU6_IXOSC	Dishevelled protein, putative (Fragment). (610 aa)
	B7PIM9_IXOSC	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (463 aa)
	B7PKK5_IXOSC	GTPase Rho, putative. (82 aa)
	B7PKL2_IXOSC	C4b-binding protein beta chain, putative. (793 aa)
	B7PLY5_IXOSC	Uncharacterized protein. (459 aa)
	B7PN05_IXOSC	SMC protein, putative (Fragment). (188 aa)
	B7PN71_IXOSC	Vang-like protein. (569 aa)
	B7PPU2_IXOSC	Shavenoid family protein. (264 aa)
	B7PV81_IXOSC	Leucine rich domain-containing protein, putative (Fragment). (1327 aa)
	B7PXB6_IXOSC	GBD/FH3 domain-containing protein. (751 aa)
	B7Q199_IXOSC	RAS protein, putative (Fragment). (192 aa)
	B7Q2A3_IXOSC	SMC protein, putative. (846 aa)
	B7Q2J4_IXOSC	Uncharacterized protein. (195 aa)
	B7Q343_IXOSC	Esterase, putative. (583 aa)
	B7Q3Y1_IXOSC	RNA recognition motif protein, putative. (3850 aa)
	B7Q4S9_IXOSC	Rho-associated kinase, putative (Fragment); Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1245 aa)
	B7Q520_IXOSC	Protein 4.1G, putative. (864 aa)
	B7Q8X0_IXOSC	Guanine nucleotide exchange factor (GBF1), putative. (202 aa)
	B7QCS5_IXOSC	Furrowed, putative. (1056 aa)
	B7QEI4_IXOSC	Uncharacterized protein. (581 aa)
	B7QFJ3_IXOSC	Ankyrin repeats containing protein, putative (Fragment). (309 aa)
	B7QG96_IXOSC	Uncharacterized protein. (444 aa)
	B7QGG7_IXOSC	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (2750 aa)
	B7QGJ1_IXOSC	C2H2-type domain-containing protein. (502 aa)
	B7QKV7_IXOSC	Non-specific serine/threonine protein kinase. (841 aa)
	B7QLB5_IXOSC	Zinc finger protein, putative. (418 aa)
	B7QMZ1_IXOSC	LIM domain kinase 2, putative. (202 aa)
	B7QMZ2_IXOSC	Lim-kinase1, putative. (162 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P1J6_IXOSC	B7PHU6_IXOSC	B7P1J6	B7PHU6	GTPase Rho, putative.	Dishevelled protein, putative (Fragment).	0.460
B7P1J6_IXOSC	B7PIM9_IXOSC	B7P1J6	B7PIM9	GTPase Rho, putative.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.436
B7P1J6_IXOSC	B7PN71_IXOSC	B7P1J6	B7PN71	GTPase Rho, putative.	Vang-like protein.	0.435
B7P1J6_IXOSC	B7PXB6_IXOSC	B7P1J6	B7PXB6	GTPase Rho, putative.	GBD/FH3 domain-containing protein.	0.528
B7P1J6_IXOSC	B7Q4S9_IXOSC	B7P1J6	B7Q4S9	GTPase Rho, putative.	Rho-associated kinase, putative (Fragment); Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.617
B7P1J6_IXOSC	B7QFJ3_IXOSC	B7P1J6	B7QFJ3	GTPase Rho, putative.	Ankyrin repeats containing protein, putative (Fragment).	0.440
B7P2E9_IXOSC	B7P9Y6_IXOSC	B7P2E9	B7P9Y6	Protocadherin-16, putative.	Protocadherin fat, putative.	0.718
B7P2E9_IXOSC	B7P9Y8_IXOSC	B7P2E9	B7P9Y8	Protocadherin-16, putative.	Protocadherin-16, putative.	0.718
B7P2E9_IXOSC	B7PFE2_IXOSC	B7P2E9	B7PFE2	Protocadherin-16, putative.	Four-jointed box protein, putative.	0.663
B7P6L6_IXOSC	B7PHU6_IXOSC	B7P6L6	B7PHU6	PDZ domain-containing protein, putative (Fragment).	Dishevelled protein, putative (Fragment).	0.514
B7P6L6_IXOSC	B7PN71_IXOSC	B7P6L6	B7PN71	PDZ domain-containing protein, putative (Fragment).	Vang-like protein.	0.423
B7P6L6_IXOSC	B7QG96_IXOSC	B7P6L6	B7QG96	PDZ domain-containing protein, putative (Fragment).	Uncharacterized protein.	0.787
B7P6L6_IXOSC	B7QGG7_IXOSC	B7P6L6	B7QGG7	PDZ domain-containing protein, putative (Fragment).	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	0.559
B7P8V7_IXOSC	B7Q199_IXOSC	B7P8V7	B7Q199	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.	RAS protein, putative (Fragment).	0.402
B7P8V7_IXOSC	B7Q2J4_IXOSC	B7P8V7	B7Q2J4	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.	Uncharacterized protein.	0.402
B7P8X6_IXOSC	B7PHU6_IXOSC	B7P8X6	B7PHU6	Cdc42 protein, putative (Fragment).	Dishevelled protein, putative (Fragment).	0.460
B7P8X6_IXOSC	B7PIM9_IXOSC	B7P8X6	B7PIM9	Cdc42 protein, putative (Fragment).	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.436
B7P8X6_IXOSC	B7PN71_IXOSC	B7P8X6	B7PN71	Cdc42 protein, putative (Fragment).	Vang-like protein.	0.435
B7P8X6_IXOSC	B7PXB6_IXOSC	B7P8X6	B7PXB6	Cdc42 protein, putative (Fragment).	GBD/FH3 domain-containing protein.	0.528
B7P8X6_IXOSC	B7Q4S9_IXOSC	B7P8X6	B7Q4S9	Cdc42 protein, putative (Fragment).	Rho-associated kinase, putative (Fragment); Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.960