(48 nodes) Meiotic chromosome segregation network (Ixodes scapularis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B7P0Q7_IXOSC	Uncharacterized protein. (97 aa)
	B7P0Y2_IXOSC	Condensin-2 complex subunit H2, putative. (704 aa)
	B7P201_IXOSC	Ran GTPase-activating protein, putative. (527 aa)
	B7P2J6_IXOSC	Mitotic checkpoint serine/threonine protein kinase bub1 and bubr1, putative. (457 aa)
	B7P2J7_IXOSC	Spindle checkpoint protein bubr1, putative. (444 aa)
	B7P499_IXOSC	Kifc1, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (338 aa)
	B7P548_IXOSC	ERCC4 domain-containing protein. (361 aa)
	B7P5X1_IXOSC	Fanconi anemia group D2 protein, putative (Fragment). (1195 aa)
	B7P6J4_IXOSC	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (538 aa)
	B7P865_IXOSC	DNA repair endonuclease xp-f / mei-9 / rad1, putative. (775 aa)
	B7P8D9_IXOSC	Uncharacterized protein. (174 aa)
	B7PAH6_IXOSC	DNA mismatch repair protein mlh3, putative. (232 aa)
	B7PAH7_IXOSC	DNA mismatch repair protein mlh3, putative (Fragment). (354 aa)
	B7PAR3_IXOSC	Peptidase C50 domain-containing protein. (365 aa)
	B7PDK6_IXOSC	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (321 aa)
	B7PDK7_IXOSC	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (306 aa)
	B7PGQ1_IXOSC	DNA polymerase theta, putative (Fragment). (750 aa)
	B7PJJ7_IXOSC	Nipped-B protein. (2025 aa)
	B7PJP3_IXOSC	Transcription regulatory protein, putative. (512 aa)
	B7PQD0_IXOSC	MutS domain V domaincontaining protein. (253 aa)
	B7PQG9_IXOSC	Meiotic recombination protein Dmc1, putative; Belongs to the RecA family. (341 aa)
	B7PSI7_IXOSC	Uncharacterized protein. (1081 aa)
	B7PSI8_IXOSC	ERCC4 domain-containing protein. (501 aa)
	B7PT38_IXOSC	FERM domain-containing protein. (125 aa)
	B7PUC1_IXOSC	Condensin, putative. (1545 aa)
	B7PUX7_IXOSC	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1019 aa)
	B7PVZ6_IXOSC	Serine/threonine protein kinase PLK3, putative. (302 aa)
	B7PW27_IXOSC	Tbp-1 interacting protein, putative. (211 aa)
	B7PWZ4_IXOSC	Uncharacterized protein. (186 aa)
	B7PXU6_IXOSC	Uncharacterized protein. (819 aa)
	B7PZV4_IXOSC	Merlin, putative. (170 aa)
	B7Q3G5_IXOSC	Centromere/kinetochore protein zw10, putative. (707 aa)
	B7Q5U2_IXOSC	Ankle1 protein, putative. (670 aa)
	B7Q7G6_IXOSC	Uncharacterized protein. (112 aa)
	B7Q7M7_IXOSC	DNA replication licensing factor MCM5, putative; Belongs to the MCM family. (323 aa)
	B7Q951_IXOSC	Kinesin heavy chain isoform 5C, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (173 aa)
	B7Q9D3_IXOSC	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (96 aa)
	B7QBY2_IXOSC	RING-type domain-containing protein. (398 aa)
	B7QC65_IXOSC	Excision repair cross-complementing 1 ercc1, putative. (111 aa)
	B7QCH6_IXOSC	Uncharacterized protein. (874 aa)
	B7QCK5_IXOSC	Uncharacterized protein. (223 aa)
	B7QDF1_IXOSC	MutS domain V domaincontaining protein. (573 aa)
	B7QDF2_IXOSC	MutS_II domain-containing protein. (123 aa)
	B7QE45_IXOSC	Survivin, putative. (166 aa)
	B7QGY9_IXOSC	Kinesin, putative (Fragment); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (379 aa)
	B7QH20_IXOSC	Uncharacterized protein. (100 aa)
	B7QII9_IXOSC	Ubiquitin protein ligase, putative; Belongs to the ubiquitin-conjugating enzyme family. (174 aa)
	B7QKB6_IXOSC	Nuclear distribution gene E family 1 (A. nidulans), putative. (257 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P0Q7_IXOSC	B7P548_IXOSC	B7P0Q7	B7P548	Uncharacterized protein.	ERCC4 domain-containing protein.	0.994
B7P0Q7_IXOSC	B7P5X1_IXOSC	B7P0Q7	B7P5X1	Uncharacterized protein.	Fanconi anemia group D2 protein, putative (Fragment).	0.744
B7P0Q7_IXOSC	B7P865_IXOSC	B7P0Q7	B7P865	Uncharacterized protein.	DNA repair endonuclease xp-f / mei-9 / rad1, putative.	0.773
B7P0Q7_IXOSC	B7PGQ1_IXOSC	B7P0Q7	B7PGQ1	Uncharacterized protein.	DNA polymerase theta, putative (Fragment).	0.427
B7P0Q7_IXOSC	B7PSI7_IXOSC	B7P0Q7	B7PSI7	Uncharacterized protein.	Uncharacterized protein.	0.530
B7P0Q7_IXOSC	B7PSI8_IXOSC	B7P0Q7	B7PSI8	Uncharacterized protein.	ERCC4 domain-containing protein.	0.530
B7P0Q7_IXOSC	B7QC65_IXOSC	B7P0Q7	B7QC65	Uncharacterized protein.	Excision repair cross-complementing 1 ercc1, putative.	0.761
B7P0Q7_IXOSC	B7QH20_IXOSC	B7P0Q7	B7QH20	Uncharacterized protein.	Uncharacterized protein.	0.530
B7P0Y2_IXOSC	B7PUC1_IXOSC	B7P0Y2	B7PUC1	Condensin-2 complex subunit H2, putative.	Condensin, putative.	0.992
B7P201_IXOSC	B7PAR3_IXOSC	B7P201	B7PAR3	Ran GTPase-activating protein, putative.	Peptidase C50 domain-containing protein.	0.577
B7P201_IXOSC	B7QE45_IXOSC	B7P201	B7QE45	Ran GTPase-activating protein, putative.	Survivin, putative.	0.446
B7P201_IXOSC	B7QII9_IXOSC	B7P201	B7QII9	Ran GTPase-activating protein, putative.	Ubiquitin protein ligase, putative; Belongs to the ubiquitin-conjugating enzyme family.	0.998
B7P2J6_IXOSC	B7P499_IXOSC	B7P2J6	B7P499	Mitotic checkpoint serine/threonine protein kinase bub1 and bubr1, putative.	Kifc1, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.523
B7P2J6_IXOSC	B7P6J4_IXOSC	B7P2J6	B7P6J4	Mitotic checkpoint serine/threonine protein kinase bub1 and bubr1, putative.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.456
B7P2J6_IXOSC	B7PAR3_IXOSC	B7P2J6	B7PAR3	Mitotic checkpoint serine/threonine protein kinase bub1 and bubr1, putative.	Peptidase C50 domain-containing protein.	0.849
B7P2J6_IXOSC	B7PDK6_IXOSC	B7P2J6	B7PDK6	Mitotic checkpoint serine/threonine protein kinase bub1 and bubr1, putative.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.448
B7P2J6_IXOSC	B7PDK7_IXOSC	B7P2J6	B7PDK7	Mitotic checkpoint serine/threonine protein kinase bub1 and bubr1, putative.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.448
B7P2J6_IXOSC	B7PQG9_IXOSC	B7P2J6	B7PQG9	Mitotic checkpoint serine/threonine protein kinase bub1 and bubr1, putative.	Meiotic recombination protein Dmc1, putative; Belongs to the RecA family.	0.565
B7P2J6_IXOSC	B7PVZ6_IXOSC	B7P2J6	B7PVZ6	Mitotic checkpoint serine/threonine protein kinase bub1 and bubr1, putative.	Serine/threonine protein kinase PLK3, putative.	0.882
B7P2J6_IXOSC	B7Q3G5_IXOSC	B7P2J6	B7Q3G5	Mitotic checkpoint serine/threonine protein kinase bub1 and bubr1, putative.	Centromere/kinetochore protein zw10, putative.	0.683